New Advances and Insights in Disorders of the Respiratory Muscles
A special issue of Biology (ISSN 2079-7737). This special issue belongs to the section "Medical Biology".
Deadline for manuscript submissions: closed (31 December 2022) | Viewed by 295
Special Issue Editor
Interests: Duchenne muscular dystrophy; dystrophin; cardiomyopathy; heart failure; echocardiography; respiratory; diaphragm; ultrasound; prognosis
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Respiratory muscles and particularly the diaphragm can be affected in patients suffering from chronic diseases, such chronic heart failure, COPD, Pompe disease, amyotrophic lateral sclerosis, muscular dystrophies, and traumatic spinal cord injury. Respiratory muscles are essential to maintain alveolar ventilation. In patients suffering from chronic heart failure, the strength of the respiratory muscles can be reduced, affecting prognosis and exercise tolerance. In COPD, abnormalities in the airways, reduced expiratory flow, and hyperinflation can affect the diaphragm function, this later being a mechanical disadvantage with a decrease in the diaphragmatic curvature and the apposition area. In addition, COPD patients with a decrease in the respiratory mass are at risk of COPD exacerbation. In the neuromuscular field, patients with amyotrophic lateral sclerosis neuromuscular disease, a disease that can affect upper and lower motor neurons, are at risk of respiratory failure. Guillain–Barré syndrome can affect the respiratory muscles with a risk of acute respiratory failure, requiring the introduction of invasive mechanical ventilation in an Intensive Care Unit. In a context of traumatic spinal injury affecting the cervical and the upper thoracic spinal, respiratory muscles can be inefficient with a risk of respiratory failure.
The aims of this Issue will be to develop pathophysiological aspects, new biomarkers, such as respiratory muscle ultrasound, and prognostic factors involved in chronic diseases that affect respiratory muscles.
Dr. Abdallah Fayssoil
Guest Editor
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Keywords
- diaphragm
- ultrasound
- parasternal intercostal muscle
- neuromuscular disorders
- spinal cord injury
- heart failure
- COPD
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