Targeting Oxidative Stress in Cancer
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cellular Pathology".
Deadline for manuscript submissions: closed (20 March 2022) | Viewed by 3347
Special Issue Editors
Interests: reactive oxygen species; oxidative stress; skin cancer; carcinogenesis; cancer signlaing pathway; prostanoid receptor; apoptosis; cell proliferation
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Oxidative stress is defined as the shift of the balance between cellular oxidation and reduction potential towards the oxidizing part, provoked when cellular antioxidant defense capacity is overwhelmed by the massive production of reactive oxygen species (ROS). Excessive ROS production causes oxidative stress, which is implicated in aging and in the pathogenesis of many human disorders, including cancer, obesity, neurodegenerative diseases, and diabetes. Redox imbalance towards pro-oxidant conditions has been considered to be implicated in the pathogenesis of tumor development and progression. In addition, some cellular signaling and metabolic pathways altered due to oxidative and reductive stress have been identified as major contributors to tumorigenesis. Moreover, cancer cells are located in a very complex microenvironment together with stromal components that participate to enhance oxidative stress to promote tumor progression. Understanding the oxidative stress between surrounding cells in the tumor microenvironment can also be a very important topic. This Special Issue aims to propose a possibility for overcoming cancer by targeting oxidative stress in several aspects.
Specifically, this Issue entitled “Targeting Oxidative Stress in Cancer” solicits original research and review articles on topics including the role and contribution of oxidative stress in cancer. This Issue aims to highlight relationships between oxidative stress and tumorigenesis, as well as their role in the pathophysiology and treatment of cancer.
Dr. Kyung-Soo Chun
Dr. Do-Hee Kim
Guest Editors
Manuscript Submission Information
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- oxidative stress
- cancer
- metabolism
- inflammation
- biomarkers
