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Current Issues in Molecular Biology publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Current Advances in Oxytocin Research

edited by

Claudia Camerino

submission deadline 30 Jun 2025 | 8 articles | Viewed by 17668 | Submission Open

Keywords: oxytocin; thermoregulation; skeletal muscle; obesity; Prader– Willi syndrome

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Advances in Molecular Biology Methods in Hepatology Research

edited by Dileep G. Nair and

Ralf Weiskirchen

submission deadline 30 Jun 2025 | 10 articles | Viewed by 14903 | Submission Open

Keywords: hepatic diseases; molecular biology methods; single-cell genomics; single-cell proteomics; hepatic organoids; biomarkers

(This special issue belongs to the Section Molecular Medicine)

Advances in Multi-Omics for Functional Genomics Studies and Molecular Breeding

edited by Chen Chen

submission deadline 30 Jun 2025 | 11 articles | Viewed by 12912 | Submission Open

Keywords: sequencing technologies; plant genomics; transcriptomics; proteomics; metabolomics; epigenomics; single-cell sequencing; functional genomics; transformation methods; gene identification

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Insights: Mechanisms Underlying the Biological Activities of Natural Products

edited by

Premalatha Balachandran

submission deadline 30 Jun 2025 | 6 articles | Viewed by 7708 | Submission Open

Keywords: natural products; molecular mechanisms; biological activities; pharmacodynamics; drug discovery; therapeutic potential; signaling pathways; target identification; pharmacological properties; bioactive compounds

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Natural Compounds: An Adjuvant Strategy in Cancer Management

edited by Monia Cecati and

Arianna Vignini

submission deadline 30 Jun 2025 | 6 articles | Viewed by 4709 | Submission Open

Keywords: cancer; phytochemicals; bioactive compounds; anti-tumor; cancer treatment

(This special issue belongs to the Section Bioorganic Chemistry and Medicinal Chemistry)

The Contribution and Application of Molecular Biology in the Applied Biosciences—Focusing on Medicine, Biomaterials and Tissue Engineering Fields, 2nd Edition

edited by

Ioannis Tsamesidis

and

Evangelia Stalika

submission deadline 30 Jun 2025 | 5 articles | Viewed by 4364 | Submission Open

Keywords: medicine; biomaterials; tissue engineering; molecular biology; patients’ reported outcomes; personalized medicine

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Functional Genomics and Comparative Genomics Analysis in Plants, 3rd Edition

edited by

Quan Zou

, Ran Su and Qiangguo Jin

submission deadline 30 Jun 2025 | 5 articles | Viewed by 3205 | Submission Open

Keywords: de novo genome sequencing; pan-genomic analyses; genome re-sequencing; GWAS analyses; RNA-seq; metabolomics; gene family analyses; plant evolutionary analyses; bioinformatics; database

(This special issue belongs to the Section Molecular Plant Sciences)

Innovations in Marine Biotechnology and Molecular Biology

edited by Huarong Guo

submission deadline 30 Jun 2025 | 4 articles | Viewed by 3041 | Submission Open

Keywords: marine animal; marine algae; marine microorganism; marine biotechnology; molecular biology

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Innovative Therapeutics and Biomarkers in Hepatocellular Carcinoma Research

edited by

Alok Raghav

submission deadline 30 Jun 2025 | 2 articles | Viewed by 2696 | Submission Open

Keywords: hepatocellular carcinoma; biomarkers; therapeutics; imaging; artificial intelligence; diagnostics

(This special issue belongs to the Section Molecular Medicine)

Oral Cancer: Prophylaxis, Etiopathogenesis and Treatment, 2nd Edition

edited by

Violeta Popovici

and

Emma Adriana Ozon

submission deadline 30 Jun 2025 | 2 articles | Viewed by 2210 | Submission Open

Keywords: oral carcinogenesis; biomarkers; cell signaling; natural products; phytochemicals; medicinal plants; essential oils; antimicrobial activity; cytotoxicity; phytotherapy; drug discovery; drug delivery; pharmaceutical formulation

