Mechanisms and Novel Therapeutic Approaches for Gliomas

A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Cancer Biology and Oncology".

Deadline for manuscript submissions: 31 January 2025 | Viewed by 370

Special Issue Editor


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Guest Editor
Department of Brain Sciences, Faculty of Medicine, Imperial College London, London W12 0NN, UK
Interests: glioblastoma; metabolic therapies; immunotherapies; tumour microenvironment; cancer drug discovery

Special Issue Information

Dear Colleagues,

Gliomas, the most common type of primary malignant brain tumour, present significant clinical challenges. This is mainly due to their invasive nature, intratumour heterogeneity, immunosuppressive microenvironment, and the presence of the blood–brain barrier. Little progress has been achieved in glioma treatment over the last few decades, while the main therapeutic options are surgery, radiotherapy, and chemotherapy. Thus, there is an imperative need to deepen our current understanding of glioma mechanisms and develop cutting-edge therapeutic strategies.

This Special Issue aims to cover molecular and cellular glioma mechanisms, including molecular markers, signaling, tumour landscape, cell crosstalk, and immunity, as well as novel therapeutic approaches, such as metabolic therapies, immunotherapies, newly designed and repurposed drugs, and combination treatments.

We also welcome review manuscripts that present recently discovered molecular markers, therapeutic targets, tumour landscape characteristics, or innovative therapies from preclinical studies and clinical trials.

Dr. Maria V. Chatziathanasiadou
Guest Editor

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Keywords

  • glioma
  • molecular mechanisms
  • signaling
  • tumour immunity
  • tumour metabolism
  • tumour microenvironment
  • metabolic therapies
  • immunotherapies
  • combination treatment

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Published Papers

This special issue is now open for submission.
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