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Current Issues in Molecular Biology publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Molecular Mechanisms and Treatment of Ischemia–Reperfusion Injury

edited by

Jun Kobayashi

submission deadline 30 Apr 2025 | 10 articles | Viewed by 11093 | Submission Open

Keywords: ischemia– reperfusion injury; myocardial infarction; cerebral infarction; renal infarction; crush syndrome; oxidative stress; reactive oxygen species

(This special issue belongs to the Section Molecular Medicine)

Metabolism and Molecular Pathology Related Features in Neurological Diseases

edited by

Rafael Franco

submission deadline 30 Apr 2025 | 4 articles | Viewed by 8345 | Submission Open

Keywords: metabolic dysregulation; neurological disorders; Alzheimer's disease; Parkinson's disease; neuroinflammation

(This special issue belongs to the Section Molecular Medicine)

Reproductive Biology and Germ Cell Development, 2nd Edition

edited by

Huafeng Wang

submission deadline 30 Apr 2025 | 5 articles | Viewed by 7299 | Submission Open

Keywords: reproduction; fertilization; sperm; oocyte; signaling; infertility

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Therapeutic Effects of Natural Bioactive Compounds in the Management of Human Diseases

edited by

Sara Spinelli

Alessia Remigante

and

Rossana Morabito

submission deadline 30 Apr 2025 | 6 articles | Viewed by 7030 | Submission Open

Keywords: natural bioactive compound; human health; chronic diseases; molecular target; oxidative stress; inflammation; cancer; diabetes

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Molecular Research in Vaccinology and Vaccine Development

edited by Attila Farsang

submission deadline 30 Apr 2025 | 4 articles | Viewed by 6134 | Submission Open

Keywords: vaccines; vaccinology; immunology mechanisms; vaccine vectors; gene vaccines; infection; host– pathogen interactions and responses

(This special issue belongs to the Section Molecular Medicine)

Recombinant Proteins for Molecular Biology Research: Technologies and Applications

edited by

Tsutomu Arakawa

and

Yasunari Matsuzaka

submission deadline 30 Apr 2025 | 4 articles | Viewed by 6120 | Submission Open

Keywords: recombinant proteins; vaccine; intra-cellular signaling factors; membrane proteins; drug targets

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Human and Animal Infectious Diseases: Prevention, Diagnosis and Treatment, 2nd Edition

edited by

Sherif T.S. Hassan

submission deadline 30 Apr 2025 | 4 articles | Viewed by 4202 | Submission Open

Keywords: bacterial infections; fungal infections; viral infections; infectious microorganisms; molecular medicine techniques; diagnosis; treatment; and prevention approaches; molecular and physiological investigations; cellular and genetic studies; disease pathogenesis; computational methods; drug design and development

(This special issue belongs to the Section Molecular Medicine)

DNA Damage and Repair in Health and Diseases

edited by

Tomasz Popławski

submission deadline 30 Apr 2025 | 3 articles | Viewed by 3923 | Submission Open

Keywords: DNA damage; DNA repair; DNA repair enzymes; genome stability; oxidative damage; cancers; autoimmune diseases

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Molecular Research of Urological Diseases

edited by Juhyun Shin

submission deadline 30 Apr 2025 | 3 articles | Viewed by 3557 | Submission Open

Keywords: anticancer drugs; apoptosis mechanism; cell death and proliferation; bioinformatics; natural product

(This special issue belongs to the Section Molecular Medicine)

Protein and Bioactive Peptides: Bioactivity, Applications and Health Benefits

edited by

Michele M. Iskandar

submission deadline 30 Apr 2025 | 2 articles | Viewed by 3526 | Submission Open

Keywords: protein; peptides; amino acids; composition; sequence; bioactivity; precursor protein

