Bioengineering Approaches in Lung Injury and Repair
A special issue of Bioengineering (ISSN 2306-5354). This special issue belongs to the section "Regenerative Engineering".
Deadline for manuscript submissions: 28 February 2026 | Viewed by 121
Special Issue Editor
Interests: noninvasive mechanical ventilation therapy; continuous positive airway pressure; acute lung injury; hypoxemic respiratory failure; ventilator-induced lung injury in non-invasive ventilatory support: pathophysiology, treatment and prevention
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Lung injury remains a critical challenge in clinical medicine, with various etiologies—including infections, toxic exposures, and chronic inflammatory diseases—leading to significant morbidity and mortality. This has driven a growing interest in bioengineering approaches aimed at understanding the mechanisms of lung injury and developing innovative strategies for repair and regeneration. The intersection of bioengineering, stem cell therapy, biomaterials, and mechanical ventilation techniques presents opportunities to revolutionize the management of lung injuries, enhancing patient outcomes and reducing long-term complications.
Non-invasive ventilatory support has emerged as a pivotal innovation in supporting patients with compromised lung function—particularly those suffering from neuromuscular disorders or severe respiratory diseases. This technology is particularly crucial during the management of lung injuries, as effective airway clearance can mitigate the progression of lung disease and promote a more favorable healing environment.
Recent advancements in stem cell therapy have opened new avenues for lung repair, with the potential to regenerate damaged tissues and restore normal lung function. These therapies leverage the unique properties of stem cells, such as their ability to differentiate into lung parenchymal cells and modulate inflammatory responses. Moreover, bioengineered scaffolds and biomaterial applications facilitate the delivery of these cells to the injury site, promoting tissue integration and repair. The development of such scaffolds is intricately linked with the understanding of lung biomechanics and the microenvironment to create conducive conditions for healing.
The bioengineering community continues to explore novel approaches, integrating the principles of engineering with biomedical research to develop advanced therapeutic modalities. As we delve into the complexities of lung injury and repair, it is essential to foster interdisciplinary collaborations that harness expertise across various fields. This Special Issue aims to compile cutting-edge research, clinical insights, and transformative bioengineering solutions for lung injury and repair, encouraging contributions that address both fundamental science and practical applications.
Dr. Antonio M. Esquinas
Guest Editor
Manuscript Submission Information
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Keywords
- bioengineering
- lung injury
- repair mechanisms
- stem cell therapy
- biomaterials
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