Companion Animal Nutrition and Gut Health

A special issue of Animals (ISSN 2076-2615). This special issue belongs to the section "Companion Animals".

Deadline for manuscript submissions: closed (31 August 2025) | Viewed by 984

Special Issue Editor


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Guest Editor
Animal Production Department, Faculty of Veterinary Medicine, Universidad Complutense de Madrid, Avda. Puerta de Hierro s/n., 28040 Madrid, Spain
Interests: nutrition; gut health; antioxidants; lipids; bioactive compounds; monogastric animals; pets
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Special Issue Information

Dear Colleagues,

Pet food manufacturing is an increasingly booming sector that tends to incorporate new bioactive compounds to ensure health, prevent diseases and try to alleviate symptoms in cases of diseases of unknown etiology. The relationship between diet and the composition of the microbiome has recently been demonstrated, and therefore its influence on homeostasis and intestinal health has been highlighted. This is a key aspect since a healthy intestine favors the functionality of its microorganisms that in turn produce metabolites with important regulatory functions on metabolism and at a systemic level, and in turn can act as biomarkers of intestinal health. In addition, the study of different food components, new ingredients or supplements with probiotic, prebiotic or postbiotic action and their effects on the intestinal health of our pets is still a very unresearched aspect that requires further study.

As a guest editor, I invite you to submit your latest research findings or a review article to this Special Issue, which will bring together current research on nutrition and intestinal health of companion animals. These investigations may include the use of different compounds of natural or synthetic origin: from plant extracts, herbs, fruits or seeds, by-products of plant-based ingredients, proteins; fats; vitamins, minerals, etc., applied to the diet of pets, in which their administration produces positive or negative effects on intestinal health. Research evaluating the presence of bioactive compounds in the body as biomarkers of intestinal health is also welcome.

Dr. Ana Isabel Rey Muñoz
Guest Editor

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Animals is an international peer-reviewed open access semimonthly journal published by MDPI.

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Keywords

  • pet nutrition
  • gut health
  • chronic gut diseases
  • microbiome
  • microbiota–gut–brain axis

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Published Papers (1 paper)

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Review

27 pages, 1231 KB  
Review
Markers of Gut Health in Small Animals: Focus on Fatty Acids and Amino Acids as Indicators of Intestinal Functionality and Microbiome Activity
by Ana I. Rey, Cristina Higueras, Patricia Olmeda, Angel Sainz, Beatriz G. Gálvez and Mar Larrosa
Animals 2025, 15(13), 1927; https://doi.org/10.3390/ani15131927 - 30 Jun 2025
Viewed by 670
Abstract
Chronic inflammatory enteropathies (CIEs) in companion animals represent a group of idiopathic, immune-mediated gastrointestinal disorders in which the intestinal epithelium can be altered, affecting intestinal functionality, nutrient absorption, and microbiota composition. This review presents an overview of markers that could be used for [...] Read more.
Chronic inflammatory enteropathies (CIEs) in companion animals represent a group of idiopathic, immune-mediated gastrointestinal disorders in which the intestinal epithelium can be altered, affecting intestinal functionality, nutrient absorption, and microbiota composition. This review presents an overview of markers that could be used for the assessment of intestinal health, focusing extensively on functional biomarkers, with particular attention to fatty acids (including short-chain fatty acids, SCFAs) and amino acids. Studies have consistently shown reduced concentrations of SCFAs in companion animals with CIEs compared to healthy groups. These alterations occur with varying intensity depending on the type of enteropathy. Alterations in saturated, monounsaturated, and long-chain polyunsaturated fatty acids have also been reported in blood and feces, particularly in omega-3 and omega-6 derivatives, as well as in the elongase and desaturase indices responsible for endogenous synthesis. In addition, amino acids serve as precursors to key metabolites involved in mucosal immunity, oxidative stress regulation, and microbial homeostasis. In CIEs, alterations in systemic and fecal amino acid profiles have been observed, reflecting both host metabolic adaptation and microbial dysbiosis. Integrating fatty acid and amino acid profiles can help distinguish different types of enteropathies, providing additional discriminatory power for determining response to dietary treatment. Future research should aim to elucidate the causal relationships between metabolic alterations and disease pathogenesis, which could lead to novel dietary interventions targeting metabolic interactions between the microbiota and the host. Full article
(This article belongs to the Special Issue Companion Animal Nutrition and Gut Health)
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