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Molecular Research on Free Radicals and Oxidative Stress

edited by

Mosharraf Sarker

submission deadline 1 May 2025 | 8 articles | Viewed by 16826 | Submission Open

Keywords: oxidative stress; free radicals; reactive oxygen species (ROS); gene regulation; antioxidants; mitochondrial dysfunction; insulin resistance; inflammation; autophagy

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Molecular Research in Bioactivity of Natural Products, 2nd Edition

edited by

Magdalena Bartnik

and

Wirginia Kukula-Koch

submission deadline 1 May 2025 | 9 articles | Viewed by 9475 | Submission Open

Keywords: molecular research; molecular properties; metabolic pathway; phytochemicals; natural products; apoptosis; bioactivity assessment; chemical composition; therapeutic targets

(This special issue belongs to the Section Bioorganic Chemistry and Medicinal Chemistry)

Tumor Immunology: From Molecular Mechanisms to Treatment

edited by

Deepika Awasthi

submission deadline 1 May 2025 | 1 articles | Viewed by 2198 | Submission Open

Keywords: cellular metabolism; metabolic reprogramming; immunometabolism; tumor microenvironment; immunotherapy; metabolites; immunosuppression; immune cells; tumor cells

(This special issue belongs to the Section Molecular Medicine)

Molecular Mechanisms and Innovative Therapeutic Approaches in Inflammatory Diseases, Pioneering Precision Medicine Solutions

edited by

Hector A. Cabrera-Fuentes

Klaus T. Preissner

and

Elisabeth Deindl

submission deadline 15 May 2025 | 8 articles | Viewed by 4567 | Submission Open

Keywords: inflammatory diseases; autoimmune disorders; cytokine signaling; oxidative stress; therapies

(This special issue belongs to the Section Molecular Medicine)

Genetics and Epigenetics of Neurodegenerative Diseases

edited by

Salvatore Saccone

submission deadline 15 May 2025 | 2 articles | Viewed by 3857 | Submission Open

Keywords: genetics; neurodegenerative diseases; Alzheimer disease

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Technological Advances Around Next-Generation Sequencing Application

edited by

Gaurav Tripathi

submission deadline 20 May 2025 | 3 articles | Viewed by 6474 | Submission Open

Keywords: next-generation sequencing; single-cell sequencing; long-read sequencing; metagenomics; epigenomics; cancer genomics; clinical applications; liquid biopsy; CRISPR-Cas9; precision medicine; personalized healthcare

(This special issue belongs to the Section Bioinformatics and Systems Biology)

Multiple Myeloma: From Molecular Mechanism to Diagnosis and Therapy

edited by

Jari Intra

submission deadline 20 May 2025 | 2 articles | Viewed by 3341 | Submission Open

Keywords: multiple myeloma; blood cancer; immunopathogenesis; biomarker; immunoglobulin

(This special issue belongs to the Section Molecular Medicine)

Novel Drugs and Natural Products Discovery

edited by

Muhammad Khattab

submission deadline 20 May 2025 | 3 articles | Viewed by 2577 | Submission Open

Keywords: natural products; novel drugs; drug design

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Hypersensitivity Pneumonitis: A Complex Lung Disease

edited by

Jari Intra

submission deadline 20 May 2025 | Viewed by 392 | Submission Open

Keywords: hypersensitivity pneumonitis; immunoglobulin; immunopathogenesis; diagnosis; lung disease

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Mutational Landscapes in Cancer Development

edited by

Avisek Majumder

submission deadline 20 May 2025 | Viewed by 192 | Submission Open

Keywords: cancers; genetic mutations; driver mutations; passenger mutations; epigenetics

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Molecular Biology of Viral Replication and Associated Disease Outcomes

edited by Usama Ashraf

submission deadline 21 May 2025 | 4 articles | Viewed by 3350 | Submission Open

Keywords: viruses; replication; immunity; pathogenesis; antivirals; immune modulator

(This special issue belongs to the Section Molecular Microbiology)

