Announcements

15 May 2026
Nutrients 2026—Clinical Nutrition: From Research to Practice—Submission Deadline Extended


Conference:
Nutrients 2026—Clinical Nutrition: From Research to Practice
Date: 22–24 October 2026, CEST, Barcelona, Spain
Website: https://sciforum.net/event/Nutrients2026

We cordially invite you to attend and submit an abstract to this event, organized by MDPI’s Nutrients (ISSN 2072-6643, Impact Factor: 5.8, CiteScore: 10.2). It will take place from 22 to 24 October 2026, CEST, at UAB Casa Convalescencia, Barcelona, Spain.

Conference Chairs:

  • Prof. Dr. Maria Luz Fernandez, University of Connecticut, USA;
  • Prof. Dr. Lluis Serra Majem, University of Las Palmas de Gran Canaria, Spain;
  • Dr. Francisco Jose Perez Cano, University of Barcelona, Spain.

Topics of Interest:
S1. Personalized nutrition based on diet–gene interactions;
S2. Innovations in clinical nutrition;
S3. Novel dietary recommendations for specific chronic diseases;
S4. Understanding the role of microbiota in clinical practice;
S5. The potential role of AI in clinical practice;
S6. Lifestyle and prevention of chronic diseases.

Plenary Speaker Announcement:
We are honored to have Dr. Carlo La Vechia, from the University of Milan ("La Statale"), Italy, as Nutrients 2026 Plenary Speaker for Session 6: Lifestyle and prevention of chronic diseases.

Other renowned researchers from internationally prestigious universities and institutes, including Yale School of Public Health, University of Connecticut, Qatar University, Icahn Medical School of Mount Sinai, and many more, are contributing with us as keynote speakers and scientific committee members.

To view all contributing researchers, please click the following link:
https://sciforum.net/event/Nutrients2026?section=#event_chairs.

Academic Supporters:
Nutrients 2026 is currently supported by and partnered with esteemed universities, institutes, and societies.

To view all supporting organizations and partners, please click on the following link:
https://sciforum.net/event/Nutrients2026?section=#sup_org.

Important Dates:
Deadline for abstract submissions:
24 July 2026;
Notification of acceptance:
14 August 2026;
Deadline for early bird registration:
28 August 2026;
Deadline for covering author registration:
28 August 2026.

Guide for Authors
To submit your abstract, please click on the following link: https://sciforum.net/user/submission/create/1496.

To register for the event, please click on the following link: https://sciforum.net/event/Nutrients2026?section=#registration.

For details regarding abstract submission, poster and slide submission, and publication opportunities, you may refer to the “Instructions for Authors” section below: https://sciforum.net/event/Nutrients2026?section=#instructions.

For any enquiries regarding the event, please contact nutrients2026@mdpi.com.

We look forward to seeing you at Nutrients 2026.

23 July 2025
Nutrients 2026—Clinical Nutrition: From Research to Practice—Open for Submissions


Conference:
Nutrients 2026—Clinical Nutrition: From Research to Practice
Date: 22–24 October 2026, CEST, Barcelona, Spain
Website: https://sciforum.net/event/Nutrients2026

We cordially invite you to attend this event organized by MDPI’s Nutrients (ISSN: 2072-6643, impact factor: 5.0, CiteScore: 9.1). It will take place on 22 to 24 October 2026, CEST, in Barcelona, Spain.

Conference Chairs:

  • Prof. Dr. Maria Luz Fernandez, University of Connecticut, USA;
  • Prof. Dr. Lluis Serra Majem, University of Las Palmas de Gran Canaria, Spain.

The Topics of Interest:

S1. Personalized nutrition based on diet–gene interactions;
S2. Innovations in clinical nutrition;
S3. Novel dietary recommendations for specific chronic diseases;
S4. Understanding the role of microbiota in clinical practice;
S5. The potential role of AI in clinical practice;
S6. Lifestyle and prevention of chronic diseases.

Important Dates

Deadline for abstract submissions: 24 June 2026;
Notification of acceptance: 20 July 2026;
Deadline for early bird registration: 24 July 2026;
Deadline for covering author registration: 24 July 2026.

Guide for Authors

To submit your abstract, please click on the following link: https://sciforum.net/user/submission/create/1496.

To register for the event, please click on the following link: https://sciforum.net/event/Nutrients2026?section=#registration.

For details regarding abstract submission, poster and slide submission, and publication opportunities, you may refer to the “Instructions for Authors” section below: https://sciforum.net/event/Nutrients2026?section=#instructions.

For any enquiries regarding the event, please contact nutrients2026@mdpi.com.

We look forward to seeing you at Nutrients 2026.

15 July 2026
Biomedicines | Selected Editor’s Choice Articles Published in 2025 (VI)


Editor’s Choice Articles are selected based on suggestions from the Academic Editors of Biomedicines (ISSN 2227-9059). The Editors select a small number of published articles that they consider to be particularly interesting to our readers or important in their respective fields of research. As such, you are invited to read our Editor’s Choice Articles, a curated list of high-quality articles published in Biomedicines in 2025. The full list of Editor’s Choice Articles can be viewed via the following link: https://www.mdpi.com/journal/biomedicines/editors_choice.

1. “Endocrine-Disrupting Activities of Flavones on Steroid Receptors: Structural Requirements and Synthesis of Novel Flavone with Improved Estrogenic Activity”
by Steven K. Nordeen, Vijay Kumar, Betty J. Bona, Joshua D. Batson, Donald S. Backos and Michael F. Wempe
Biomedicines 2025, 13(3), 748; https://doi.org/10.3390/biomedicines13030748
Available online: https://www.mdpi.com/2227-9059/13/3/748
Editor's highlight: “This article focuses on the structure and function of flavones, which points to new drug development.

2. “Microbiome and Postbiotics in Skin Health”
by Santosh Kumar Prajapati, Lalitha Lekkala, Dhananjay Yadav, Shalini Jain and Hariom Yadav
Biomedicines 2025, 13(4), 791; https://doi.org/10.3390/biomedicines13040791
Available online: https://www.mdpi.com/2227-9059/13/4/791
Editor's highlight: “Highest overall engagement (views) and citation counts in the dataset. Covers the rapidly evolving microbiome and postbiotics field, which has strong interdisciplinary and translational relevance (dermatology, immunology, therapeutics). As a review, it provides broad insight and synthesis, making it highly valuable.

3. “Perimesencephalic Subarachnoid Hemorrhage Is Not Always a Benign Condition: Hemorrhage Volume as a Predictor for Complications and Clinical Outcome”
by Emily Hoffmann, Công Duy Bùi, Alexandra Valls Chavarria, Michael Müther, Markus Holling, Manfred Musigmann, Max Masthoff, Mostafa Ergawy, Tobias D. Faizy, Christian Paul Stracke et al.
Biomedicines 2025, 13(5), 1061; https://doi.org/10.3390/biomedicines13051061
Available online: https://www.mdpi.com/2227-9059/13/5/1061
Editor's highlight: “Clinically actionable volumetric predictor of complications.”