(This special issue belongs to the Section Molecular Medicine)

Molecular Mechanisms of Nematodes and Plant Diseases

edited by

Maria De Lurdes Inácio

and

Jorge Miguel Silva Faria

submission deadline 30 Jun 2025 | 1 articles | Viewed by 2106 | Submission Open

Keywords: plants; parasitic nematodes; resistance; susceptibility; resistance breeding; nematodes; phytobiome; nematode– microbial interaction

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Insights into Industrial Microbiology and Biotechnology

edited by Somasundaram Sivachandiran

submission deadline 30 Jun 2025 | Viewed by 214 | Submission Open

Keywords: industrial microbiology; biotechnology; molecular biology; genetic engineering; systems biology; synthetic biology; biomanufacturing; biofuels; bioplastics; enzyme production; fermentation technology

(This special issue belongs to the Section Molecular Microbiology)

Advances in Phytochemical Research: Molecular Pathways in Health and Disease

edited by

Christiana Charalambous

and

Christiana Neophytou

submission deadline 30 Jun 2025 | Viewed by 212 | Submission Open

Keywords: phytochemicals; molecular mechanisms; cancer signaling pathways; anti-inflammatory properties; anti-oxidant properties; apoptosis; cardiovascular disorders; metabolic syndromes; chemoprevention

(This special issue belongs to the Section Molecular Medicine)

The Interplay Between Immunity, Infection, and Neurocognitive Disorders

edited by

George D. Vavougios

submission deadline 30 Jun 2025 | Viewed by 153 | Submission Open

Keywords: immunity; autoimmunity; cognition; cognitive impairment; infection; neurogeneration; neuroinflammation; computational biology; translational studies; meta-analysis

(This special issue belongs to the Section Molecular Medicine)

Advanced Research on Mechanisms of Neuronal Signaling in Spinal and Peripheral Nerves

edited by Seon-Jin Yoon

submission deadline 30 Jun 2025 | Viewed by 125 | Submission Open

Keywords: molecular neuroscience; molecular marker; drug molecules; antibodies; spinal nerves; peripheral nerves; nerve reanimation; axonal repair; neuroplasticity; animal modeling; immune to nerve cross-talk; inflammation; immune reaction; sensory signal reception; pain signal reception; thermal reception; motor signal; nerve– muscle junction; nerve conduction; spinal cord injury; spinal cord tumor; peripheral nerve tumor; digital/analog sensors for spinal/peripheral nerves; nerve– computer interface; nerve– machine interface; artificial intelligence; artificial spinal cord

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Molecular Strategies for Improved Crop Performance

edited by Maria Oszvald

submission deadline 10 Jul 2025 | Viewed by 168 | Submission Open

Keywords: wheat genome; plant breeding; crop improvement; candidate genes; genetic engineering

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Mechanism and Advances in Gynecological Pathology: From Bench to Bedside

edited by

Ahsanullah Unar

submission deadline 20 Jul 2025 | Viewed by 280 | Submission Open

Keywords: gynecological cancers; molecular pathology; biomarkers; genetic alterations; epigenetics; tumor microenvironment; personalized medicine; targeted therapy; endometriosis; ovarian cancer

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Pharmacological Activities and Mechanisms of Action of Natural Products

edited by

Shining Loo

Antony Kam

and Lee Simon Ming-Yuen

submission deadline 31 Jul 2025 | 13 articles | Viewed by 17483 | Submission Open

Keywords: natural products; pharmacological activity; molecular mechanisms; therapeutic targets; structure– activity relationships; protein– ligand interactions; cell signaling pathways; enzyme inhibition/activation; molecular targets

(This special issue belongs to the Section Bioorganic Chemistry and Medicinal Chemistry)