Genetics and Natural Bioactive Components in Beverage Plants

edited by Qingsheng Li

submission deadline 31 May 2025 | 4 articles | Viewed by 13084 | Submission Open

Keywords: beverage plants; molecular mechanism; germplasm; breeding; phenotypic changes; metabolites; bioactive components; health benefit

(This special issue belongs to the Section Molecular Plant Sciences)

Role of Natural Products in Inflammatory Diseases

edited by

Chingyuan Wu

submission deadline 31 May 2025 | 4 articles | Viewed by 10374 | Submission Open

Keywords: natural compounds; phytochemicals; bioactivity; IL-1; caspases; inflammasome; proinflammatory cytokines; psoriasis

(This special issue belongs to the Section Bioorganic Chemistry and Medicinal Chemistry)

Drugs: Mechanisms of Action, Molecular Targets and Biological Activities, 2nd Edition

edited by

Pratibha Kumari

submission deadline 31 May 2025 | 6 articles | Viewed by 8580 | Submission Open

Keywords: molecular target; drug repurposing; gene expression; biological activity; phenotype; genotype; allostery

(This special issue belongs to the Section Molecular Pharmacology)

Diabetes and Its Complications: Unraveling the Molecular Landscapes of a Metabolic Conundrum

edited by

Suresh C. Tyagi

submission deadline 31 May 2025 | 5 articles | Viewed by 4744 | Submission Open

Keywords: diabetes mellitus; insulin resistance; beta cell dysfunction; microvascular complications; macrovascular complications; diabetic retinopathy; diabetic nephropathy; diabetic neuropathy; inflammation; glycemic control; therapeutic targets; GLP-1 receptor agonists; SGLT2 inhibitors; biomarkers; metabolic pathways; epigenetics; gut microbiome; chronic hyperglycemia; cardiovascular risk; clinical research

(This special issue belongs to the Section Molecular Medicine)

Molecular Research and Pathological Mechanism of Leukemia

edited by

Sylwia Flis

and Mirosława Koronkiewicz

submission deadline 31 May 2025 | 2 articles | Viewed by 3878 | Submission Open

Keywords: chronic leukemia; acute leukemia; T-cell prolymphocytic leukemia; BCR-ABL1; tyrosine kinase inhibitors; Philadelphia chromosome; biomarkers

(This special issue belongs to the Section Molecular Medicine)

Natural Product Drug Activity and Biomedicine Application

edited by

Anna Makuch-Kocka

submission deadline 31 May 2025 | 3 articles | Viewed by 1652 | Submission Open

Keywords: natural products; signaling pathways; epignetic regulation; cell communication; molecular biology

(This special issue belongs to the Section Molecular Pharmacology)

Molecular Mechanism and Regulation in Neuroinflammation, 2nd Edition

edited by Hung-Pei Tsai

submission deadline 31 May 2025 | 2 articles | Viewed by 1618 | Submission Open

Keywords: microglia; glial cells; cytokines; blood– brain barrier; traumatic brain injury; aging; Alzheimer's disease; parkinson's disease; amyotrophic lateral sclerosis; multiple sclerosis

(This special issue belongs to the Section Molecular Medicine)

Hyperlipidemia and Molecular Mechanism in Human and Animals

edited by

Kyuhyung Choi

submission deadline 31 May 2025 | 1 articles | Viewed by 1388 | Submission Open

Keywords: hyperlipidemia; diabetes mellitus; Cushing’ s disease; pancreatitis; gall bladder mucoceles

(This special issue belongs to the Section Molecular Medicine)