4. “Experimental Models of Type 2 Diabetes Mellitus Induced by Combining Hyperlipidemic Diet (HFD) and Streptozotocin Administration in Rats: An Integrative Review”
by Ana Karolinne da Silva Brito, Ana Victória da Silva Mendes, Boris Timah Acha, Amanda Suellenn da Silva Santos Oliveira, Joyce Lopes Macedo, Akemi Suzuki Cruzio, Maria das Graças Prianti, Raquel Rodrigues de Abreu, Massimo Lucarini, Alessandra Durazzo et al.
Biomedicines 2025, 13(5), 1158; https://doi.org/10.3390/biomedicines13051158
Available online: https://www.mdpi.com/2227-9059/13/5/1158
Editor's highlight: “Very strong usage metrics (downloads/views) indicating wide interest.
Provides a methodological foundation for preclinical diabetes research, which is broadly applicable.
Integrative reviews are important for standardizing experimental approaches, increasing their long-term value.

5. “Cytokines Meet Phages: A Revolutionary Pathway to Modulating Immunity and Microbial Balance”
by Rossella Cianci, Mario Caldarelli, Paola Brani, Annalisa Bosi, Alessandra Ponti, Cristina Giaroni and Andreina Baj
Biomedicines 2025, 13(5), 1202; https://doi.org/10.3390/biomedicines13051202
Available online: https://www.mdpi.com/2227-9059/13/5/1202
Editor's highlight: “It highlights new evidence of the dynamic and complex relationship between phages and cytokines, suggesting their capacity to regulate inflammation, immune tolerance, and host–pathogen interaction.

6. “Targeting the ZMYM2-ANXA9 Axis with FLT3 Inhibitor G749 Overcomes Oxaliplatin Resistance in Colorectal Cancer”
by Dezheng Lin, Yucheng Xu, Huanmiao Zhan, Yufan Liang, Riyun Liu, Jun Liu, Dandong Luo, Xiaochuan Chen, Jiawei Cai and Yifeng Zou
Biomedicines 2025, 13(5), 1247; https://doi.org/10.3390/biomedicines13051247
Available online: https://www.mdpi.com/2227-9059/13/5/1247
Editor's highlight: “Annexin A9 (ANXA9) has emerged as a prognostic marker in colorectal cancer (CRC); its high expression correlates with chemoresistance and tumor metastasis, and thus with a poor prognosis. However, beyond these correlations, there has been little mechanistic understanding to date. This study describes a mechanism underlying ANXA9 overexpression in resistant cells and identifies the novel ZMYM2–ANXA9 signaling axis, thereby providing fundamental insights into oxaliplatin resistance in CRC. Furthermore, this study identifies ANXA9 as a potential therapeutic target that can be exploited to overcome oxaliplatin resistance.

7. “Preliminary Evaluation of 3D-Printed Alginate/Gelatin Scaffolds for Protein Fast Release as Suitable Devices for Personalized Medicine”
by Benedetta Ghezzi, Ruben Foresti, Luisa Pia Scialoia, Maddalena Botti, Arianna Mersanne, Fulvio Ratto, Francesca Rossi, Chiara Martini, Paolo Perini, Elda Favari et al.
Biomedicines 2025, 13(6), 1365; https://doi.org/10.3390/biomedicines13061365
Available online: https://www.mdpi.com/2227-9059/13/6/1365
Editor's highlight: “Via rapid freeze prototyping (RFP), a Gel and Alg bioink is loaded with different concentrations of apoA-I. Mechanical compressional and tensile properties have been studied, as well as the structural stability and active release from the 3D structure of apoA-I using cholesterol efflux assays.
The biological behavior of HUVEC cells with and without ApoA-I was assessed by proliferation assay, metabolic activity analysis, and fluorescence imaging. The 3D structures presented breakpoint stress values consistent with the mechanical requirements for integration within a DCB, and the ability to effectively promote cholesterol transport in J774 cells. In vitro studies on HUVECs showed that the scaffolds exhibited no cytotoxic effects, leading to increased ATP levels and enhanced metabolic activity over time.

8. “Optimal Fractionation Scheduling for Radiotherapy Treatments with Reinforcement Learning, Tumor Growth Modeling and Outcome Modeling”
by Mélanie Ghislain, Florian Martin, Manon Dausort, Damien Dasnoy-Sumell, Ana Maria Barragan Montero and Benoît Macq
Biomedicines 2025, 13(6), 1367; https://doi.org/10.3390/biomedicines13061367
Available online: https://www.mdpi.com/2227-9059/13/6/1367
Editor's highlight: “Among the papers considered, this manuscript stands out most clearly for conceptual originality and cross-disciplinary appeal. It integrates reinforcement learning with tumor-growth and toxicity outcome modeling to optimize radiotherapy fractionation and reports meaningful reductions in healthy-tissue damage while maintaining tumor-eradication objectives across several disease scenarios.

9. “Crosstalk Between Metabolic Biomarkers and Pulse Wave Analysis in Hypertensive Patients”
by Mirela Baba, Mihaela Ioana Maris, Adina Bucur, Daniela Jianu, Simina Mariana Moroz, Dana Stoian, Constantin Tudor Luca and Ioana Mozos
Biomedicines 2025, 13(7), 1514; https://doi.org/10.3390/biomedicines13071514
Available online: https://www.mdpi.com/2227-9059/13/7/1514
Editor's highlight: “This is an interesting manuscript that describes the results of a study aimed to examine the relationship between lipid profile, various metabolic biomarkers, and pulse wave analysis in patients with hypertension.

10. “Maresin1 Alleviates Ischemia Reperfusion Injury After Lung Transplantation by Inhibiting Ferroptosis via the PKA-Hippo-YAP Signaling Pathway”
by Peng Deng, You Wu, Li Wan, Xiangfu Sun and Quanchao Sun
Biomedicines 2025, 13(7), 1594; https://doi.org/10.3390/biomedicines13071594
Available online: https://www.mdpi.com/2227-9059/13/7/1594
Editor's highlight: “This article identified a brand new ferroptosis-associated pathway.

14 July 2026
Biomedicines | Selected Editor’s Choice Articles Published in 2025 (IV)


Editor’s Choice Articles are selected based on suggestions from the Academic Editors of Biomedicines (ISSN 2227-9059), who highlight a small number of published articles deemed particularly interesting to our readers or important in their respective fields of research. We invite you to read this curated list of high-quality articles published in Biomedicines in 2025 by visiting the full list of Editor’s Choice Articles at the following link: https://www.mdpi.com/journal/biomedicines/editors_choice.

1. “The Role of the Estimated Plasma Volume Variation in Assessing Decongestion in Patients with Acute Decompensated Heart Failure”
by Andreea-Maria Grigore, Mihai Grigore, Ana-Maria Balahura, Gabriela Uscoiu, Ioana Verde, Camelia Nicolae, Elisabeta Bădilă and Adriana-Mihaela Ilieșiu
Biomedicines 2025, 13(1), 88; https://doi.org/10.3390/biomedicines13010088
Available online: https://www.mdpi.com/2227-9059/13/1/88
Editor's highlight: “The paper addresses an important aspect of treatment of acute decompensated heart failure. If verified, the Indirect estimation of plasma volume and its variation are valuable, easily performed, and cost-effective parameters for assessing decongestive treatment in these patients, receiving natriuretic peptides.

2. “PET-Assessed Metabolic Tumor Volume Across the Spectrum of Solid-Organ Malignancies: A Review of the Literature”
by Anusha Agarwal, Chase J. Wehrle, Sangeeta Satish, Paresh Mahajan, Suneel Kamath, Shlomo Koyfman, Wen Wee Ma, Maureen Linganna, Jamak Modaresi Esfeh, Charles Miller et al.
Biomedicines 2025, 13(1), 123; https://doi.org/10.3390/biomedicines13010123
Available online: https://www.mdpi.com/2227-9059/13/1/123
Editor's highlight: “Metabolic tumor volume (MTV) has certain limitations in PET, but MTV as a prognostic factor has great potential and opens an avenue for the future integration of technology into an image-based precision medicine model of care for cancer patients.
This article is a short but focused review and explores the utility and limitations of PET-MTV in various settings of solid-organ malignancy.

