Advances in Immunotherapy of Allergic Diseases II

A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cellular Immunology".

Deadline for manuscript submissions: closed (20 January 2023) | Viewed by 3177

Special Issue Editors


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Guest Editor
School of Medicine, University of Cyprus, Nicosia, Cyprus
Interests: allergy; allergen immunotherapy; food allergy; eosinophilic esophagitis; clinical immunology; medical physiology
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Allergy Unit “D. Kalogeromitros”, 2nd Department of Dermatology and Venereology, University General Hospital “ATTIKON”, Athens, Greece
Interests: allergic rhinitis; allergens; immunotherapy; asthma; pediatric allergy; food allergy; venom allergy
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The continuous advancement of biomedical sciences has offered an extreme boost in the diagnosis and therapy of allergic diseases. Allergen immunotherapy (AIT) remains the only causative treatment of IgE-mediated hypersensitivity reactions and represents an example of precision medicine, offered by allergologists. Therapeutical advances such as the introduction of depot extracts for subcutaneous AIT and the use of sublingual immunotherapy have contributed to the safety and efficiency of AIT for a long time. Lately, the emerging intralymphatic route is a novel, much promising approach for AIT. We are also witnessing fast steps in the establishment of food immunotherapy with a variety of proposed protocols, clinical trials, and the approval of the first commercial products for the induction of food tolerance.

After a successful first issue on “Advances in Immunotherapy of Allergic Diseases”, this second Special Issue aims to collect selected reviews and original studies on AIT. We welcome studies and clinical trials on allergens, vaccines, and adjuvants, or on novel desensitization products, papers on new treatment protocols, or on practical issues of AIT. Reviews as well as original papers on the humoral and cellular mechanisms involved in all types of AIT are also welcomed.

We look forward to your contributions to this second Cells Special Edition on AIT.

Dr. Constantinos Pitsios
Dr. Caterina Chliva
Guest Editors

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • allergen immunotherapy
  • allergic rhinitis
  • asthma
  • hymenoptera venom immunotherapy
  • food allergy
  • food tolerance induction

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Published Papers (1 paper)

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17 pages, 613 KiB  
Systematic Review
Molecular Aspects of Allergen-Specific Immunotherapy in Patients with Seasonal Allergic Rhinitis
by Marina Izmailovich, Yuliya Semenova, Gulzada Abdushukurova, Ainur Mukhamejanova, Azhar Dyussupova, Raida Faizova, Meruert Gazaliyeva, Leila Akhvlediani, Natalya Glushkova, Sundetgali Kalmakhanov and Geir Bjørklund
Cells 2023, 12(3), 383; https://doi.org/10.3390/cells12030383 - 20 Jan 2023
Cited by 5 | Viewed by 2830
Abstract
A systematic review and narrative synthesis of publications was undertaken to analyze the role of component-resolved diagnosis technology in identifying polysensitization for the provision of allergen-specific immunotherapy to patients with seasonal allergic rhinitis. A search of publications was carried out in electronic databases [...] Read more.
A systematic review and narrative synthesis of publications was undertaken to analyze the role of component-resolved diagnosis technology in identifying polysensitization for the provision of allergen-specific immunotherapy to patients with seasonal allergic rhinitis. A search of publications was carried out in electronic databases in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. The search helped to identify 568 publications, 12 of which were included in this review. Overall, 3302 patients were enrolled. The major finding was that component-resolved diagnostics change the choice of relevant allergens for allergen-specific immunotherapy in at least 50% of cases. Sensitization to allergen components differs with age, type of disease, and overall disease duration. Patients who had both bronchial asthma and allergic rhinitis were sensitized to a larger number of allergens than patients who had bronchial asthma alone. Full article
(This article belongs to the Special Issue Advances in Immunotherapy of Allergic Diseases II)
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