The Interplay between the Immune and Central Nervous Systems in Health and Disease: Current Insights and Future Directions

Dear Colleagues,

The long-held dogma of the central nervous system “immune privilege” has been extensively challenged by research revealing a complex interaction between the immune and central nervous systems. This interaction has become a focal point in current biomedical research, with profound implications for health and disease. Indeed, a growing body of evidence has highlighted the crucial role of neuro-immune crosstalk in shaping both healthy brain functions and the pathophysiology of various disease conditions, ranging from neurodegenerative to psychiatric disorders.

This Special Issue aims to delve into the multifaceted dynamics of neuro-immune communication, exploring its implications on both physiological and pathological processes, while elucidating underlying mechanisms, cellular interactions, and potential therapeutic avenues. In this Special Issue, original research and review articles are welcome.

Dr. Chiara Burgaletto
Guest Editor

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• astrocytes
• immunotherapy
• inflammatory response
• innate and adaptive immunity
• microglia
• neuroinflammation
• neurological diseases
• psychiatric disorders
• therapeutic avenues