3. “From Serendipity to Precision: Integrating AI, Multi-Omics, and Human-Specific Models for Personalized Neuropsychiatric Care”
by Masaru Tanaka
Biomedicines 2025, 13(1), 167; https://doi.org/10.3390/biomedicines13010167
Available online: https://www.mdpi.com/2227-9059/13/1/167
Editor's highlight: “Highly innovative AI–multi-omics–human-model framework.

4. “Advancing Hydrogel-Based 3D Cell Culture Systems: Histological Image Analysis and AI-Driven Filament Characterization”
by Lucio Assis Araujo Neto, Alessandra Maia Freire and Luciano Paulino Silva
Biomedicines 2025, 13(1), 208; https://doi.org/10.3390/biomedicines13010208
Available online: https://www.mdpi.com/2227-9059/13/1/208
Editor's highlight: “This study aimed to use artificial intelligence (AI) in the interpretation of histological cross-section images of hydrogel filaments. Machine learning is used to analyze images by training algorithms on data to recognize patterns and identify objects such as medicine, security, and automation.
Histological cross-sections, longitudinal or transverse, expose layers of tissues or tissue mimetics, which provide crucial information for microscopic analysis. Over six hundred histological cross-section images were obtained and stored in a virtual database. Each hydrogel combination exhibited variations in coloration, and some morphological structures remained consistent.

5. “Nanoparticles for Biomedical Use Derived from Natural Biomolecules: Tannic Acid and Arginine”
by Mehtap Sahiner, Selin S. Suner and Nurettin Sahiner
Biomedicines 2025, 13(1), 209; https://doi.org/10.3390/biomedicines13010209
Available online: https://www.mdpi.com/2227-9059/13/1/209
Editor's highlight: “Poly(tannic acid-co-arginine) (p(TA-co-ARG)) particles at three mole ratios, TA:ARG = 1:1, 1:2, and 1:3, were prepared via a Mannich condensation reaction. The linking molecule between TA and ARG is formaldehyde. The antioxidant capacity of p(TA-co-ARG) particles via gallic acid (GA) and rosmarinic acid (RA) equivalents tests revealed that the particles possess concentration-dependent antioxidant potency and was increased by TA content. The α-glucosidase inhibition of p(TA-co-ARG) particles (2 mg/mL) at 1:1 and 1:2 mole ratios showed enzyme inhibition. p(TA-co-ARG) (1:3 ratio) has significant antibacterial effectiveness against Escherichia coli and Staphylococcus aureus bacteria. This study is quite innovative. Results are ready for clinical applications.

6. “NF-κB-Specific Suppression in Cardiomyocytes Unveils Aging-Associated Responses in Cardiac Tissue”
by Letícia Aparecida Lopes Morgado, Larissa Maria Zacarias Rodrigues, Daiane Cristina Floriano Silva, Bruno Durante da Silva, Maria Claudia Costa Irigoyen and Ana Paula Cremasco Takano
Biomedicines 2025, 13(1), 224; https://doi.org/10.3390/biomedicines13010224
Available online: https://www.mdpi.com/2227-9059/13/1/224
Editor's highlight: “The publication describes investigations of the in vivo role of NF-κB in aging-related cardiac alterations in mice. It suggests that NF-κB plays a critical regulatory role in cardiac aging, influencing both cellular senescence and molecular damage pathways and thus opens new views on the role of NF-κB in aging of the heart. This study may open new ways for treatment of age-related cardiovascular diseases in humans.

7. “Constructing a Glioblastoma Prognostic Model Related to Fatty Acid Metabolism Using Machine Learning and Identifying F13A1 as a Potential Target”
by Yushu Liu, Hui Deng, Ping Song and Mengxian Zhang
Biomedicines 2025, 13(2), 256; https://doi.org/10.3390/biomedicines13020256 
Available online: https://www.mdpi.com/2227-9059/13/2/256
Editor's highlight: “Usually, people would not link F13A1, a coagulation factor, to macrophage-associated tumor development. This article identified how F13A1, which is mainly expressed in macrophage, affects glioblastoma.

8. “A Comprehensive Review of Tubulointerstitial Nephritis and Uveitis (TINU) Syndrome”
by Alexandra Bograd, Arnd Heiligenhaus, Stefan Reuter and Christoph Tappeiner
Biomedicines 2025, 13(2), 300; https://doi.org/10.3390/biomedicines13020300
Available online: https://www.mdpi.com/2227-9059/13/2/300
Editor's highlight: “TINU syndrome is a very rare autoimmune disorder characterized by simultaneous inflammation of both the eye and the kidney. The scientific literature on this condition is therefore not very extensive and is usually divided along highly specialized medical lines between ophthalmology and nephrology. The potential for under- or misdiagnosis, particularly in comparison with other autoimmune diseases, is correspondingly high. This review makes an important contribution to comprehensively presenting this specific clinical picture to a broad readership across disciplinary boundaries.

9. “Novel Insights into the Pathogenesis of Inflammatory Bowel Diseases”
by Valentin Calvez, Pierluigi Puca, Federica Di Vincenzo, Angelo Del Gaudio, Bianca Bartocci, Marco Murgiano, Jacopo Iaccarino, Erfan Parand, Daniele Napolitano, Daniela Pugliese et al.
Biomedicines 2025, 13(2), 305; https://doi.org/10.3390/biomedicines13020305
Available online: https://www.mdpi.com/2227-9059/13/2/305
Editor's highlight: “A comprehensive and well- presented review of the complicated pathophysiology of inflammatory bowel disease.

10. “Mitochondrial Dysfunction in Neurodegenerative Diseases: Mechanisms and Corresponding Therapeutic Strategies”
by Kai Meng, Haocheng Jia, Xiaoqing Hou, Ziming Zhu, Yuguang Lu, Yingying Feng, Jingwen Feng, Yong Xia, Rubin Tan, Fen Cui et al.
Biomedicines 2025, 13(2), 327; https://doi.org/10.3390/biomedicines13020327 
Available online: https://www.mdpi.com/2227-9059/13/2/327
Editor's highlight: “Very broad, timely, high citation potential.

14 July 2026
Biomedicines | Selected Editor’s Choice Articles Published in 2025 (V)


Editor’s Choice Articles are selected based on suggestions from the Academic Editors of Biomedicines (ISSN 2227-9059). The Editors select a small number of published articles that they consider to be particularly interesting to our readers or important in their respective fields of research. As such, you are invited to read our Editor’s Choice Articles, a curated list of high-quality articles published in Biomedicines in 2025. The full list of Editor’s Choice Articles can be viewed via the following link: https://www.mdpi.com/journal/biomedicines/editors_choice.

1. “Probiotic-Derived Metabolites from Lactiplantibacillus plantarum OC01 Reprogram Tumor-Associated Macrophages to an Inflammatory Anti-Tumoral Phenotype: Impact on Colorectal Cancer Cell Proliferation and Migration”
by Beatrice Garavaglia, Letizia Vallino, Alessandra Ferraresi, Angela Amoruso, Marco Pane and Ciro Isidoro
Biomedicines 2025, 13(2), 339; https://doi.org/10.3390/biomedicines13020339
Available online: https://www.mdpi.com/2227-9059/13/2/339
Editor's highlight: “It was selected for its mechanistic exploration of the interaction between microbial metabolites and the tumor immune microenvironment. The study contributes to the emerging field of microbiome-based cancer therapies and highlights potential strategies for modulating anti-tumor immune responses.

