Recent Advances in the Understanding of Neuropsychiatric Illnesses

A special issue of Cells (ISSN 2073-4409).

Deadline for manuscript submissions: 15 December 2025 | Viewed by 35

Special Issue Editors

Department of Psychiatry, Johns Hopkins School of Medicine, Baltimore, MD, USA
Interests: intra- and extracellular signaling mechanisms; particularly in the context of neurodegenerative diseases and neuropsychiatric disorders

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Guest Editor
Cellular Neurobiology Laboratory, Johns Hopkins University, School of Medicine, Baltimore, MD, USA
Interests: Parkinson’s disease; obesity; Alzheimer’s disease; neuronal cell death and protein aggregation in neuropsychiatric conditions
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Special Issue Information

Dear Colleagues,

Neuropsychiatric illnesses, encompassing disorders such as schizophrenia, bipolar disorder, Huntington's disease, Alzheimer’s disease, and major depression, pose a significant global health challenge. Despite advances in neuroscience, the molecular and cellular mechanisms driving these conditions—particularly disruptions in intra- and extracellular signaling, synaptic dysfunction, and neuroimmune interactions—remain insufficiently understood. This Special Issue aims to highlight cutting-edge research that bridges basic science with clinical innovation. We invite contributions that offer novel insights into neurodegeneration, neuroinflammation, and circuit-level pathophysiology, as well as studies utilizing emerging tools, such as single-cell omics, CRISPR-based screens, and advanced neuroimaging. Submissions may explore biomarker discovery, therapeutic target validation, or translational strategies designed to improve patient outcomes. By synthesizing multidisciplinary perspectives, this Special Issue strives to catalyze breakthroughs in the understanding and treatment of these complex disorders.

Dr. Junnan Li
Dr. Wanli Smith
Guest Editors

Manuscript Submission Information

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Keywords

  • neuropsychiatric disorders
  • neurodegeneration
  • synaptic plasticity
  • neuroinflammation
  • biomarkers
  • molecular mechanisms
  • translational neuroscience
  • intracellular signaling
  • neuroimaging

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Published Papers

This special issue is now open for submission.
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