Advances in Drug Discovery and Development Using Mass Spectrometry
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Drug Discovery and Development".
Deadline for manuscript submissions: 28 February 2025 | Viewed by 94
Special Issue Editors
Interests: DMPK; proteomics; mass spectrometry; bioanalytics; drug development
Interests: enzymes; proteomics; cancer metabolism; mass spectrometry; drug discovery
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Proteomics-based methods are widely used across the pharmaceutical industry, aiming to identify, characterize, and/or quantify new drug therapeutics. In the early stages of research, exploratory proteomic strategies enable scientists to focus in on significant signaling pathways and identify protein targets crucial to disease states. Later in the process, once potential candidates are identified, efforts to characterize them through assessing critical quality attributes for developability highlight the risks and benefits of potential programs. Once a candidate is considered desirable for the development investment, targeted proteomic approaches can provide the drug’s pharmacokinetics or quantify relevant biomarkers in a highly regulated environment. The proteomics field has had a strong impact, from idea to filing, on the pharmaceutical industry and continues to grow as new innovative techniques are revealed.
Acknowledging the diverse utility of proteomics to pharmaceutical sciences, I invite authors to submit original research and review articles on the topic: Advances in Drug Discovery and Development Using Mass Spectrometry.
Dr. Emily G. Werth
Dr. Amirata Saei Dibavar
Dr. Lin-zhi Chen
Guest Editors
Manuscript Submission Information
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Keywords
- LC/MS
- proteomics
- protein therapeutics
- PTMs
- immunocapture
- CQAs
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