Immunomodulation by Mesenchymal Stem Cells 2020
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Stem Cells".
Deadline for manuscript submissions: closed (10 April 2021) | Viewed by 29477
Special Issue Editor
Interests: endothelial cells; mesenchymal stromal cells; transplantation; immunology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Mesenchymal stromal or stem cells (MSC) are fibroblast-like multipotent cells that can differentiate into various cell types of mesenchymal origin. Because of their immune properties and differentiation potential, MSC are discussed and tested for the use in tissue regeneration and tolerance induction in transplant medicine. However, the precise mechanisms of action (MOAs) and whether whole MSC or MSC-derived products are needed for the clinical efficacy remain enigmatic. This Special Issue of Cells should provide a state-of-the-art look into the various immunomodulatory properties of MSC, elaborate differences among different sources of MSC, and elucidate MOAs where possible. Current reports about the Good Manufacturing Practice-compliant processing of MSC are also welcome. This should help to optimize personalized cellular therapies with MSC in the future.
Prof. Guenther Eissner
Guest Editor
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Keywords
- Mesenchymal stem cells (MSC)
- immunomodulation
- mechanism of action
- MSC-derived products
- Good Manufacturing Practice (GMP) processing
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Related Special Issue
- Immunomodulation by Mesenchymal Stem Cells in Cells (11 articles)