Immune Cells from Pluripotent Stem Cells
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Stem Cells".
Deadline for manuscript submissions: 31 August 2025 | Viewed by 160
Special Issue Editor
2. Director, Cell Therapy 3 Center, CHA Advanced Research Institute, CHA Bundang Medical Center, Sungnam-si 13488, Gyeonggi-do, Republic of Korea
Interests: pluripotent stem cells; hematopoietic stem cells; immune cells; megakaryocytes
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Immune cells exhibit diverse functions such as maintaining homeostasis, defense against pathogens, and regulating immune responses. Immune cells include T cells, B cells, macrophages, natural killer (NK) cells, dendritic cells, and even platelets. These are differentiated from hematopoietic stem cells.
Recently, with the commercialization of CAR-T cells for cancer treatment, interest in immune cell therapy is increasing. However, immune cells isolated from the human body have several limitations, including availability, variability between donors, and challenges in large-scale manufacturing.
Pluripotent stem cells (PSCs) offer a promising alternative due to their unlimited self-renewal and ability to differentiation into various cell types under appropriate conditions. PSCs can also be genetically engineered and differentiated into different immune cell types, potentially overcoming limitations of primary immune cells.
This Special Issue will examine the methods of differentiation and efficacy in vitro and in vivo of immune cells from PSCs.
Prof. Dr. Eunju Kang
Guest Editor
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Keywords
- pluripotent stem cells
- T cells
- B cells
- macrophages
- natural killer (NK) cells
- dendritic cells
- megakaryocytes
- platelets
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