Medical Devices and Implants, 2nd Edition

A special issue of Bioengineering (ISSN 2306-5354). This special issue belongs to the section "Biomedical Engineering and Biomaterials".

Deadline for manuscript submissions: 30 October 2024 | Viewed by 945

Special Issue Editors


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Guest Editor
Department of Mechanical Engineering, University of Louisiana at Lafayette, Lafayette, LA, USA
Interests: computational and experimental biomechanics; machine learning; orthopaedic biomechanics; 3D Printing

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Guest Editor
Department of Mechanical Engineering, Embry-Riddle Aeronautical University, Daytona Beach, FL, USA
Interests: computational and experimental biomechanics; biomedical systems engineering; machine learning; robotics; space physiology

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Guest Editor
Department of Surgery, LSU Health Shreveport, Shreveport, LA 71103, USA
Interests: surgical devices; robotics; 3D printing; tissue engineering

Special Issue Information

Dear Colleagues,

We invite contributions to a Special Issue of Bioengineering focused on the design, prototyping, manufacturing, and experimentation of medical devices and implants. Considering the increased demand for these devices and thus increased healthcare costs, the clinical deployment of these solutions results in many challenges that need to be overcome. The regulatory compliance, absence of standardized testing procedures, manufacturability, and efficacy of these devices are examples of issues that need to be addressed to launch or maintain a product on the market with satisfactory clinical results. Embedded artificial intelligence in diagnostic tools, big-data-driven design processes, wireless communications for real-time monitoring, and finite element modeling for verification and validation are all examples of novel but now well-established technologies that have positively impacted product development. Further, the widespread use of additive manufacturing has boosted patient-specific design and implant development. More recently, bioprinting has been used in medicine to help to study or recreate almost every tissue, cartilage, and organ in the body. The translational role of these solutions is often overlooked, and they are not well covered in clinical journals. Therefore, this Special Issue aims to collect studies performed on medical devices and implants, strictly related to their development, prototyping, efficacy, and safety. Discussions and critical analyses of existing testing methods and standards are welcome, as are original studies on new concepts. We look forward to receiving your groundbreaking contributions.

Dr. Tanvir Faisal
Dr. Christine Walck
Dr. Donald Sorrells
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Bioengineering is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • implant
  • medical devices
  • prototyping
  • 3D printing
  • scaffolds
  • tissue engineering
  • additive manufacturing

Published Papers (2 papers)

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Research

11 pages, 3120 KiB  
Article
Smart Drill for a Streamlined Estimation of the Drilling Angle and Channel Length in Orthopedic Surgical Procedures
by Arsen Ivanišević, Zvonimir Boban, Josip Jurić and Katarina Vukojević
Bioengineering 2024, 11(6), 630; https://doi.org/10.3390/bioengineering11060630 - 19 Jun 2024
Viewed by 231
Abstract
The estimation of distances and angles is a routine part of an orthopedic surgical procedure. However, despite their prevalence, these steps are most often performed manually, heavily relying on the surgeon’s skill and experience. To address these issues, this study presents a sensor-equipped [...] Read more.
The estimation of distances and angles is a routine part of an orthopedic surgical procedure. However, despite their prevalence, these steps are most often performed manually, heavily relying on the surgeon’s skill and experience. To address these issues, this study presents a sensor-equipped drill system which enables automatic estimation of the drilling angle and channel length. The angular accuracy and precision of the system were tested over a range of inclination angles and proved to be superior to the manual approach, with mean absolute errors ranging from 1.9 to 4.5 degrees for the manual approach, and from 0.6 to 1.3 degrees with the guided approach. When sensors were used for simultaneous estimation of both the inclination and anteversion angles, the obtained mean absolute errors were 0.35 ± 0.25 and 2 ± 1.33 degrees for the inclination and anteversion angles, respectively. Regarding channel length estimation, using measurements obtained with a Vernier caliper as a reference, the mean absolute error was 0.33 mm and the standard deviation of errors was 0.41 mm. The obtained results indicate a high potential of smart drill systems for improvement of accuracy and precision in orthopedic surgical procedures, enabling better patient clinical outcomes. Full article
(This article belongs to the Special Issue Medical Devices and Implants, 2nd Edition)
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17 pages, 5085 KiB  
Article
Removal Forces of a Helical Microwire Structure Electrode
by Amelia Howe, Zhanda Chen, Kyle Golobish, Victoria R. Miduri, Derrick Liu, David Valencia, Morgan McGaughey, Emily Szabo, Manfred Franke and Stephan Nieuwoudt
Bioengineering 2024, 11(6), 611; https://doi.org/10.3390/bioengineering11060611 - 13 Jun 2024
Viewed by 472
Abstract
(1) Background: Medical devices, especially neuromodulation devices, are often explanted for a variety of reasons. The removal process imparts significant forces on these devices, which may result in device fracture and tissue trauma. We hypothesized that a device’s form factor interfacing with tissue [...] Read more.
(1) Background: Medical devices, especially neuromodulation devices, are often explanted for a variety of reasons. The removal process imparts significant forces on these devices, which may result in device fracture and tissue trauma. We hypothesized that a device’s form factor interfacing with tissue is a major driver of the force required to remove a device, and we isolated helical and linear electrode structures as a means to study atraumatic removal. (2) Methods: Ductile linear and helical microwire structure electrodes were fabricated from either Gold (Au) or Platinum–Iridium (Pt-Ir, 90-10). Removal forces were captured from synthetic gel models and following chronic implantation in rodent and porcine models. Devices were fully implanted in the animal models, requiring a small incision (<10 mm) and removal via tissue forceps. (3) Results: Helical devices were shown to result in significantly lower maximal removal forces in both synthetic gel and rodent studies compared to their linear counterparts. Chronically (1 yr.), the maximal removal force of helical devices remained under 7.30 N, for which the Platinum–Iridium device’s tensile failure force was 32.90 ± 2.09 N, resulting in a safety factor of 4.50. (4) Conclusions: An open-core helical structure that can freely elongate was shown to result in reduced removal forces both acutely and chronically. Full article
(This article belongs to the Special Issue Medical Devices and Implants, 2nd Edition)
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