2. “The mTOR Signaling Pathway: Key Regulator and Therapeutic Target for Heart Disease”
by Jieyu Wang, Yuxuan Huang, Zhaoxia Wang, Jing Liu, Zhijian Liu, Jinfeng Yang and Zuping He
Biomedicines 2025, 13(2), 397; https://doi.org/10.3390/biomedicines13020397
Available online: https://www.mdpi.com/2227-9059/13/2/397
Editor's highlight: “The selected paper stands out due to its strong scientific relevance and broad biomedical significance, as it addresses heart disease—the leading cause of mortality worldwide—through the lens of the mTOR signaling pathway, a central regulator of key cellular processes. The review provides a comprehensive and well-integrated overview of mTOR structure, function, and regulatory mechanisms, while effectively linking molecular signaling to diverse cardiovascular pathologies. Importantly, it goes beyond descriptive synthesis by highlighting the translational potential of targeting mTOR, discussing therapeutic strategies and pharmacological interventions. This combination of mechanistic depth, clinical relevance, and therapeutic perspective makes the paper particularly impactful and justifies its selection as the strongest among the evaluated works.

3. “Microbiome Integrity Enhances the Efficacy and Safety of Anticancer Drug”
by Alice N. Mafe and Dietrich Büsselberg
Biomedicines 2025, 13(2), 422; https://doi.org/10.3390/biomedicines13020422
Available online: https://www.mdpi.com/2227-9059/13/2/422
Editor's highlight: “Its strength lies in bridging pharmacology, microbiology and oncology into a comprehensive and practical review.”

4. “Integrative Analysis of Gene Expression and Promoter Methylation to Differentiate High-Grade Serous Ovarian Cancer from Benign Tumors”
by Ieva Vaicekauskaitė, Paulina Kazlauskaitė, Rugilė Gineikaitė, Rūta Čiurlienė, Juozas Rimantas Lazutka and Rasa Sabaliauskaitė
Biomedicines 2025, 13(2), 441; https://doi.org/10.3390/biomedicines13020441
Available online: https://www.mdpi.com/2227-9059/13/2/441
Editor's highlight: “A well-written paper on the combination of multiple gene expression or gene promoter methylation biomarkers allowing for the development of an effective biomarker-based diagnostic approach for ovarian cancer. If validated, it may be a valuable addition in the diagnosis of this common tumor.

5. “Metabolic Reprogramming in Gut Microbiota Exposed to Polystyrene Microplastics”
by Jinhua Chi, Jeffrey S. Patterson, Yan Jin, Kyle Joohyung Kim, Nicole Lalime, Daniella Hawley, Freeman Lewis, Lingjun Li, Xuan Wang, Matthew J. Campen et al.
Biomedicines 2025, 13(2), 446; https://doi.org/10.3390/biomedicines13020446
Available online: https://www.mdpi.com/2227-9059/13/2/446
Editor's highlight: “This article shows strong engagement (high downloads and views) and addresses the emerging and important topic of microplastics and their impact on gut microbiota, offering significant environmental and biomedical relevance.”

6. “Targeting Inflammation and Iron Deficiency in Heart Failure: A Focus on Older Adults”
by Daniela Maidana, Andrea Arroyo-Álvarez, Guillermo Barreres-Martín, Andrea Arenas-Loriente, Pedro Cepas-Guillen, Raphaela Tereza Brigolin Garofo, Pedro Caravaca-Pérez and Clara Bonanad
Biomedicines 2025, 13(2), 462; https://doi.org/10.3390/biomedicines13020462
Available online: https://www.mdpi.com/2227-9059/13/2/462
Editor's highlight: “An interesting paper indicating that iron deficiency and inflammation significantly affect heart failure progression, particularly in older adults. Refining diagnostic criteria and exploring innovative therapies are critical to addressing these challenges.

7. “The Journey of Copper-Impregnated Dressings in Wound Healing: From a Medical Hypothesis to Clinical Practice”
by Gadi Borkow and Eyal Melamed
Biomedicines 2025, 13(3), 562; https://doi.org/10.3390/biomedicines13030562
Available online: https://www.mdpi.com/2227-9059/13/3/562
Editor's highlight: “This highly cited review presents a comprehensive translation from hypothesis to clinical application and highlights the clinical and industrial relevance of wound care innovations.

8. “Comparative Analysis of Proximal Tubule Cell Sources for In Vitro Studies of Renal Proximal Tubule Toxicity”
by Courtney Sakolish, Han-Hsuan D. Tsai, Hsing-Chieh Lin, Piyush Bajaj, Remi Villenave, Stephen S. Ferguson, Jason P. Stanko, Richard A. Becker, Philip Hewitt and Weihsueh A. Chiu
Biomedicines 2025, 13(3), 563; https://doi.org/10.3390/biomedicines13030563
Available online: https://www.mdpi.com/2227-9059/13/3/563
Editor's highlight: “A comprehensive study with clear toxicity analysis, including 12 drugs for the treatment of a wide range of RPTEC sources. The results are encouraging for studies on various sources of RPTEC.

9. “Applying Wearable Sensors and Machine Learning to the Diagnostic Challenge of Distinguishing Parkinson’s Disease from Other Forms of Parkinsonism”
by Rana M. Khalil, Lisa M. Shulman, Ann L. Gruber-Baldini, Stephen G. Reich, Joseph M. Savitt, Jeffrey M. Hausdorff, Rainer von Coelln and Michael P. Cummings
Biomedicines 2025, 13(3), 572; https://doi.org/10.3390/biomedicines13030572
Available online: https://www.mdpi.com/2227-9059/13/3/572
Editor's highlight: “Strong translational digital-biomarker angle and focus on data/code visibility.

10. “Sonidegib Inhibits the Adhesion of Acute Myeloid Leukemia to the Bone Marrow in Hypoxia: An Optical Tweezer Study”
by Katarzyna Gdesz-Birula, Sławomir Drobczyński, Krystian Sarat and Kamila Duś-Szachniewicz
Biomedicines 2025, 13(3), 578; https://doi.org/10.3390/biomedicines13030578
Available online: https://www.mdpi.com/2227-9059/13/3/578
Editor's highlight: “Sonidegib is an oral Hedgehog signaling pathway inhibitor used to treat adults with locally advanced basal cell carcinoma (BCC) that has recurred after surgery, radiation, or oral treatments.
Sonidegib works by targeting the Smoothened (SMO) protein to inhibit cancer cell growth. Acute myeloid leukemia (AML) is a heterogeneous disease highly resistant to chemotherapeutic agents.  Leukemia stem cells (LSCs) can enter a dormant state and avoid apoptosis in the bone marrow (BM) microenvironment, and further bone marrow stromal cells protect leukemia cells by promoting pro-survival signaling pathways and drug resistance. Results showed that sonidegib significantly increased the minimum cell-to-cell adhesion time for leukemic cells to establish adhesive bonds with bone marrow stromal cells, thereby indicating a reduction in their adhesive properties. This study shows that optical tweezers can help to carry out a very illustrative and clear targeted in-vitro study. Additionally, the study showed that sonidegib is particularly effective at hypoxic oxygen concentrations.

