New Insights on the Blood–Brain Barrier and Brain Injury: Updates and New Directions
A special issue of Bioengineering (ISSN 2306-5354). This special issue belongs to the section "Regenerative Engineering".
Deadline for manuscript submissions: closed (31 May 2024) | Viewed by 2006
Special Issue Editors
Interests: blood–brain barrier; traumatic brain injury; tissue engineering; microfluidics
Interests: host-pathogen interaction between bacterial pathogens and the human blood-brain barrier
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The aim of this Special Issue is to provide an up-to-date review of the blood–brain barrier (BBB) and its role in brain injury. The BBB is a complex structure that regulates the exchange of substances between the blood and the brain, and it plays a critical role in maintaining the homeostasis of the central nervous system. Brain injury can disrupt the BBB, leading to the infiltration of blood-borne cells and substances into the brain, and contributing to the development of neurological disorders.
This Special Issue will cover new insights into the mechanisms of BBB dysfunction in brain injury, including traumatic brain injury, stroke, neurodegenerative diseases and infections of the CNS. It will also highlight the latest developments in BBB imaging and therapeutic strategies that target the BBB to prevent or treat brain injury.
The scope of this Special Issue includes, but is not limited to:
- Mechanisms of BBB dysfunction in brain injury;
- BBB imaging techniques;
- Therapeutic strategies for BBB protection and repair;
- Neuroinflammation and BBB disruption in neurodegenerative diseases;
- Regulation of BBB permeability and transporters;
- Biomarkers of BBB integrity and injury;
- Effects of bacterial and viral infection on the BBB.
The articles included in this Special Issue will provide a comprehensive and multidisciplinary approach to understanding the BBB and its role in brain injury, and will provide directions for future research in this important field.
Dr. Allison Andrews
Dr. Brandon Kim
Guest Editors
Manuscript Submission Information
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Keywords
- brain injury
- blood–brain barrier
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