Molecular Biology in Dentistry: Innovations in Diagnosis, Treatment, and Biomaterials

edited by

Maria Maddalena Marrapodi

and Valentina Belli

submission deadline 31 May 2025 | 1 articles | Viewed by 1167 | Submission Open

Keywords: oral microbiome; tissue regeneration; biomimetic materials

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Effects of Nanoparticles on Living Organisms, 3rd Edition

edited by

Yoshitaka Miyamoto

submission deadline 31 May 2025 | Viewed by 279 | Submission Open

Keywords: nanoparticles; particulate matter; medicine; prevention; diagnosis; drug delivery; environment; nanoparticles functionalization; in vitro/in vivo evaluation; 3D model; ADME; toxicity; biomedical applications; respiratory and cardiovascular diseases; immunological; inflammatory; and allergic diseases

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

The Emerging Role of Molecular and Serum Biomarkers in Osteoporosis

edited by

Francesca Salamanna

and

Stefania Pagani

submission deadline 31 May 2025 | Viewed by 213 | Submission Open

Keywords: osteoporosis; biomarkers; PINP; CTX; bone metabolism

(This special issue belongs to the Section Molecular Medicine)

Modulation of Oxidative Stress: A Global Perspective for Climate Change Adaptation

edited by

Tihomir Kovač

and

Tihana Marček

submission deadline 31 May 2025 | Viewed by 147 | Submission Open

Keywords: oxidative stress; modulation; climate change; environmental factors; adaption

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Natural Products in Biomedicine and Pharmacotherapy, 2nd Edition

edited by

Ahmed Ezat El Zowalaty

submission deadline 31 May 2025 | Viewed by 127 | Submission Open

Keywords: natural products; genetic engineering; pharmacotherapy; anticancer; antimicrobials

(This special issue belongs to the Section Bioorganic Chemistry and Medicinal Chemistry)

Complex Molecular Mechanism of Monogenic Diseases: 3rd Edition

edited by

Grzegorz Wegrzyn

submission deadline 10 Jun 2025 | 2 articles | Viewed by 5101 | Submission Open

Keywords: cystic fibrosis; sickle cell disease; duchenne muscular dystrophy; inherited monogenic disease; molecular mechanisms

(This special issue belongs to the Section Molecular Medicine)

Osteoclastogenesis and Osteogenesis: Physiological and Molecular Responses to Xenobiotics and Biomaterials

edited by

Maria Giovanna Rizzo

and

Marika Cordaro

submission deadline 10 Jun 2025 | 3 articles | Viewed by 3680 | Submission Open

Keywords: bone and cartilage biology; physiology; molecular biology; xenobiotics; nutraceuticals; regenerative medicine; biomaterials

(This special issue belongs to the Section Molecular Medicine)

Current Advances in Oxytocin Research

edited by

Claudia Camerino

submission deadline 30 Jun 2025 | 7 articles | Viewed by 14446 | Submission Open

Keywords: oxytocin; thermoregulation; skeletal muscle; obesity; Prader– Willi syndrome

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Advances in Multi-Omics for Functional Genomics Studies and Molecular Breeding

edited by Chen Chen

submission deadline 30 Jun 2025 | 9 articles | Viewed by 10691 | Submission Open

Keywords: sequencing technologies; plant genomics; transcriptomics; proteomics; metabolomics; epigenomics; single-cell sequencing; functional genomics; transformation methods; gene identification

(This special issue belongs to the Section Molecular Plant Sciences)

Advances in Molecular Biology Methods in Hepatology Research

edited by Dileep G. Nair and

Ralf Weiskirchen

submission deadline 30 Jun 2025 | 7 articles | Viewed by 10440 | Submission Open

Keywords: hepatic diseases; molecular biology methods; single-cell genomics; single-cell proteomics; hepatic organoids; biomarkers

(This special issue belongs to the Section Molecular Medicine)

Research on Virus-Induced Cellular and Molecular Responses

edited by

Rudian Zhang

submission deadline 30 Jun 2025 | 6 articles | Viewed by 9202 | Submission Open

Keywords: virus infectivity; infectious diseases; cellular stress; autophagy

(This special issue belongs to the Section Molecular Microbiology)

