Binding between Telocytes, Immune Cells, and Stem Cells
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Immunology and Immunotherapy".
Deadline for manuscript submissions: closed (30 September 2023) | Viewed by 192
Special Issue Editors
Interests: biology; human anatomy; human immunology; gut inflammation; antioxidant activity; bioactive compounds; immunohistochemistry; confocal fluorescence
Special Issues, Collections and Topics in MDPI journals
Interests: comparative anatomy; comparative immunobiology; functional morphology; immunohistochemistry; confocal fluorescence
Interests: bioactive compounds; biology; evolution; internal system of defense; aroma compounds; chemical and sensory analyses; food processing; antioxidant properties
Special Issue Information
Dear Colleagues,
Telocytes are a novel type of interstitial cells named for the first time in 2010 by Popescu and Faussone-Pellegrini (J. Cell. Mol. Med. Vol 14, No 4, 2010 pp. 729–740). Telocytes (TC) are found in many tissues and are mostly located in interstitial layers of organs, and have been identified in many vertebrates, including humans, mice, rats, guinea pigs, chickens, and geese. Recent advances have also suggested the presence of telocytes in invertebrates and fishes. This cell system has been reported as ubiquitous in mammals and interpreted as an important player in innate immunity and tissue regeneration, also contributing to the maintenance of local tissue homeostasis. Telocytes are strategically located in between blood vessels, and close to nerve endings and interstitial cells. Furthermore, TCs appear to be part of stem cell (SC) niches in several organs, such as gut, skeletal muscle, heart, lung, and skin. Increasing evidence suggests a possible implication of TC in regulating the activity of tissue-resident SCs and shaping the SC niche microenvironment, thereby contributing to tissue renewal and repair. Recent evidence shows the involvement of TC in pathology. However, there are still key unanswered questions about these interesting cells. Telocyte research is an exciting field in which we can obtain a better understanding of the mechanisms involved in tissue development and homeostasis.
Prof. Dr. Simona Pergolizzi
Dr. Eugenia Rita Lauriano
Guest Editors
Anthea Miller
Guest Editor Assistant
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Keywords
- telocytes
- immune system
- immunology
- stem cells
- immunohistochemistry
