Advancements in Regenerative Medicine: An Integrated Approach Using Nanotechnology and 3D Culture Platforms
A special issue of Biomimetics (ISSN 2313-7673). This special issue belongs to the section "Development of Biomimetic Methodology".
Deadline for manuscript submissions: 30 April 2025 | Viewed by 1111
Special Issue Editor
Interests: modeling and treatment of vascular diseases using stem cells; development of multifunctional biomimetic nanoparticles; development of human blood–brain barrier-on-a-chip; mechanistic relationship of blood–brain barrier disruption and neurodegenerative diseases
Special Issue Information
Dear Colleagues,
Interdisciplinary advancements in tissue engineering and biomedical engineering have integrated various approaches to reconstruct damaged tissues caused by trauma, disease, or genetic disorders. In addition to the conventional regenerative medicine technologies involved in stem cell transplantation, nanotechnologies and 3D cell culture platforms have exhibited their potential to enhance the therapeutic functions of target cells and tissues. These strategies offer the advantage of making biomimetic adjustments to the complex cellular microenvironment to closely resemble that of healthy tissue. The incorporation of such biological, chemical, physical, and mechanical cues enhances the regenerative efficacy by addressing the shortcomings of conventional cell therapies, such as low engraftment and survival rates.
This Special Issue covers the diverse biomimetic nanotechnologies and 3D cell culture platforms that can advance regenerative medicine and stem cell therapy. This Special Issue focuses on a variety of bioactive nanomaterials, such as polymeric or inorganic nanoparticles, as well as exosomes and cell-derived nanovesicles which are emerging alternatives to cell therapies. With regard to 3D cell culture platforms, the scope encompasses traditional domains, such as spheroids and hydrogels, as well as organoids for transplantation. I welcome original articles that present innovative regenerative strategies, as well as reviews and perspectives that elucidate the authors’ valuable insights.
Dr. Jeong-Kee Yoon
Guest Editor
Manuscript Submission Information
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Keywords
- regenerative medicine
- tissue engineering
- nanotechnology
- 3D cell culture
- stem cells
- exosomes
- cell therapy
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