10 July 2026
Biomedicines | Hot Papers in the “Microbiology in Human Health and Disease” Section


Microorganisms are an essential part of life on Earth, playing an important role in almost every natural cycle. The “Microbiology in Human Health and Disease” Section focuses on microbiology in human health and diseases, including infectious diseases, the interaction between pathogenic microorganisms and hosts, bacteriology, mycology, virology, and parasitology. The point of view of the Section is that microorganisms and public health are closely intertwined, and that advances in one area will have positive consequences on the other.

1. “Gut–Liver–Pancreas Axis Crosstalk in Health and Disease: From the Role of Microbial Metabolites to Innovative Microbiota Manipulating Strategies”
by Giada Marroncini, Laura Naldi, Serena Martinelli and Amedeo Amedei
Biomedicines 2024, 12(7), 1398; https://doi.org/10.3390/biomedicines12071398
Available online: https://www.mdpi.com/2227-9059/12/7/1398

2. “The Interplay of Nutrition, the Gut Microbiota and Immunity and Its Contribution to Human Disease”
by Samantha L. Dawson, Emma Todd and Alister C. Ward
Biomedicines 2025, 13(2), 329; https://doi.org/10.3390/biomedicines13020329
Available online: https://www.mdpi.com/2227-9059/13/2/329

3. “Fungal Pulmonary Coinfections in COVID-19: Microbiological Assessment, Inflammatory Profiles, and Clinical Outcomes”
by Petrinela Daliu, Iulia Bogdan, Ovidiu Rosca, Monica Licker, Livia Claudia Stanga, Elena Hogea, Delia Berceanu Vaduva and Delia Muntean
Biomedicines 2025, 13(4), 864; https://doi.org/10.3390/biomedicines13040864
Available online: https://www.mdpi.com/2227-9059/13/4/864

4. “Cytokines Meet Phages: A Revolutionary Pathway to Modulating Immunity and Microbial Balance”
by Rossella Cianci, Mario Caldarelli, Paola Brani, Annalisa Bosi, Alessandra Ponti, Cristina Giaroni
and Andreina Bajand
Biomedicines 2025, 13(5), 1202; https://doi.org/10.3390/biomedicines13051202
Available online: https://www.mdpi.com/2227-9059/13/5/1202

5. “Exploring the Microbial Landscape: Gut Dysbiosis and Therapeutic Strategies in Pancreatitis—A Narrative Review”
by Vasile Valeriu Lupu, Roxana Mihaela Bratu, Laura Mihaela Trandafir, Laura Bozomitu, Gabriela Paduraru, Nicoleta Gimiga, Gabriela Ghiga, Lorenza Forna, Ileana Ioniuc, Florin Dumitru Petrariu et al.
Biomedicines 2024, 12(3), 645; https://doi.org/10.3390/biomedicines12030645
Available online: https://www.mdpi.com/2227-9059/12/3/645

6. “Maternal-Foetal/Infant Interactions—Gut Microbiota and Immune Health”
by Ada Maria Adamczak, Alicja Werblińska, Małgorzata Jamka and Jarosław Walkowiak
Biomedicines 2024, 12(3), 490; https://doi.org/10.3390/biomedicines12030490
Available online: https://www.mdpi.com/2227-9059/12/3/490

7. “Malnutrition and Its Influence on Gut sIgA–Microbiota Dynamics”
by Monica Profir, Robert Mihai Enache, Oana Alexandra Roşu, Luciana Alexandra Pavelescu, Sanda Maria Creţoiu and Bogdan Severus Gaspar
Biomedicines 2025, 13(1), 179; https://doi.org/10.3390/biomedicines13010179
Available online: https://www.mdpi.com/2227-9059/13/1/179

8. “Gut Microbiota in Heart Failure—The Role of Inflammation”
by Petros N. Fountoulakis, Panagiotis Theofilis, Panayotis K. Vlachakis, Paschalis Karakasis, Konstantinos Pamporis, Marios Sagris, Yannis Dimitroglou, Panagiotis Tsioufis, Evangelos Oikonomou, Konstantinos Tsioufis et al.
Biomedicines 2025, 13(4), 911; https://doi.org/10.3390/biomedicines13040911
Available online: https://www.mdpi.com/2227-9059/13/4/911

9. “Probiotic-Derived Metabolites from Lactiplantibacillus plantarum OC01 Reprogram Tumor-Associated Macrophages to an Inflammatory Anti-Tumoral Phenotype: Impact on Colorectal Cancer Cell Proliferation and Migration”
by Beatrice Garavaglia, Letizia Vallino, Alessandra Ferraresi, Angela Amoruso, Marco Pane and Ciro Isidoro
Biomedicines 2025, 13(2), 339; https://doi.org/10.3390/biomedicines13020339
Available online: https://www.mdpi.com/2227-9059/13/2/339

10. “Exploring the Relationship between Gut Microbiome Composition and Blood Indole-3-acetic Acid in Hemodialysis Patients”
by Ping-Hsun Wu, Yu-Fang Tseng, Wangta Liu, Yun-Shiuan Chuang, Chi-Jung Tai, Chun-Wei Tung, Kean-Yee Lai, Mei-Chuan Kuo, Yi-Wen Chiu, Shang-Jyh Hwang et al.
Biomedicines 2024, 12(1), 148; https://doi.org/10.3390/biomedicines12010148
Available online: https://www.mdpi.com/2227-9059/12/1/148

To acknowledge the above authors' excellent contributions, we are happy to provide a full waiver to each team of the above publications. We also would like to take this opportunity to thank all the research groups that have submitted to Biomedicines (ISSN 2227-9059). We would appreciate it if you would circulate this document among your colleagues and networks. Furthermore, the following opportunities for collaboration may be of interest to you:

Submitting a manuscript:
This Section is currently open for submissions. Papers may be submitted via the following link: https://www.mdpi.com/user/manuscripts/upload/?journal=biomedicines.

Joining the Volunteer Reviewer Board:
If you are an active researcher in the field of biomedical research and are interested in joining the Volunteer Reviewer Board of Biomedicines, please do not hesitate to submit your application via the following link: https://susy.mdpi.com/volunteer/profile/edit.

Biomedicines Editorial Office 

10 July 2026
Biomedicines | Hot Papers in the “Gene and Cell Therapy” Section


The “Gene and Cell Therapy” Section publishes reviews and original peer-reviewed papers. This section of Biomedicines aims to rapidly publish contributions on all aspects of the latest research results concerning gene and cell therapy. We encourage submissions of manuscripts that provide novel and mechanistic insights, including but not limited to gene transfer; vector development and design; autologous and allogeneic cell therapies (hematopoietic and mesenchymal stem cell therapies); the development of genes, peptides, proteins, oligonucleotides, and cell therapies to correct genetic and acquired diseases; vaccine development; preclinical target validation; and other research aspects. In this context, we are pleased to feature some recently published papers from the “Gene and Cell Therapy” Section in Biomedicines (ISSN 2227-9059), which will provide valuable insights into this exciting field.

