Cellular and Molecular Mechanisms Induced by Chemical and/or Physical Agents: Focus on Cytological Markers

Dear Colleagues,

In the realm of cellular biology, organisms have evolved diverse response mechanisms to counter the effects of harmful chemical and physical agents. These insults can disrupt various levels of the organism's organization, ranging from the molecular level up to the entire organism.

Principally, these insults can impact cells at different levels. Specifically, cells respond by activating several pathways, such as DNA repair, insult resistance, and xenobiotic detoxification, and put these strategies into place with different actors, enzymes, genes, membrane transporters, mechanisms, and actions. Interestingly, cytoprotection, survival, and cell death mechanisms represent the most frequent mechanisms activated by cells in response to chemical and/or physical agents. In this Special Issue, we welcome the submission of original research papers, full reviews, and short communications that cover the following topics related to cellular and molecular mechanisms induced by chemical and/or physical agents, with a particular focus on markers of damage, survival, or cell death.

• Cytotoxicity markers (at the nuclear, cytoplasmic, and/or cell membrane levels);
• Cellular action mechanisms;
• Cytotoxic effects induced by exogenous changes.

Dr. Roberto Chiarelli
Dr. Flores Naselli
Dr. Fabio Caradonna
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• chemicals toxicity
• model systems
• embryo-cyto-toxicity
• morpho-functional toxicity
• cellular and tissue toxicology
• reproductive toxicity
• reproduction toxicology
• molecular mechanisms
• cell survival
• cell stress
• cell death
• autophagy
• apoptosis
• DNA damage