Recent Advances in Research on Neuroendocrine Neoplasms and Endocrine Sequelae After Oncological Disease
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Cancer Biology and Oncology".
Deadline for manuscript submissions: 30 April 2026 | Viewed by 12
Special Issue Editor
Interests: pediatric oncology and endocrinology; late effects after pediatric oncological disease; neuro-endocrinology; mechanisms of satiety regulation; diagnostics and treatment of hypothalamic obesity; craniopharyngioma
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Special Issue Information
Dear Colleagues,
Neuroendocrine tumors are a heterogeneous group of rare neoplasms arising from cells of the neuroendocrine system that, though often indolent, can be aggressive and metastatic. One of the authentic features of neuroendocrine tumors is the potential to synthesize and secrete biogenic peptides and hormones, which can cause recognizable clinical hormone syndromes. These functional neuroendocrine tumors are a minority compared to nonfunctional tumors (i.e., 10–40% in a group of pancreatic neuroendocrine tumors), yet they pose significant diagnostic and therapeutic challenges. In any case of functional neuroendocrine tumors, hormonal hypersecretion syndrome leads to excessive morbidity, sometimes more threatening than the malignancy itself.
During the last two decades, therapy-related late effects of cancer treatment have been increasingly recognized, revealing a high cumulative incidence of chronic therapy-associated health problems in long-term cancer survivors. Endocrine complications are among the most frequent effects, which may either occur acutely during initial cancer treatment or develop chronically as a classical late effect.
Despite the advances in diagnostics and therapy, many issues are still unresolved. This Special Issue aims to address the emerging diagnostic and management strategies for neuroendocrine tumors and the improvement or prevention of endocrine sequelae after cancer.
Prof. Dr. Hermann L. Müller
Guest Editor
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Keywords
- neuroendocrine tumors
- endocrinology
- hormones
- cancer
- sequelae
- late effects
- neurogenic tumors
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