Advances in Cardiac Fibrosis and Inflammation: Molecular Mechanisms and Therapeutic Frontiers

A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Molecular and Translational Medicine".

Deadline for manuscript submissions: 31 December 2024 | Viewed by 58

Special Issue Editor


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Guest Editor
The Brown Foundation Institute of Molecular Medicine, McGovern Medical School, The University of Texas Health Science Center, Houston, TX 77030, USA
Interests: cardiomyopathies; inflammation; CNS disorders; neurodegeneration; neuroprotection; stem cell differentiation; iPSCs; fibrosis; cell death; inflammasomes

Special Issue Information

Dear Colleagues,

Fibrosis and inflammation are key players in the progression of various cardiomyopathies. Understanding these mechanisms is crucial for developing innovative treatments for heart disease. These processes include genetic and epigenetic factors driving cardiac fibrosis, the complex signaling pathways involved in fibroblast activation, and the role of extracellular matrix remodeling. Additionally, inflammatory pathways and inflammasome activation, including the roles of cytokines, chemokines, and immune cells in the heart, are of great interest. 

This Special Issue will also delve into the emerging field of research on exosomes and extracellular vesicles (EVs), which facilitate communication between the heart and other organs. We welcome the submission of articles that explore how EVs contribute to intercellular communication within the heart, their role in spreading fibrotic and inflammatory signals, and their potential as biomarkers and therapeutic delivery vehicles. 

By bringing together these diverse but related topics, this Special Issue will offer a comprehensive overview of the latest advances in the field. Our goal is to include cutting-edge research and thorough reviews that focus on these crucial processes and to inspire new research directions. Ultimately, through this Special Issues, we aim to contribute to the development of better diagnostic tools and treatments for patients suffering from cardiomyopathies.

Dr. Melis Olcum
Guest Editor

Manuscript Submission Information

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Keywords

  • cardiac fibrosis
  • inflammation
  • epigenetics
  • cytokines
  • inflammasomes
  • extracellular vesicles
  • genetic factors
  • cardiomyopathies
  • extracellular matrix
  • fibroblast activation
  • cardiac biomarker
  • immune cells
  • chemokines
  • heart
  • in vivo models
  • in vitro models

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Published Papers

This special issue is now open for submission.
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