Pioneering the Path to Pain Management: Discovering Unexplored Analgesic Targets in Anesthesia Research

A special issue of Anesthesia Research (ISSN 2813-5806).

Deadline for manuscript submissions: closed (31 July 2024) | Viewed by 1800

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Danube Neuroscience Research Laboratory, HUN-REN-SZTE Neuroscience Research Group, Hungarian Research Network, University of Szeged (HUN-REN-SZTE), Tisza Lajos krt. 113, H-6725 Szeged, Hungary
Interests: depression; anxiety; dementia pain; their comorbidities nature; translational research in neurological diseases and psychiatric disorders
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Special Issue Information

Dear Colleagues,

We are pleased to announce a Special Issue on 'Pioneering the Path to Pain Management: Discovering Unexplored Analgesic Targets in Anesthesia Research,' which aims to explore new avenues for pain relief in anesthesia practice. Pain management is a critical aspect of anesthesia practice, and there is a need for new analgesic targets that can improve patient outcomes and quality of life. This Special Issue aims to showcase cutting-edge research in this area and highlight the potential of unexplored analgesic targets. We invite original research papers, review articles, and case reports that focus on discovering new analgesic targets in anesthesia practice. Topics of interest include, but are not limited to, the mechanisms of action of new analgesics, their efficacy and safety, and their potential applications in different patient populations. This Special Issue will provide a platform for researchers to share their latest findings and contribute to the advancement of pain management in anesthesia practice. The published papers will have the potential to inform clinical practice, improve patient care, and inspire further research in this important area. This Special Issue highlights the most recent advances in experimental, clinical, and translational research in the fields of anesthesia research, focusing on novel targets for pain management. We welcome submissions from researchers and practitioners in the field of anesthesia research and look forward to receiving your papers focusing on (but not limited to) the following:

  • Etiology, pathogenesis, and progression mechanisms;
  • Early diagnosis including biomarkers, bio-imaging, and biosensors;
  • Prophylactic, disease-modifying and therapeutic strategies, novel targets;
  • Novel drug discovery and development, naturally driven biomedicines, natural bioactive molecules, and vaccines;
  • Preclinical in vitro models and animal models;
  • Bench-to-bedside translational research;
  • Bedside-to-bench translational research.

Thank you for your interest in this important Special Issue.

Dr. Masaru Tanaka
Guest Editor

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Keywords

  • acute postoperative pain
  • multimodal analgesia
  • opioid-sparing techniques
  • procedure-specific pain management
  • pain generators
  • non-pharmacologic therapy
  • regional anesthetic techniques
  • non-opioid pharmacotherapy
  • novel opioids
  • personalized pain management

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Published Papers (1 paper)

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13 pages, 2158 KiB  
Article
Ultrasound-Guided Interphalangeal Injection (US-IPI) of Mucoid Cysts as a Non-Surgical Option: Technical Notes and Clinical Efficacy
by Eliodoro Faiella, Elva Vergantino, Domiziana Santucci, Amalia Bruno, Giuseppina Pacella, Vincenzo Panasiti, Bruno Beomonte Zobel and Rosario Francesco Grasso
Anesth. Res. 2024, 1(2), 67-79; https://doi.org/10.3390/anesthres1020008 - 1 Aug 2024
Viewed by 937
Abstract
Digital mucous cysts (DMCs) are common soft tissue tumors affecting interphalangeal joints. Various treatment options exist, with surgical excision being the standard. Ultrasound-guided cortisone (CC) injection into the distal interphalangeal (DIP) joint has been proposed as a therapeutic alternative. This study aims to [...] Read more.
Digital mucous cysts (DMCs) are common soft tissue tumors affecting interphalangeal joints. Various treatment options exist, with surgical excision being the standard. Ultrasound-guided cortisone (CC) injection into the distal interphalangeal (DIP) joint has been proposed as a therapeutic alternative. This study aims to assess the technical success and clinical efficacy of US-IPI in terms of swelling resolution and pain control. Fifty-two patients with DMCs underwent CCs DIP joint ultrasound-guided infiltration. Eighty-three percent of patients exhibited a positive response to US-IPI, with a significant reduction in NRS pain scores (p < 0.01). Persistent pain in 17% of patients was effectively managed with marked improvement after a secondary infiltration. Joint swelling was reduced in 68% of patients within 1 month, with complete resolution by 3 to 6 months. No recurrence was reported at the 6-month follow-up. Pain assessment using the Numeric Rating Scale and joint swelling evaluation were conducted at follow-ups of 2 weeks, 1, 3, and 6 months. Statistical analysis was performed to compare pre- and post-procedure NRS pain scores. Here, we show that US-IPI of DMCs is an effective therapeutic option that provides immediate pain relief and long-term aesthetic improvement, resulting in an alternative option to surgical excision. Full article
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