Animal Nutritional Genomics

A special issue of Animals (ISSN 2076-2615). This special issue belongs to the section "Animal Nutrition".

Deadline for manuscript submissions: closed (19 August 2021) | Viewed by 4351

Special Issue Editor


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Guest Editor
School of Health, Medical and Applied Sciences, Central Queensland University, North Rockhampton, Australia
Interests: intestinal health; probiotics; microbial ecology; livestock research; immunology
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Nutritional genomics, also known as nutrigenomics, is the study of the effects of food on the gene expression of the host. In animals, especially livestock placed long-term on a specific nutritional formula, the lack of nutritional diversity amplifies the effects the individual feed ingredients may have on the host. Recent research has been highlighting the role of regularly consumed micro- and macro-nutrients in disease predisposition and organ toxicology. In this Special Issue, we invite manuscripts that explore the use of feed and feed ingredients in manipulating the gene expression profile of the host toward better health, immunity, and stress responses, as well as manuscripts that reveal the adverse transcriptional effects that some common foods may have on the host.

Dr. Dana Stanley
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Animals is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Animal nutrition
  • nutrigenomics
  • transcriptomics
  • gene expression

Published Papers (1 paper)

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Research

15 pages, 3031 KiB  
Article
The Effects of Continual Consumption of Origanum vulgare on Liver Transcriptomics
by Yadav S. Bajagai, Anita Radovanovic, Jason C. Steel and Dragana Stanley
Animals 2021, 11(2), 398; https://doi.org/10.3390/ani11020398 - 4 Feb 2021
Cited by 5 | Viewed by 3716
Abstract
Pathogen control is re-emerging as a significant challenge to the health of both humans and animals. The livestock industry is in the process of massively replacing in-feed antibiotics with organic production friendly plant-based products. Nutrigenomics as a science of the effects of food [...] Read more.
Pathogen control is re-emerging as a significant challenge to the health of both humans and animals. The livestock industry is in the process of massively replacing in-feed antibiotics with organic production friendly plant-based products. Nutrigenomics as a science of the effects of food constituents on gene expression is shedding more light on both benefits and detrimental side-effects of feed additive prolonged consumption on the host, indicating the need to understand the feed-host interactions and their influence on the host disease profile. In this study, we investigated the effects of 2% oregano powder supplementation on the liver gene expression in healthy male broilers from the hatch to 6 weeks of age. Deep RNAseq was performed on average 113.3 million paired and quality trimmed sequences per sample and four samples for the control and treatment each. The results demonstrate the severity of oregano effect on liver gene expression with substantial modifications in steroid hormone regulation, fat and carbohydrate metabolism alterations and strong influence on the host disease and function profile. Oregano supplementation was able to interfere with the transcriptional effects of a range of registered drugs and to significantly transcriptionally inhibit a range of cancer disease categories including liver cancer, and to modify fat and carbohydrate metabolism. Full article
(This article belongs to the Special Issue Animal Nutritional Genomics)
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