DNA Methylation in Health and Disease
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cell Nuclei: Function, Transport and Receptors".
Deadline for manuscript submissions: closed (31 July 2019) | Viewed by 19782
Special Issue Editors
Interests: epigenetics; DNA methylation; cancer; cellular heterogeneity; genomics
Interests: induced pluripotent stem cells; epigenetics; hematopoiesis; neurogenesis; early and late stage clinical trials
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear colleagues,
Epigenetic processes determine how cells acquire, maintain, and read memories of past events. Such epigenetic information is maintained at the level of chromatin, where it can influence cellular responses long after memory has been imprinted. DNA methylation represents one of the most well-known and stable epigenetic modifications, with patterns of DNA methylation being faithfully copied through cell divisions. However, during most physiological and pathological processes of adaptation, active changes to the DNA methylation landscape occur, and major efforts are made to document them and understand how they can predict or underlie future responses.
Recent methodological developments for single cell analyses and thedeconvolution of tissue-level DNA methylation patterns now enable us to characterize these changes at an unprecedented resolution and with unsurpassed accuracy. This Special Issue will highlight advances made in this field by summarizing the roles of DNA methylation in both health and diseases as diagnostic and prognostic biomarkers, by reviewing where they are situated in the genome and how methylation changes come about, and by describing how stable changes can mechanistically impact future cellular and organismal processes.
Prof. Dr. Bernard Thienpont
Dr. Giovanni Amabile
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- DNA methylation
- biomarkers
- epigenetics
- cellular heterogeneity
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue polices can be found here.