Fetal Programming in Animal Species

A special issue of Animals (ISSN 2076-2615).

Deadline for manuscript submissions: closed (30 September 2022) | Viewed by 2411

Special Issue Editors


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Guest Editor
Department of Animal Science, University of Rhode Island, Kingston, RI, USA
Interests: fetal programming; calf health; DNA methylation; pancreas; physiology; RNA-seq

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Guest Editor
Department of Animal and Range Sciences, Montana State University, Bozeman, MT, USA
Interests: embryogenesis and placentation

Special Issue Information

Dear Colleagues,

The scope of this special issue would cover research that evaluates maternal/fetal programming events in animals. Fetal programming is defined as events that occur during pregnancy that can have long lasting effects on the growth and development of the offspring. Several different factors during pregnancy can have a programming effect including, but not limited to, the exposure of the mother to stress, disease, environmental toxins and alternations to nutrient availability. The articles that would be included in this issue would ideally cover a wide range of animal species (both livestock and non-livestock species) and different forms of maternal programming. The scope of articles that could be included in this issue would cover 1) how fetal programming alters the growth, metabolism and development of the offspring  2) novel mechanisms that are involved in mediating the effects of fetal programming during pregnancy in the mother and the offspring 3) determining the long-term effects of maternal programming across multiple generations (example: alterations to productivity, health and/or fecundity in subsequent generations) and 4) Understanding how the exposure to disease, stress, or other factor alters the placental development and the health of the mother during pregnancy. 

Dr. Maria Hoffman
Dr. Sarah McCoski
Guest Editors

Manuscript Submission Information

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Keywords

  • maternal programming
  • fetal programming
  • sheep
  • cattle
  • swine
  • growth
  • development
  • physiology
  • reproduction

Published Papers (1 paper)

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Research

17 pages, 506 KiB  
Article
Overnutrition of Ewe in Late Gestation and the Impact on Placental Efficiency and Lamb’s Performance
by Marco Antonio Paula de Sousa, Sergio Novita Esteves, Luciara Celi Chaves Daher, Sarita Bonagurio Gallo, Verônica Schinaider do Amaral Pereira, Jeferson Ferreira da Fonseca, André Guimarães Maciel e Silva, Felipe Zandonadi Brandão, Maria Emilia Franco Oliveira, Andréa do Nascimento Barreto, Gabriel Brun Vergani and Alexandre Rossetto Garcia
Animals 2023, 13(1), 103; https://doi.org/10.3390/ani13010103 - 27 Dec 2022
Cited by 2 | Viewed by 1744
Abstract
The objective of the study was to evaluate energy or energy/protein supplementation in the ewe diet, in the last third of gestation, on maternal placental and endocrine characteristics, as well as its effects on the behavior of neonatal lambs and productive performance until [...] Read more.
The objective of the study was to evaluate energy or energy/protein supplementation in the ewe diet, in the last third of gestation, on maternal placental and endocrine characteristics, as well as its effects on the behavior of neonatal lambs and productive performance until weaning. A total of 128 ewes were used, and the experimental diet was fed from 100 days gestation until lambing, with the birth of 172 lambs. The ewes were distributed into three treatments: CTL (control, n = 43) with metabolizable energy (ME) and crude protein (CP) intake according to NRC (1985); ME (energy supplementation, n = 44) plus 21% ME; and MECP (energy/protein supplementation, n = 41) plus 26% ME and CP. Body weight, body condition score, serum hormone concentrations, placental characteristics, lamb performance and behavior, and production efficiency of the ewe from lambing to weaning were measured. ME and MECP ewes were heavier before (p = 0.006) and just after lambing (p = 0.002) and had higher serum triiodothyronine (p = 0.001) and cortisol (p = 0.004) concentrations on the day of lambing. ME ewes had higher placental efficiency (p = 0.036) and lower total cotyledon weight (p = 0.011). ME and MECP diets increased both lamb birth weight (p = 0.015) and weaning weight (p = 0.009). Production efficiency at birth and at weaning was not influenced (p > 0.05) by treatments. Lamb behavior was influenced by the ME and MECP diets, reducing the time to kneel (p ≤ 0.05), to try to stand (p ≤ 0.05), and the latency to stand (p ≤ 0.005). It is concluded that overnutrition in the last third of gestation was positive for the ovine production system, with improved production rates, hormonal profile, placental characteristics, and neonatal behavior. Full article
(This article belongs to the Special Issue Fetal Programming in Animal Species)
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