Natural Product in Skin Inflammation and Barrier Function Damage

edited by

Hsiu-Mei Chiang

submission deadline 30 Jun 2025 | 3 articles | Viewed by 5966 | Submission Open

Keywords: skin inflammation; barrier function damage; natural compounds; antioxidant properties; antiaging

(This special issue belongs to the Section Molecular Medicine)

Molecular Mechanism of HPV’s Involvement in Cancers

edited by Xuesong Wen

submission deadline 30 Jun 2025 | 3 articles | Viewed by 5295 | Submission Open

Keywords: HPV; HPV carcinogenesis; viral interaction; HPV genotyping; head and neck cancer; immune balance; cervical cancer

(This special issue belongs to the Section Molecular Medicine)

Molecular Insights: Mechanisms Underlying the Biological Activities of Natural Products

edited by

Premalatha Balachandran

submission deadline 30 Jun 2025 | 5 articles | Viewed by 4890 | Submission Open

Keywords: natural products; molecular mechanisms; biological activities; pharmacodynamics; drug discovery; therapeutic potential; signaling pathways; target identification; pharmacological properties; bioactive compounds

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Future Challenges of Targeted Therapy of Cancers: 2nd Edition

edited by

Simona Gurzu

submission deadline 30 Jun 2025 | 2 articles | Viewed by 3067 | Submission Open

Keywords: biomarkers; tumor tissue; individualized therapy; gene profile; epithelial– mesenchymal transition; immunotherapy; angiogenesis; metastases; oncology; pathology

(This special issue belongs to the Section Molecular Medicine)

Molecular Insights into Radiation Oncology

edited by Allen Chen

submission deadline 30 Jun 2025 | 2 articles | Viewed by 2948 | Submission Open

Keywords: molecular and cellular radiobiology; radiation physics; DNA damage and repair; radiation response; cancers

(This special issue belongs to the Section Molecular Medicine)

Molecular Mechanisms of Nematodes and Plant Diseases

edited by

Maria De Lurdes Inácio

and

Jorge Miguel Silva Faria

submission deadline 30 Jun 2025 | 1 articles | Viewed by 1958 | Submission Open

Keywords: plants; parasitic nematodes; resistance; susceptibility; resistance breeding; nematodes; phytobiome; nematode– microbial interaction

(This special issue belongs to the Section Molecular Plant Sciences)

Innovative Therapeutics and Biomarkers in Hepatocellular Carcinoma Research

edited by

Alok Raghav

submission deadline 30 Jun 2025 | 2 articles | Viewed by 1915 | Submission Open

Keywords: hepatocellular carcinoma; biomarkers; therapeutics; imaging; artificial intelligence; diagnostics

(This special issue belongs to the Section Molecular Medicine)

Challenges and Advances in Bioinformatics and Computational Biology

edited by Haijun Gong

submission deadline 30 Jun 2025 | 1 articles | Viewed by 1910 | Submission Open

Keywords: bioinformatics; computational biology; genomics; proteomics; metabolomics; multi-omics; machine learning; AI; big data; molecular diagnostics; personalized medicine; data visualization

(This special issue belongs to the Section Bioinformatics and Systems Biology)

Innovations in Marine Biotechnology and Molecular Biology

edited by Huarong Guo

submission deadline 30 Jun 2025 | 2 articles | Viewed by 1896 | Submission Open

Keywords: marine animal; marine algae; marine microorganism; marine biotechnology; molecular biology

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Functional Genomics and Comparative Genomics Analysis in Plants, 3rd Edition

edited by

Quan Zou

, Ran Su and Qiangguo Jin

submission deadline 30 Jun 2025 | 3 articles | Viewed by 1628 | Submission Open

Keywords: de novo genome sequencing; pan-genomic analyses; genome re-sequencing; GWAS analyses; RNA-seq; metabolomics; gene family analyses; plant evolutionary analyses; bioinformatics; database

(This special issue belongs to the Section Molecular Plant Sciences)

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