Immune and Metabolic Dysregulation in Neurological and Neuropsychiatric Disorders
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Neurobiology and Clinical Neuroscience".
Deadline for manuscript submissions: 28 February 2026 | Viewed by 78
Special Issue Editors
Interests: neurology; pharmacology; immunology; psychiatric disorders
Special Issues, Collections and Topics in MDPI journals
2. University of the Chinese Academy of Sciences, Beijing 100049, China
Interests: brain-body interaction; neuropsychiatric disorders; gut-brain axis
Special Issue Information
Dear Colleagues,
We are pleased to invite you to contribute to this Special Issue titled "Immune and Metabolic Dysregulation in Neurological and Neuropsychiatric Disorders". Immune and metabolic homeostasis is increasingly recognized as being central to brain health, affecting not only neurodegeneration but also a broad range of neuropsychiatric conditions and brain conditions, such as ischemic stroke and traumatic brain injury. Disruptions in immune signaling, energy metabolism, and neuroendocrine regulation have been implicated in diseases such as Alzheimer’s disease, Parkinson’s disease, ischemic stroke, depression, epilepsy, and autism spectrum disorders. Emerging studies also reveal that the gut–brain axis and systemic immune–metabolic crosstalk are crucial in shaping brain function and behavior in healthy and pathological conditions.
This Special Issue aims to highlight cutting-edge research at the intersection of neuroscience, immunology, and metabolism. This Special Issue brings together interdisciplinary contributions to advance our understanding of the underlying mechanisms that are critical in identifying potential risk factors, diagnostic biomarkers, and therapeutic targets for clinical treatment of neurological disorders.
In this Special Issue, original research articles and reviews are welcome. Topics of interest include (but are not limited to) the following research areas:
- Neuroimmune interactions and glial modulation in physiopathological or neurological disorders;
- Gut dysfunction, microbiota, and immune–metabolic signaling in brain disorders;
- Peripheral immune reactions/functions in blood and organs responding to brain injury;
- Neuroendocrine regulation and stress-related brain dysfunction;
- Systemic inflammation and metabolic syndrome in neurodegeneration;
- Multi-omics and systems biology approaches to neuro–immune–metabolic networks;
- Animal models of immune/metabolic perturbation in neurological disorders;
- Clinical studies linking metabolic or immune biomarkers with neuropsychiatric symptoms.
This Special Issue seeks to foster cross-disciplinary dialog and translational insights into neuro–endocrine–immune integration in health and disease. We look forward to receiving your contributions.
Dr. Qingkun Liu
Dr. Xin-An Liu
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomedicines is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- neuroimmune interaction
- neuroinflammation
- metabolic regulation
- gut–brain axis
- microbiome
- neuroendocrine system
- neurodegeneration
- psychiatric disorders
- brain injuries
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