1. “Advances and Challenges in the Pursuit of Disease-Modifying Osteoarthritis Drugs: A Review of 2010–2024 Clinical Trials”
by Mckenzie D. Brandt, Jason B. Malone and Thomas J. Kean
Biomedicines 2025, 13(2), 355; https://doi.org/10.3390/biomedicines13020355
Available online: https://www.mdpi.com/2227-9059/13/2/355

2. “Scientific Advancements in Gene Therapies: Opportunities for Global Regulatory Convergence”
by Jimi Olaghere, David A. Williams, Jeremy Farrar, Hildegard Büning, Cecelia Calhoun, Tony Ho, Maneesha S. Inamdar, David Liu, Julie Makani, Anouck Coulange Zavarro et al.
Biomedicines 2025, 13(3), 758; https://doi.org/10.3390/biomedicines13030758
Available online: https://www.mdpi.com/2227-9059/13/3/758

3. “Novel Interventions on Comorbidities in Patients with Fetal Alcohol Spectrum Disorder (FASD): An Integrative Review”
by Vicente Andreu-Fernández, Nunzia La Maida, Maribel Marquina, Afrouz Mirahi, Oscar García-Algar, Simona Pichini and Adele Minutillo
Biomedicines 2024, 12(3), 496; https://doi.org/10.3390/biomedicines12030496
Available online: https://www.mdpi.com/2227-9059/12/3/496

4. “Pathophysiology in Brain Arteriovenous Malformations: Focus on Endothelial Dysfunctions and Endothelial-to-Mesenchymal Transition
by Jae Yeong Jeong, Adrian E. Bafor, Bridger H. Freeman, Peng R. Chen, Eun S. Park and Eunhee Kim
Biomedicines 2024, 12(8), 1795; https://doi.org/10.3390/biomedicines12081795
Available online: https://www.mdpi.com/2227-9059/12/8/1795

5. “Stem Cell Therapy for Myocardial Infarction Recovery: Advances, Challenges, and Future Directions”
by Nicholas T. Le, Matthew W. Dunleavy, William Zhou, Sumrithbir S. Bhatia, Rebecca D. Kumar, Suyin T. Woo, Gonzalo Ramirez-Pulido, Kaushik S. Ramakrishnan and Ahmed H. El-Hashash
Biomedicines 2025, 13(5), 1209; https://doi.org/10.3390/biomedicines13051209
Available online: https://www.mdpi.com/2227-9059/13/5/1209

6. “The Impacts of Intervertebral Disc Degeneration of the Spine, Alcohol Consumption, Smoking Tobacco Products, and Glycemic Disorders on the Expression Profiles of Neurotrophins-3 and -4”
by Rafał Staszkiewicz, Dorian Gładysz, Dawid Sobański, Filip Bolechała, Edward Golec, Werner Dammermann and Beniamin Oskar Grabarek
Biomedicines 2024, 12(2), 427; https://doi.org/10.3390/biomedicines12020427
Available online: https://www.mdpi.com/2227-9059/12/2/427

7. “Ten-Year Persistence of Biologic Drugs in Psoriasis and Its Relationship with Pharmacogenetic Biomarkers”
by Andrea Rodríguez-Lopez, María Martínez-Sendino, Rocío Prieto-Pérez, Paula Soria-Chacartegui, Eva González-Iglesias, Mario Aparicio-Domínguez, Sonsoles Berenguer-Ruiz, Esteban Daudén and Francisco Abad-Santos
Biomedicines 2025, 13(1), 5; https://doi.org/10.3390/biomedicines13010005
Available online: https://www.mdpi.com/2227-9059/13/1/5

8. “Therapeutic Opportunities in Melanoma Through PRAME Expression”
by Mislav Mokos, Ivana Prkačin, Klara Gaćina, Ana Brkić, Nives Pondeljak and Mirna Šitum
Biomedicines 2025, 13(8), 1988; https://doi.org/10.3390/biomedicines13081988
Available online: https://www.mdpi.com/2227-9059/13/8/1988

9. “Considerations for the Use of Stereotactic Radiosurgery to Treat Large Arteriovenous Malformations”
by Jong Hyun Lim and Myung Ji Kim
Biomedicines 2024, 12(9), 2003; https://doi.org/10.3390/biomedicines12092003
Available online: https://www.mdpi.com/2227-9059/12/9/2003

10. “Adjuvant Immunotherapy in Stage IIB/IIC Melanoma: Current Evidence and Future Directions”
by Ivana Prkačin, Ana Brkić, Nives Pondeljak, Mislav Mokos, Klara Gaćina and Mirna Šitum
Biomedicines 2025, 13(8), 1894; https://doi.org/10.3390/biomedicines13081894
Available online: https://www.mdpi.com/2227-9059/13/8/1894

To acknowledge the above authors' excellent contributions, we are happy to provide a full waiver to each team of the above publications. We also would like to take this opportunity to thank all the research groups that have submitted to Biomedicines (ISSN 2227-9059). We would appreciate it if you would circulate this document among your colleagues and networks. Furthermore, the following opportunities for collaboration may be of interest to you:

Submitting a manuscript:
This “Gene and Cell Therapy” Section is currently open for submissions. Papers may be submitted via the following link: https://www.mdpi.com/user/manuscripts/upload/?journal=biomedicines.

Joining the Volunteer Reviewer Board:
If you are an active researcher in the fields of biomedical research and are interested in joining the Volunteer Reviewer Board of Biomedicines, please do not hesitate to submit your application via the following link: https://susy.mdpi.com/volunteer/profile/edit.

Biomedicines Editorial Office

10 July 2026
Biomedicines | Hot Papers in the “Neurobiology and Clinical Neuroscience” Section


The “Neurobiology and Clinical Neuroscience” Section publishes reviews and original peer-reviewed papers of a high scientific level covering all aspects of the treatment of neurobiology and neurologic diseases. Topics include, but are not limited to neurogenesis, neuroplasticity, neuropharmacology, and neurotherapeutics, in vitro and in vivo responses to neurological diseases, identification of therapeutic targets, evaluation of diagnostic markers, and assessment of therapies for neurological disorders.

1. “Interactions of Oxytocin and Dopamine—Effects on Behavior in Health and Disease”
by Maria Petersson and Kerstin Uvnäs-Moberg
Biomedicines 2024, 12(11), 2440; https://doi.org/10.3390/biomedicines12112440
Available online: https://www.mdpi.com/2227-9059/12/11/2440

2. “Chronic Stress and Headaches: The Role of the HPA Axis and Autonomic Nervous System”
by Aleksandar Sic, Mark Bogicevic, Nebojsa Brezic, Clara Nemr and Nebojsa Nick Knezevic
Biomedicines 2025, 13(2), 463; https://doi.org/10.3390/biomedicines13020463
Available online: https://www.mdpi.com/2227-9059/13/2/463

3. “Harnessing Brain Plasticity: The Therapeutic Power of Repetitive Transcranial Magnetic Stimulation (rTMS) and Theta Burst Stimulation (TBS) in Neurotransmitter Modulation, Receptor Dynamics, and Neuroimaging for Neurological Innovations”
by Minoo Sharbafshaaer, Giovanni Cirillo, Fabrizio Esposito, Gioacchino Tedeschi and Francesca Trojsi
Biomedicines 2024, 12(11), 2506; https://doi.org/10.3390/biomedicines12112506
Available online: https://www.mdpi.com/2227-9059/12/11/2506

4. “P-tau217 as a Reliable Blood-Based Marker of Alzheimer’s Disease”
by Roy Lai, Brenden Li and Ram Bishnoi
Biomedicines 2024, 12(8), 1836; https://doi.org/10.3390/biomedicines12081836
Available online: https://www.mdpi.com/2227-9059/12/8/1836

5. “A Literature Review: The Mechanisms and Treatment of Neuropathic Pain—A Brief Discussion”
by Renira Rugnath, Casey Orzechowicz, Clayton Newell, Veronica Carullo and Anesh Rugnath
Biomedicines 2024, 12(1), 204; https://doi.org/10.3390/biomedicines12010204
Available online: https://www.mdpi.com/2227-9059/12/1/204

