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Animals
Special Issues
New Perspectives in Porcine Epidemic Diarrhea Virus (PEDV)
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New Perspectives in Porcine Epidemic Diarrhea Virus (PEDV)

A special issue of Animals (ISSN 2076-2615). This special issue belongs to the section "Veterinary Clinical Studies".

Deadline for manuscript submissions: closed (30 November 2023) | Viewed by 3887

Special Issue Editors

Dr. Jianbo Liu

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Guest Editor
State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute of Chinese Academy of Agricultural Sciences, Harbin 150001, China
Interests: porcine epidemic diarrhea virus; animal coronaviruses
Special Issues, Collections and Topics in MDPI journals
Dr. Jianing Chen

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Guest Editor
State Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou 730046, China
Interests: cross-species transmission; pathogenicity of swine coronaviruses
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Porcine epidemic diarrhea virus (PEDV) is a coronavirus of swine, a member of the Coronaviridae subfamily and the family Nidovirales. PEDV mainly attacks the gastrointestinal tract and causes the destruction of villous enterocytes and villous atrophy, resulting in high morbidity and mortality in both newborn and suckling pigs, leading to serious economic losses in the swine industry. Thus, it is very important to research the virus.

The aim of this Special Issue is to collect the newest contributions in the field of PEDV research, providing new insights and addressing research on unresolved issues. Research areas may include (but are not limited to) the following: evolution, viral replication, virus–host interaction, pathogenesis and immunity, gene therapy, viral oncotherapy, and novel antiviral strategies. All researchers working in the field are cordially invited to contribute original research papers or propose reviews to this Special Issue of Animals.

We look forward to receiving your contributions.

Dr. Jianbo Liu
Dr. Jianing Chen
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Animals is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • porcine epidemic diarrhea virus
  • viral replication
  • virus–host interaction
  • pathogenesis and immunity
  • novel antiviral strategies
  • molecular epidemiology

Related Special Issue

Published Papers (2 papers)

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Review

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14 pages, 1323 KiB  
Review
Porcine Epidemic Diarrhea Virus: Etiology, Epidemiology, Antigenicity, and Control Strategies in China
by Jianlin Lei, Yongqiang Miao, Wenrui Bi, Chaohui Xiang, Wei Li, Riteng Zhang, Qian Li and Zengqi Yang
Animals 2024, 14(2), 294; https://doi.org/10.3390/ani14020294 - 17 Jan 2024
Cited by 1 | Viewed by 1867
Abstract
Porcine epidemic diarrhea virus (PEDV) is a porcine enteric coronavirus, which is one of the main causative agents of porcine epidemic diarrhea (PED), with 100% morbidity and 80–100% mortality in neonatal piglets. Since 2010, large-scale PED caused by highly pathogenic variants of PEDV [...] Read more.
Porcine epidemic diarrhea virus (PEDV) is a porcine enteric coronavirus, which is one of the main causative agents of porcine epidemic diarrhea (PED), with 100% morbidity and 80–100% mortality in neonatal piglets. Since 2010, large-scale PED caused by highly pathogenic variants of PEDV has occurred successively in China and other countries in the world, posing a great threat to the global pig industry. It has been demonstrated in many investigations that the classic attenuated vaccine strain, PEDV CV777, is insufficient to fully protect against the PEDV variants. Moreover, the maternally derived antibodies elicited by inactivated vaccines also cannot completely protect piglets from infection. In addition, feedback feeding poses a risk of periodic PEDV recurrence in pig farms, making it challenging to successfully limit the spread of PEDV in China. This review focuses on the etiology, epidemiology, antigenicity, and control strategies of PEDV in China and provides information for the formulation of effective control measures. Full article
(This article belongs to the Special Issue New Perspectives in Porcine Epidemic Diarrhea Virus (PEDV))
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Other

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9 pages, 3273 KiB  
Brief Report
Molecular Characterization and Phylogenetic Analysis of a Variant Recombinant Porcine Epidemic Diarrhea Virus Strain in China
by Xiaoliang Hu, Yuexiao Lian, Yucan He, Xiangxiao Liu, Zhige Tian, Yi Dai, Mengyuan Liu, Huayan Fan, Yue Shi and Feng Cong
Animals 2022, 12(17), 2189; https://doi.org/10.3390/ani12172189 - 25 Aug 2022
Cited by 5 | Viewed by 1594
Abstract
Since 2010, a variant of porcine epidemic diarrhea virus (PEDV) has re-emerged in several provinces of China, resulting in severe economic losses for the pork industry. Here, we isolated and identified a variant PEDV strain, SC-YB73, in Guangdong Province, China. The pathological observations [...] Read more.
Since 2010, a variant of porcine epidemic diarrhea virus (PEDV) has re-emerged in several provinces of China, resulting in severe economic losses for the pork industry. Here, we isolated and identified a variant PEDV strain, SC-YB73, in Guangdong Province, China. The pathological observations of jejunum showed atrophy of villi and edema in the lamina propria. The sequence analysis of the viral genome identified a six-nucleotide insertion in the E gene, which has not previously been detected in PEDV strains. Furthermore, 50 nucleotide sites were unique in SC-YB73 compared with 27 other PEDV strains. The phylogenetic analysis based on the complete genome showed that SC-YB73 was clustered in variant subgroup GII-a, which is widely prevalent in the Chinese pig population. The recombination analysis suggested that SC-YB73 originated from the recombination of GDS47, US PEDV prototype-like strains TW/Yunlin550/2018, and COL/Cundinamarca/2014. In the present study, we isolated and genetically characterized a variant PEDV strain, thus providing essential information for the control of PED outbreaks in China. Full article
(This article belongs to the Special Issue New Perspectives in Porcine Epidemic Diarrhea Virus (PEDV))
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