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Bioengineering
Special Issues
Advances in Polymer Biotechnology: Sustainable Materials, Biocatalysis, and Industrial Applications
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Advances in Polymer Biotechnology: Sustainable Materials, Biocatalysis, and Industrial Applications

A special issue of Bioengineering (ISSN 2306-5354). This special issue belongs to the section "Biochemical Engineering".

Deadline for manuscript submissions: closed (31 March 2026) | Viewed by 991

Special Issue Editors

Prof. Dr. José Cleiton Sousa dos Santos

E-Mail Website
Guest Editor
Institute of Engineering and Sustainable Development, University of International Integration of the Afro-Brazilian Lusophony, Redenção 62790-970, Brazil
Interests: biocatalysis; enzymes; green chemistry; sustainable polymers; microalgae biorefinery; biofuels; industrial biotechnology
Special Issues, Collections and Topics in MDPI journals
Dr. Leonardo Farias Serafim

E-Mail Website
Guest Editor Assistant
Department of Chemistry, Georgia State University, Atlanta, GA 30302, USA
Interests: polymer biotechnology; biopolymers; polymeric nanomaterials; bio-based materials; industrial applications; materials science; sustainable materials

Special Issue Information

Dear Colleagues,

This Special Issue will focus on recent advances in polymer biotechnology, exploring innovative strategies for the design, synthesis, functionalization, and application of polymers across diverse industrial sectors. The aim is to gather contributions that demonstrate how biotechnology tools, such as enzymes, microbes, and molecular engineering, can be integrated with polymer science to produce sustainable, high-performance, and multifunctional materials.

Key topics will include studies on bio-based and biodegradable polymers, biocatalytic polymer modification, smart and responsive materials, nanocomposites, and polymer-based systems for energy, environmental, and industrial applications. Special attention will be given to studies that bridge experimental, computational, and modeling approaches, as well as translational works that connect academic research with industrial innovation.

We expect to receive original research articles, reviews, short communications, and perspectives covering recent breakthroughs and emerging trends. This Special Issue will serve as a platform to stimulate interdisciplinary collaboration and enhance the visibility of innovative research in polymer biotechnology.

Prof. Dr. José Cleiton Sousa dos Santos
Guest Editor

Dr. Leonardo Farias Serafim
Guest Editor Assistant

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Bioengineering is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • polymer biotechnology
  • sustainable materials
  • biocatalysis
  • bio-based polymers
  • biomanufacturing
  • smart materials
  • polymer nanocomposites
  • industrial biotechnology

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Published Papers (1 paper)

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Research

16 pages, 2448 KB  
Article
Unsaturation-Driven Modulation of Antioxidant and Acetylcholinesterase Inhibitory Activities of Cardanol Derivatives
by Roberta Bussons Rodrigues Valério, Halisson de Souza, Vitor Martins, Katherine Silva, Jane Eire de Manezes, Anderson Chaves, Leonardo F. Serafim, Antônio Vieira-Neto, José Cleiton S. dos Santos and Selene de Morais
Bioengineering 2025, 12(12), 1316; https://doi.org/10.3390/bioengineering12121316 - 1 Dec 2025
Viewed by 802
Abstract
Background: Cardanol, a bioactive alkylphenol obtained from technical cashew nutshell liquid (CNSL), consists of mono-, di-, and tri unsaturated side chain derivatives. These compounds are of increasing interest for their diverse industrial applications. Methods: In this study, three major cardanol components—3-[(8E)-8-pentadecen-1-yl] phenol (C1), [...] Read more.
Background: Cardanol, a bioactive alkylphenol obtained from technical cashew nutshell liquid (CNSL), consists of mono-, di-, and tri unsaturated side chain derivatives. These compounds are of increasing interest for their diverse industrial applications. Methods: In this study, three major cardanol components—3-[(8E)-8-pentadecen-1-yl] phenol (C1), 3-[(8E,11E)-8,11-pentadecadien-1-yl] phenol (C2), and 3-[(8E,11E,14E)-8,11,14-pentadecatrien-1-yl] phenol (C3)—were isolated from CNSL via chromatographic separation. Their structures were confirmed by FTIR and detailed 1H and 13C NMR spectroscopy, with complete carbon and proton assignments reported. Results: Among the three, C3 exhibited the highest antioxidant potential, with a DPPH IC50 value of 0.179 ± 0.005 mg/mL, approximately five times more potent than C1 (IC50 = 1.000 ± 0.200 mg/mL). C3 also showed the highest lethality against Artemia salina (LC50 = 4.118 ± 0.328 mg/mL) and the most pronounced inhibition of acetylcholinesterase (AChE), with a 0.8 cm inhibition zone. Computational studies using molecular docking and molecular dynamics simulations further supported the interaction of these compounds with both the catalytic active site (CAS) and the peripheral anionic site (PAS) of AChE. Conclusions: These results expand our understanding of the chemical composition and potential applications of CNSL. The identified unsaturated alkylphenols, particularly the triene compound, demonstrate promise as sustainable candidates for the development of new materials and pharmaceuticals that combat oxidative stress and neurodegenerative diseases. Full article
(This article belongs to the Special Issue Advances in Polymer Biotechnology: Sustainable Materials, Biocatalysis, and Industrial Applications)
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