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Animals
Special Issues
Glycobiology in Animals
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Glycobiology in Animals

A special issue of Animals (ISSN 2076-2615).

Deadline for manuscript submissions: closed (31 July 2021) | Viewed by 3579

Special Issue Editors

Prof. Dr. Salvatore Desantis

E-Mail Website
Guest Editor
Department of Emergency and Organ Transplantation (DETO), University of Bari Aldo Moro, S.P. 62 per Casamassima Km 3, 70010 Bari, Italy
Interests: glycan histochemistry; microarrays; histology; reproductive apparatus; digestive apparatus; stem cells
Prof. Dr. Maria Mastrodonato

E-Mail Website
Guest Editor
Departrment of Biology, University of Bari Aldo Moro, Bari, Italy
Interests: gastrointestinal mucins; lectin-histochemistry; hepatogastric system; electron microscopy; immunohistochemistry; immunocytochemistry
Prof. Dr. Giovanni Scillitani

E-Mail Website
Guest Editor
Departrment of Biology, University of Bari Aldo Moro, Bari, Italy
Interests: comparative glycobiology; amphibians; reptiles; digestive system; embryology; nanoparticles

Special Issue Information

Dear Colleagues,

Glycans have long been recognized as important structural components and functions in energy storage, but more recently, they have also been considered for their key role in constitution of cell glycocalyx, secreted products, biological fluids (plasma, urine, semen, saliva, breast milk), and for their implication in a variety of functions such as cell-to-cell interaction, locomotion, signaling, differentiation, and many others, including malignant transformation.

Despite the large amount of papers concerning glycobiology in the animal kingdom, there are numerous morphological, physiological, and molecular aspects that still require investigation.

Thus, original manuscripts and review articles dealing with glycans and glycoconjugates are invited for this Special Issue on “Glycobiology in Animals”.

Prof. Dr. Salvatore Desantis
Prof. Dr. Maria Mastrodonato
Prof. Dr. Scilitani Giovanni
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Animals is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Glycomics
  • Reproduction
  • Digestive apparatus
  • Stem cells
  • Poultry
  • Fish

Published Papers (1 paper)

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Research

21 pages, 5425 KiB  
Article
Modulation of Morphology and Glycan Composition of Mucins in Farmed Guinea Fowl (Numida meleagris) Intestine by the Multi-Strain Probiotic Slab51®
by Salvatore Desantis, Livio Galosi, Nicoletta Santamaria, Alessandra Roncarati, Lucia Biagini and Giacomo Rossi
Animals 2021, 11(2), 495; https://doi.org/10.3390/ani11020495 - 13 Feb 2021
Cited by 1 | Viewed by 2900
Abstract
Probiotics have become highly recognized as supplements for poultry.Since gut health can be considered synonymous withanimal health, the effects of probiotic Slab51® on the morphology and the glycan composition of guineafowlintestine were examined. The probiotics were added in drinking water (2 × [...] Read more.
Probiotics have become highly recognized as supplements for poultry.Since gut health can be considered synonymous withanimal health, the effects of probiotic Slab51® on the morphology and the glycan composition of guineafowlintestine were examined. The probiotics were added in drinking water (2 × 1011 UFC/L) throughout the grow-out cycle.Birds were individually weighed andslaughtered after four months. Samples from the duodenum, ileum and caecum were collected and processed for morphological, morphometric, conventional and lectin glycohistochemical studies.The results were analyzed for statistical significance by Student’s t test. Compared with control samples, probiotic group revealed (1) significant increase in villus height (p < 0.001 in duodenum and ileum; p < 0.05 in caecum), crypt depth (p < 0.001 in duodenum and caecum; p < 0.05 in ileum) and goblet cells (GCs) per villus (p < 0.001) in all investigated tracts; (2) increase in galactoseβl,3N-acetylgalacyosamine(Galβl,3GalNAc)terminating O-glycans and αl,2-fucosylated glycans secretory GCs in the duodenum; (3) increase in α2,6-sialoglycans and high-mannose N-linked glycans secretory GCs but reduction in GCs-secreting sulfoglycans in the ileum; (4) increase in Galβl,3GalNAc and high-mannose N-linked glycans secretory GCs and decrease in GCs-producing sulfomucins in the caecum; (5) increase in the numbers of crypt cells containing sulfate and non-sulfated acidic glycans. Overall, dietary Slab51® induces morphological and region-specific changes in glycoprotein composition of guinea fowl intestine, promoting gut health. Full article
(This article belongs to the Special Issue Glycobiology in Animals)
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