Bridging Translational Research to the Clinical Management of Metastatic Breast Cancer
A special issue of Cells (ISSN 2073-4409).
Deadline for manuscript submissions: closed (31 December 2021) | Viewed by 4232
Special Issue Editors
2. Department of Medical Oncology, CRO Aviano National Cancer Institute, Aviano, Italy
Interests: translational trials; breast cancer; ctDNA; CTC; circulating biomarkers; endocrine resistance; DNA repair; clinical methodology
Special Issues, Collections and Topics in MDPI journals
Interests: breast cancer
Special Issue Information
Dear Colleagues,
As new multi-omics technologies are emerging as important tools to support precision medicine, their clinical deployment and feasibility are still greatly debated.
As a matter of fact, to be effectively deployed in the clinic, these approaches need to be scalable, reproducible and with optimized turnaround times. Moreover, the resulting data need to be integrated and interpretable by the clinician both to inform the therapeutic strategy and to enable the development of new clinical trial designs that can validate and take full advantage of these technologies.
This Special Issue is aimed at collecting articles of computational, experimental, translational or statistical nature, aiming at optimizing and translating groundbreaking research approaches to the bedside with a significant impact on clinical utility, such as:
- Development and validation of machine learning methods to integrate clinical and multi-omits data for the optimization of clinical workflows;
- Optimization of molecular characterization workflows aimed at clinical scalability;
- New methodological approaches for biomarker-driven clinical trial designs;
- Development of new biomarker-driven healthcare workflows;
- New data science approaches for the real-time integration of multi-omics data streams generated in the clinical environment;
- Integrated pre-clinical and translational studies aimed at developing new treatment or diagnostic approaches.
Dr. Lorenzo Gerratana
Dr. Marta Bonotto
Dr. Angela Toss
Guest Editors
Manuscript Submission Information
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Keywords
- translational
- therapy
- computational
- clinical methodology
- clinical trial design
- biomarker
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