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Feature Papers Collection in Molecular Microbiology

A topical collection in Current Issues in Molecular Biology (ISSN 1467-3045). This collection belongs to the section "Molecular Microbiology".

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Editor


E-Mail Website
Collection Editor
Biology Program and Honors College, Oregon State University—Cascades, 1500 SW Chandler Avenue, Bend, OR 97702, USA
Interests: microbial derived products; antimicrobial; bovine herpesviruses; swine and feline caliciviruses; avian paramyxoviruses; metapneumoviruses; orthomyxovirusesprobiotics; genomics-proteomics analyses

Topical Collection Information

Dear Colleagues,

This Topical Collection, entitled “Feature Papers in Molecular Microbiology”, aims to collect high-quality research articles, communications, and review articles on the cutting-edge fields of molecular microbiology. Since the aim of this Topical Collection is to illustrate, through selected works, frontier research in Molecular Microbiology, we encourage the Editorial Board Members of Current Issues in Molecular Biology to contribute Feature Papers reflecting the latest progress in their research field or to invite relevant experts and colleagues to do so.

Topics include, but are not limited to, the following:

  • Virology;
  • Bacteriology;
  • Microbiomes;
  • Veterinary microbiology;
  • Food microbiology;
  • Agricultural microbiology;
  • Infectious diseases;
  • Fungal diseases;
  • Antibacterials and antimicrobials.

Dr. Bruce S. Seal
Collection Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the collection website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Current Issues in Molecular Biology is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • virology
  • bacteriology
  • microbiomes
  • veterinary microbiology
  • food microbiology
  • agricultural microbiology
  • infectious diseases
  • fungal diseases
  • antibacterials and antimicrobials

Published Papers (2 papers)

2024

18 pages, 5410 KiB  
Article
Isolation of a Virulent Clostridium perfringens Strain from Elaphurus davidianus and Characterization by Whole-Genome Sequence Analysis
by Zhao Zhang, Xiao Wang, Siyuan Li, Yuhang Fu, Yan Li, Shah Nawaz, Jing Chen, Guoxiang Yang, Jiakui Li and Daoliang Shi
Curr. Issues Mol. Biol. 2024, 46(7), 7169-7186; https://doi.org/10.3390/cimb46070427 - 8 Jul 2024
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Abstract
Clostridium perfringens (C. perfringens) is an important veterinary pathogen and a noteworthy threat to human and animal health. Recently, there has been a significant rise in the number of moose fatalities caused by this rare, endemic species in China. Currently, there [...] Read more.
Clostridium perfringens (C. perfringens) is an important veterinary pathogen and a noteworthy threat to human and animal health. Recently, there has been a significant rise in the number of moose fatalities caused by this rare, endemic species in China. Currently, there is an increasing trend in conducting whole-genome analysis of C. perfringens strains originating from pigs and chickens, whereas fewer studies have been undertaken on Elaphurus davidianus-originating strains at the whole-genome level. Our laboratory has identified and isolated five C. perfringens type A from affected Elaphurus davidianus. The current study identified the most potent strain of C. perfringens, which originated from Elaphurus davidianus, and sequenced its genome to reveal virulence genes and pathogenicity. Our findings show that strain CX1-4 exhibits the highest levels of phospholipase activity, hemolytic activity, and mouse toxicity compared to the other four isolated C. perfringens type A strains. The chromosome sequence length of the CX1-4 strain was found to be 3,355,389 bp by complete genome sequencing. The current study unveils the genomic characteristics of C. perfringens type A originating from Elaphurus davidianus. It provides a core foundation for further investigation regarding the prevention and treatment of such infectious diseases in Elaphurus davidianus. Full article
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Figure 1

20 pages, 2335 KiB  
Review
Gene Regulatory Mechanism of Mycobacterium Tuberculosis during Dormancy
by Yiduo Liu, Han Li, Dejia Dai, Jiakang He and Zhengmin Liang
Curr. Issues Mol. Biol. 2024, 46(6), 5825-5844; https://doi.org/10.3390/cimb46060348 - 11 Jun 2024
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Abstract
Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb) complex, is a zoonotic disease that remains one of the leading causes of death worldwide. Latent tuberculosis infection reactivation is a challenging obstacle to eradicating TB globally. Understanding the gene regulatory network of Mtb during dormancy [...] Read more.
Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb) complex, is a zoonotic disease that remains one of the leading causes of death worldwide. Latent tuberculosis infection reactivation is a challenging obstacle to eradicating TB globally. Understanding the gene regulatory network of Mtb during dormancy is important. This review discusses up-to-date information about TB gene regulatory networks during dormancy, focusing on the regulation of lipid and energy metabolism, dormancy survival regulator (DosR), White B-like (Wbl) family, Toxin-Antitoxin (TA) systems, sigma factors, and MprAB. We outline the progress in vaccine and drug development associated with Mtb dormancy. Full article
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Figure 1

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