Biosensors Based on Acoustic Wave Devices

A special issue of Chemosensors (ISSN 2227-9040).

Deadline for manuscript submissions: closed (31 December 2020) | Viewed by 2676

Special Issue Editor


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Guest Editor
Institute for Microelectronics and Microsystems, Italian National Research Council, Rome, Italy
Interests: piezoelectricity; deposition of piezoelectric films; electro-acoustic devices; SAW and BAW propagation; electro-acoustic decives for signal processing and sensor applications

Special Issue Information

Dear Colleagues,

Over the last decade, worldwide interest in biosensors has continuously grown due to the high performances obtained with the use of specific bioreceptors and their wide range of applications in biomedical and healthcare sectors, environmental monitoring, food industry, and so on.

Nevertheless, several challenges remain for obtaining reliable biosensors, in particular to satisfy the demand for implantable devices for the diagnosis and management of metabolic diseases. More recently, advances in nanomaterial synthesis opened a new era for the development of biosensors with enhanced performances. Nano-biosensors exploit the unique properties of nanomaterials and their high specific surface that enables immobilization of an enhanced number of bioreceptors at reduced volume.

In this context, a promising technology platform for the development of biosensors is based on electro-acoustic transduction obtained by piezoelectric materials. This technology ensures a high sensitivity and fast response time typical of electro-acoustic devices and, at the same time, ensures miniaturization, low cost, and, eventually, CMOS compatibility.

The main objective of this Special Issue is to highlight modeling, simulation, and fabrication technologies of biosensors based on different configurations of electro-acoustic devices (delay-lines, resonators, etc.) and to exploit propagation of different modes (i.e., SAW, BAW, Love, SH-SAW, and Lamb). Topics of interest also include strategies for immobilization processes of bioreceptors, eventually in conjunction with functionalized nanomaterials.

This Special Issue aims to provide original research papers and reviews on the state-of-the-art, present-day progress and perspectives within the topics of interest.

Dr. Massimiliano Benetti
Guest Editor

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Keywords

  • Biosensors based on the propagation of acoustic waves: SAW, BAW, Lamb, Love, and SH-SAW
  • biosensors based on delay-lines and resonators (SAW, FBAR, QCM, Contour-Mode Resonator)
  • immobilization strategies of bioreceptors
  • nanomaterials and functionalization strategies
  • acoustophoresis for biosensing applications
  • biosensor arrays

Published Papers (1 paper)

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Research

10 pages, 5338 KiB  
Article
Advances in Electromagnetic Piezoelectric Acoustic Sensor Technology for Biosensor-Based Detection
by Gábor Mészáros, Sanaz Akbarzadeh, Brian De La Franier, Zsófia Keresztes and Michael Thompson
Chemosensors 2021, 9(3), 58; https://doi.org/10.3390/chemosensors9030058 - 23 Mar 2021
Cited by 6 | Viewed by 2336
Abstract
The ultra-high frequency EMPAS (electromagnetic piezoelectric acoustic sensor) device is composed of an electrode-less quartz disc in which shear oscillation is induced by an AC-powered magnetic coil located 30 μm below the substrate. This configuration allows the instigation of high acoustic harmonics (in [...] Read more.
The ultra-high frequency EMPAS (electromagnetic piezoelectric acoustic sensor) device is composed of an electrode-less quartz disc in which shear oscillation is induced by an AC-powered magnetic coil located 30 μm below the substrate. This configuration allows the instigation of high acoustic harmonics (in the region of 49th–53rd), with the resulting enhanced analytical sensitivity for biosensor purposes compared to the conventional thickness-shear mode device. In this paper, we introduce significant improvements to the operation of the system with respect to sensing applications. This includes a new interface program and the capability to measure the acoustic quality factor not available in the prototype version. The enhanced configuration is subject to testing through biosensor detection of surface adsorption of biological macromolecules, which include β-casein, and a gelsolin-actin complex. Full article
(This article belongs to the Special Issue Biosensors Based on Acoustic Wave Devices)
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