Cytokine Growth Factor Antibodies in Immunotherapy
A special issue of Antibodies (ISSN 2073-4468).
Deadline for manuscript submissions: closed (30 April 2013) | Viewed by 26047
Special Issue Editor
Special Issue Information
Dear Colleagues,
In this issue, we aim to draw together some of the latest research on antibodies directed against cytokines used in both research and clinical settings. Cytokines are small cell-signaling protein molecules secreted by cells of the immune system that regulate host responses to infection, inflammation, and trauma. Cytokines deliver signals between cells, and often across short distances during cell-to-cell interactions, which influence cellular growth and differentiation.
Antibodies directed against cytokines have had an enormous impact on biomedical research. Research Laboratories, pharmaceutical and biotechnology industries continue to focus on the development of antibodies directed against cytokines for the treatment of cancer, chronic inflammation and autoimmune diseases. Attention has focused on blocking cytokines, which are harmful to the host and using antibodies bound to cytokines to expand subsets of T cells that can regulate immune responses. Strategies include neutralizing antibodies, cytokine-cytokine antibody complexes, soluble receptors, receptor antagonist and targeting molecules that are important for the processing of cytokines.
Dr. Cecile King
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibodies is an international peer-reviewed open access quarterly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- cytokines
- growth factors
- anti-cytokine antibodies
- immune complexes
- autoimmunity
- cancer
- inflammation
- cytokine receptor trap
- potentiating antibodies
- neutralizing antibodies
- bioavailability