Mechanisms of Drug Resistance in Cancer Cells
A special issue of Biology (ISSN 2079-7737). This special issue belongs to the section "Medical Biology".
Deadline for manuscript submissions: 30 April 2025 | Viewed by 85
Special Issue Editors
Interests: medicinal chemistry; anticancer drug discovery; cancer pharmacology; proteomics
Special Issues, Collections and Topics in MDPI journals
Interests: pharmacology; genetics; hematology; oncology
Special Issues, Collections and Topics in MDPI journals
Interests: molecular pharmacology; pain; opioid; natural products; Inflammation
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Drug resistance has been one of the major hurdles that all anti-cancer treatments are facing. The drug resistance mechanisms in cancer cells can be governed by several factors including genetic, epigenetic, proteomic, metabolic, or microenvironmental cues that eventually empower selected cancer cells to survive and proliferate even in very hostile situations, resulting in reduced efficacy of the anti-cancer treatments. Current strategies to overcome drug resistance in cancer cells include new drug discovery, combination therapy and precision immune therapy but are still far from being sufficient. Understanding the drug resistance mechanisms in cancer cells will shed light on the exploration of advanced therapeutic options with better efficacy and the generation of new target-based drugs with improved potency.
Consequently, we are pleased to announce an upcoming Special Issue titled “Mechanisms of Drug Resistance in Cancer Cells” in the Biology journal. The aims of this Special Issue is to explore and understand the mechanisms of drug resistance in cancer cells to withstand the current therapies at the molecular level and also highlight the emerging therapeutic options that may prove to have better potential to challenge the existing problem of drug resistance.
In this Special Issue, original research articles and reviews are welcome. Research areas may include (but not limited to) the following: Factors contributing to drug resistance, Novel approaches to overcome drug resistance, Role of immunity in cancer drug resistance including identifying new immune targets and strategies for overcoming resistance, or biological mechanisms that result from tumor-local or systematic immunity, Role of apoptosis in cancer biology and how cancer cells evade it and Role of microRNAs and lncRNAs related to cancer drug resistance.
I/We look forward to receiving your contributions.
Dr. Xin Chen
Dr. Tuoen Liu
Dr. Wei Lei
Guest Editors
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Keywords
- drug resistance
- mechanisms
- cell growth
- cell proliferation
- efficacy
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