6. “Evaluating p-tau217 and p-tau231 as Biomarkers for Early Diagnosis and Differentiation of Alzheimer’s Disease: A Narrative Review”
by Dorian Julian Jarek, Hubert Mizerka, Jarosław Nuszkiewicz and Karolina Szewczyk-Golec
Biomedicines 2024, 12(4), 786; https://doi.org/10.3390/biomedicines12040786
Available online: https://www.mdpi.com/2227-9059/12/4/786

7. “Cerebral Microbleeds Associate with Brain Endothelial Cell Activation-Dysfunction and Blood–Brain Barrier Dysfunction/Disruption with Increased Risk of Hemorrhagic and Ischemic Stroke”
by Melvin R. Hayden
Biomedicines 2024, 12(7), 1463; https://doi.org/10.3390/biomedicines12071463
Available online: https://www.mdpi.com/2227-9059/12/7/1463

8. “Brain-Derived Neurotrophic Factor (BDNF) as a Marker of Physical Exercise or Activity Effectiveness in Fatigue, Pain, Depression, and Sleep Disturbances: A Scoping Review”
by Nada Lukkahatai, Irvin L. Ong, Chitchanok Benjasirisan and Leorey N. Saligan
Biomedicines 2025, 13(2), 332; https://doi.org/10.3390/biomedicines13020332
Available online: https://www.mdpi.com/2227-9059/13/2/332

9. “The Role of the Cerebellum in Advanced Cognitive Processes in Children”
by Stefano Mastrangelo, Laura Peruzzi, Antonella Guido, Laura Iuvone, Giorgio Attinà, Alberto Romano, Palma Maurizi, Daniela Pia Rosaria Chieffo and Antonio Ruggiero
Biomedicines 2024, 12(8), 1707; https://doi.org/10.3390/biomedicines12081707
Available online: https://www.mdpi.com/2227-9059/12/8/1707

10. “Overview of Novel Antipsychotic Drugs: State of the Art, New Mechanisms, and Clinical Aspects of Promising Compounds”
by Letizia Biso, Marco Carli, Marco Scarselli and Biancamaria Longoni
Biomedicines 2025, 13(1), 85; https://doi.org/10.3390/biomedicines13010085
Available online: https://www.mdpi.com/2227-9059/13/1/85

To acknowledge the above authors’ excellent contributions, we are happy to provide a full waiver to each team of the above publications. We also would like to take this opportunity to thank all the research groups that have submitted to Biomedicines (ISSN 2227-9059). We would appreciate it if you would circulate this document among your colleagues and networks. Furthermore, the following opportunities for collaboration may be of interest to you:

Submitting a manuscript:
This Section is currently open for submissions. Papers may be submitted via the following link:
https://www.mdpi.com/user/manuscripts/upload/?journal=biomedicines.

Joining the Volunteer Reviewer Board:
If you are an active researcher in the fields of biomedical research and are interested in joining the Volunteer Reviewer Board of Biomedicines, please do not hesitate to submit your application via the following link: https://susy.mdpi.com/volunteer/profile/edit.

Biomedicines Editorial Office

8 July 2026
Biomedicines | Hot Papers in the “Molecular Genetics and Genetic Diseases” Section


The Section “Molecular Genetics and Genetic Diseases” covers the basic and translational aspects of human genetic diseases and genomics research, from fundamental molecular investigation to preclinical animal models. In particular, this Section aims to facilitate the rapid publication of innovative research encompassing the genetic basis of human health and disease, as well as the treatment of genetic disorders and heritable or acquired cancers. We welcome submissions that apply new and emerging technologies in the fields of genomics, transcriptomics and bioinformatic tools to advance knowledge in human genetic diseases.

1. “Establishment and Characterization of a Stable Producer Cell Line Generation Platform for the Manufacturing of Clinical-Grade Lentiviral Vectors”
by Ane Arrasate, Igone Bravo, Carlos Lopez-Robles, Ane Arbelaiz-Sarasola, Maddi Ugalde, Martha Lucia Meijueiro, Miren Zuazo, Ana Valero, Soledad Banos-Mateos, Juan Carlos Ramirez et al.
Biomedicines 2024, 12(10), 2265; https://doi.org/10.3390/biomedicines12102265
Available online: https://www.mdpi.com/2227-9059/12/10/2265

2. “Epigenetics of Hypertensive Nephropathy”
by Yize Zhang, Hamidreza Arzaghi, Zhehan Ma, Yasmin Roye and Samira Musah
Biomedicines 2024, 12(11), 2622; https://doi.org/10.3390/biomedicines12112622
Available online: https://www.mdpi.com/2227-9059/12/11/2622

3. “Clinical Genetic Testing for Hearing Loss: Implications for Genetic Counseling and Gene-Based Therapies”
by Nam K. Lee, Kristin M. Uhler, Patricia J. Yoon and Regie Lyn P. Santos-Cortez
Biomedicines 2024, 12(7), 1427; https://doi.org/10.3390/biomedicines12071427
Available online: https://www.mdpi.com/2227-9059/12/7/1427

4. “ABCG2 Gene Expression in Non-Small Cell Lung Cancer”
by Agnieszka Jeleń, Marta Żebrowska-Nawrocka, Mariusz Łochowski, Dagmara Szmajda-Krygier and Ewa Balcerczak
Biomedicines 2024, 12(10), 2394; https://doi.org/10.3390/biomedicines12102394
Available online: https://www.mdpi.com/2227-9059/12/10/2394

5. “Emerging Epigenetic Therapies for the Treatment of Cardiac Fibrosis”
by Nerea Garitano, Laura Pilar Aguado-Alvaro and Beatriz Pelacho
Biomedicines 2025, 13(5), 1170; https://doi.org/10.3390/biomedicines13051170
Available online: https://www.mdpi.com/2227-9059/13/5/1170

6. “Expanding and Enriching the LncRNA Gene–Disease Landscape Using the GeneCaRNA Database”
by Shalini Aggarwal, Chana Rosenblum, Marshall Gould, Shahar Ziman, Ruth Barshir, Ofer Zelig, Yaron Guan-Golan, Tsippi Iny-Stein, Marilyn Safran, Shmuel Pietrokovski et al.
Biomedicines 2024, 12(6), 1305; https://doi.org/10.3390/biomedicines12061305
Available online: https://www.mdpi.com/2227-9059/12/6/1305

7. “Epigenetic Regulation in Wilms Tumor”
by Annabelle Bolitho and Hongbing Liu
Biomedicines 2025, 13(7), 1678; https://doi.org/10.3390/biomedicines13071678
Available online: https://www.mdpi.com/2227-9059/13/7/1678

8. “Increased Phenotype Severity Associated with Splice-Site Variants in a Hungarian Pediatric Neurofibromatosis 1 Cohort: A Retrospective Study”
by Klára Veres, Benedek Nagy, Zsófia Ember, Judit Bene, Kinga Hadzsiev, Márta Medvecz, László Szabó and Zsuzsanna Zsófia Szalai
Biomedicines 2025, 13(1), 146; https://doi.org/10.3390/biomedicines13010146
Available online: https://www.mdpi.com/2227-9059/13/1/146

