Human Pathogen Infections: Pathogenicity and Immunity

Dear Colleagues,

A human pathogen is a pathogen (microbe or microorganism such as a virus, bacterium, fungus, or parasite, etc.) that causes disease in humans. Human pathogens represent a leading cause of life-threatening infections globally, especially in debilitated patients, and exert a substantial toll on health care resources. Pathogens have evolved multiple mechanisms to combat the host defense (immune system) as they establish infections. These include the capacity of human pathogens to overcome protective host barriers and manipulate host responses. A growing number of human pathogens, bacterial or viral, have been associated with many serious infections resulting from their stress and drug resistance, including biofilm-related infections, which are particularly difficult to treat. However, despite the remarkable acceleration in the understanding of many molecular mechanisms underlying the ability of global human pathogens to establish infection and persist in the host, many key aspects of pathogenicity such as microbial drug resistance, virulence, and manipulation of host responses by pathogens are still not fully understood.

This current issue provides in-depth review articles drafted by international experts tackling different perspectives of human pathogen infections. Their contributions offer insights into aspects related to microbial virulence and drug resistance of both established and emerging human pathogens, as well as models to study their pathogenicity. This Special Issue will focus on original papers covering topics related to "Human Pathogen Infections: Pathogenicity and Immunity" that present advances in those fields. This Special Issue will take an interest in manuscripts that report current data or summarize the current understanding of the human infections caused by microbial pathogens. Interdisciplinary reviews and research articles of various fields, such as microbiology, immunology, cell biology, genetics, are welcome.

Dr. Neeraj Chauhan
Guest Editor

Manuscript Submission Information

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• infectious diseases
• human pathogens
• pathogenesis
• host–pathogen interaction
• host immune system
• autophagy
• antimicrobial resistance
• nutrition and microbial infection
• therapy
• prevention