Recognition of Arboviruses by the Arthropod Immune System
A special issue of Biology (ISSN 2079-7737). This special issue belongs to the section "Immunology".
Deadline for manuscript submissions: closed (31 December 2021) | Viewed by 463
Special Issue Editors
Interests: arbovirology; pathogen-host interactions; immune signalling; molecular entomology; high containment virology
Special Issue Information
Dear Colleagues,
Arthropod-borne viruses (arboviruses) pose a significant threat to human and animal health. Many arboviruses are emerging or re-emerging globally, and some are zoonotic. They are transmitted by the bite of a mosquito, sandfly, biting midge, or tick between humans or animals, where infection causes often mild but sometimes severe disease and death. In the absence of effective vaccines for most arboviruses, research efforts have focused on blocking viral replication and transmission at the stage of the arthropod host. The recent publication of genome sequences for the most medically important arthropod species has enabled us to begin to understand how arboviruses are recognized by the arthropod immune system and which molecular pathways are essential for or detrimental to arbovirus replication in the invertebrate host and onward transmission. Considerable progress in the field of arbovirus–host interactions has been made. However, the complexity of how arboviruses interact with their hosts, with each other, and with the arthropod microbiota under varying environmental conditions and in different arthropod genetic backgrounds demands further investigation into this field. Such knowledge will help identify new avenues for the prevention of arbovirus transmission and spread. For this Special Issue, we thus invite the submission of original research papers and reviews covering all aspects of immune recognition of arboviruses by their arthropod hosts, including both viral and host factors that define their interaction.
Dr. Isabelle DietrichDr. Claudia Rueckert
Guest Editors
Manuscript Submission Information
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Keywords
- arbovirus
- immune signaling
- immune recognition
- arthropod
- vector competence
- microbiota