9. “Selenium and Arsenic Levels, Prevalence of Common Variants of Genes Involved in Their Metabolism, and Psoriasis Disease”
by Tadeusz Dębniak, Piotr Baszuk, Ewa Duchnik, Karolina Rowińska, Emilia Rogoża-Janiszewska, Magdalena Boer, Magdalena Kiedrowicz, Mariola Marchlewicz, Daniel Watola, Martyna Feherpataky et al.
Biomedicines 2024, 12(5), 1082; https://doi.org/10.3390/biomedicines12051082
Available online: https://www.mdpi.com/2227-9059/12/5/1082

10. “Genetic and Epigenetic Components in the Pathogenesis of Adenomyosis and Endometriosis in Adolescents”
by Mario Palumbo, Luigi Della Corte, Mario Ascione, Giuseppe D’Angelo, Dario Colacurci, Giorgio Maria Baldini, Massimiliano Pellicano, Pierluigi Giampaolino and Giuseppe Bifulco
Biomedicines 2025, 13(12), 2988; https://doi.org/10.3390/biomedicines13122988
Available online: https://www.mdpi.com/2227-9059/13/12/2988

To acknowledge the above authors’ excellent contributions, we are happy to provide a full waiver to each team of the above publications. We also would like to take this opportunity to thank all the research groups that have submitted to Biomedicines (ISSN 2227-9059). We would appreciate it if you would circulate this document among your colleagues and networks. Furthermore, the following opportunities for collaboration may be of interest to you:

Submitting a manuscript:
This Section is currently open for submissions. Papers may be submitted via the following link:
https://www.mdpi.com/user/manuscripts/upload/?journal=biomedicines.

Joining the Volunteer Reviewer Board:
If you are an active researcher in the field of biomedicinal research and are interested in joining the Volunteer Reviewer Board of Biomedicines, please do not hesitate to submit your application via the following link: https://susy.mdpi.com/volunteer/profile/edit.

Biomedicines Editorial Office

8 July 2026
Biomedicines | Hot Papers in the “Molecular and Translational Medicine” Section


This Section of Biomedicines (ISSN 2227-9059) aims to cover studies concerning disease pathogenesis at the molecular or physiological level, as well as the basic preclinical, clinical, and translational aspects. We encourage scientists to submit results that have potential for application in human disease, and research obtained from human experimentation or animal models of human disease with the potential to shed light on the underlying causes of human diseases and cancer, to develop future human medicines, medical devices, and diagnostics.

1. “Novel Insights into the Pathogenesis of Inflammatory Bowel Diseases”
by Valentin Calvez, Pierluigi Puca, Federica Di Vincenzo, Angelo Del Gaudio, Bianca Bartocci, Marco Murgiano, Jacopo Iaccarino, Erfan Parand, Daniele Napolitano, Daniela Pugliese et al.
Biomedicines 2025, 13(2), 305; https://doi.org/10.3390/biomedicines13020305
Available online: https://www.mdpi.com/2227-9059/13/2/305

2. “Neutrophil Heterogeneity in Wound Healing”
by Filippo Renò, Corinna Anais Pagano, Monica Bignotto and Maurizio Sabbatini
Biomedicines 2025, 13(3), 694; https://doi.org/10.3390/biomedicines13030694
Available online: https://www.mdpi.com/2227-9059/13/3/694

3. “Artificial Intelligence and ECG: A New Frontier in Cardiac Diagnostics and Prevention”
by Dorota Bartusik-Aebisher, Kacper Rogóż and David Aebisher
Biomedicines 2025, 13(7), 1685; https://doi.org/10.3390/biomedicines13071685
Available online: https://www.mdpi.com/2227-9059/13/7/1685

4. “Ultrasound Assessment in Polycystic Ovary Syndrome Diagnosis: From Origins to Future Perspectives—A Comprehensive Review
by Stefano Di Michele, Anna Maria Fulghesu, Elena Pittui, Martina Cordella, Gilda Sicilia, Giuseppina Mandurino, Maurizio Nicola D’Alterio, Salvatore Giovanni Vitale and Stefano Angioni
Biomedicines 2025, 13(2), 453; https://doi.org/10.3390/biomedicines13020453
Available online: https://www.mdpi.com/2227-9059/13/2/453

5. “Dietary Interventions and Physical Activity as Crucial Factors in the Prevention and Treatment of Metabolic Dysfunction-Associated Steatotic Liver Disease”
by Paweł Rajewski, Jakub Cieściński, Piotr Rajewski, Szymon Suwała, Alicja Rajewska and Maciej Potasz
Biomedicines 2025, 13(1), 217; https://doi.org/10.3390/biomedicines13010217
Available online: https://www.mdpi.com/2227-9059/13/1/217

6. “Impact of Early-Life Microbiota on Immune System Development and Allergic Disorders”
by Norbert Dera, Katarzyna Kosińska-Kaczyńska, Natalia Żeber-Lubecka, Robert Brawura-Biskupski-Samaha, Diana Massalska, Iwona Szymusik, Kacper Dera and Michał Ciebiera
Biomedicines 2025, 13(1), 121; https://doi.org/10.3390/biomedicines13010121
Available online: https://www.mdpi.com/2227-9059/13/1/121

7. “Comparison of Different Molecular Weights of Intra-Articular Hyaluronic Acid Injections for Knee Osteoarthritis: A Level I Bayesian Network Meta-Analysis”
by Filippo Migliorini, Nicola Maffulli, Cornelis Hindriks Nijboer, Gaetano Pappalardo, Mario Pasurka, Marcel Betsch and Joshua Kubach
Biomedicines 2025, 13(1), 175; https://doi.org/10.3390/biomedicines13010175
Available online: https://www.mdpi.com/2227-9059/13/1/175

8. “Gut Microbiota in Psychiatric and Neurological Disorders: Current Insights and Therapeutic Implications”
by Marta Dziedziak, Agata Mytych, Hubert Paweł Szyller, Maria Lasocka, Gabriela Augustynowicz, Joanna Szydziak, Aleksandra Hrapkowicz, Maciej Dyda, Joanna Braksator and Tomasz Pytrus
Biomedicines 2025, 13(9), 2104; https://doi.org/10.3390/biomedicines13092104
Available online: https://www.mdpi.com/2227-9059/13/9/2104

9. “From “Traditional” to “Trained” Immunity: Exploring the Novel Frontiers of Immunopathogenesis in the Progression of Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)”
by Mario Romeo, Alessia Silvestrin, Giusy Senese, Fiammetta Di Nardo, Carmine Napolitano, Paolo Vaia, Annachiara Coppola, Pierluigi Federico, Marcello Dallio and Alessandro Federico
Biomedicines 2025, 13(8), 2004; https://doi.org/10.3390/biomedicines13082004
Available online: https://www.mdpi.com/2227-9059/13/8/2004

10. “Multidrug-Resistant Infections and Metabolic Syndrome: An Overlooked Bidirectional Relationship”
by Carlo Acierno, Riccardo Nevola, Fannia Barletta, Luca Rinaldi, Ferdinando Carlo Sasso, Luigi Elio Adinolfi and Alfredo Caturano
Biomedicines 2025, 13(6), 1343; https://doi.org/10.3390/biomedicines13061343
Available online: https://www.mdpi.com/2227-9059/13/6/1343

To acknowledge the above authors' excellent contributions, we are happy to provide a full waiver to each team of the above publications. We also would like to take this opportunity to thank all the research groups that have submitted to Biomedicines. We would appreciate it if you would circulate this document among your colleagues and network. Furthermore, the following opportunities for collaboration may be of interest to you:

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