Molecular Biology in Drug Design and Precision Therapy

edited by

Cristina Manuela Dragoi

Ion-Bogdan Dumitrescu

and

Alina Crenguta Nicolae

submission deadline 31 Jul 2025 | 9 articles | Viewed by 12372 | Submission Open

Keywords: molecular biology; drug design; molecular targets; disease mechanisms; structural biology; computational chemistry; pharmacology; precision medicine; molecular pathways; personalized therapy; drug research

(This special issue belongs to the Section Molecular Medicine)

Infectious Diseases and Molecular Epidemiology: A Focus on Pathogenic Microorganisms

edited by

Haiyan Yang

submission deadline 31 Jul 2025 | 6 articles | Viewed by 12182 | Submission Open

Keywords: infectious disease; malaria; meningitis; pathogene

(This special issue belongs to the Section Molecular Microbiology)

Cellular and Molecular Biology Insights into Neurodegenerative Diseases: From Pathogenesis to Therapeutic Targets

edited by

Michela Pecoraro

and

Silvia Franceschelli

submission deadline 31 Jul 2025 | 5 articles | Viewed by 8837 | Submission Open

Keywords: neurodegenerative disease; oxidative stress; ER stress; mitochondrial stress; corrector; misfolding protein; preoteostasis; neuroblastoma

(This special issue belongs to the Section Molecular Medicine)

Exosomes in Tissue Regeneration and Disease Therapy

edited by

Liang Chen

submission deadline 31 Jul 2025 | 5 articles | Viewed by 7706 | Submission Open

Keywords: exosomes; tiny vesicles; cell-specific proteins; exosome-mediated; human diseases

(This special issue belongs to the Section Molecular Medicine)

Molecular Breeding and Genetics Research in Plants, 2nd Edition

edited by

Shimeles Tilahun

submission deadline 31 Jul 2025 | 7 articles | Viewed by 7303 | Submission Open

Keywords: genetic basis; genomic selection/prediction; molecular breeding; biotic and abiotic stresses; qPCR

(This special issue belongs to the Section Molecular Plant Sciences)

Neuropharmacology and Brain Physiology: From Molecular Mechanisms to Medicines Application

edited by

Gustavo Provensi

submission deadline 31 Jul 2025 | 3 articles | Viewed by 6124 | Submission Open

Keywords: neuropsychopharmacology; neurotransmitters; neuropeptides; receptor proteins; agonist; competitive antagonist; non-competitive antagonist

(This special issue belongs to the Section Molecular Pharmacology)

Molecular Mechanism of Plant Growth, Development and Secondary Metabolism

edited by

Naveed Ahmad

submission deadline 31 Jul 2025 | 4 articles | Viewed by 5368 | Submission Open

Keywords: secondary metabolites; plant defense; signaling and adaptation mechanisms; plant development; genetic and epigenetic regulation; plant physiology

(This special issue belongs to the Section Molecular Plant Sciences)

Radiation-Induced Cellular and Molecular Responses

edited by

Carlo Aprile

submission deadline 31 Jul 2025 | 2 articles | Viewed by 5358 | Submission Open

Keywords: radiation; radiobiology; space radiobiology; heavy ions carcinogenesis; LinearNonTreshold; radionuclide therapy; alpha emitters; beta emitters; radiobiology

(This special issue belongs to the Section Molecular Medicine)

Molecular Mechanisms in Plant Stress Tolerance

edited by

Sajid Ali

submission deadline 31 Jul 2025 | 5 articles | Viewed by 3399 | Submission Open

Keywords: plant stress tolerance; molecular mechanisms; stress-responsive gene; signal transduction pathways; epigenetic modifications; phytohormones (ethylene; ABA; SA; JA); reactive oxygen species (ROS); plant– microbe interactions; microbial plant bio-stimulants; omics approaches (genomics; transcriptomics; proteomics; and metabolomics)

(This special issue belongs to the Section Molecular Plant Sciences)

Effects of Environmental Factors on Cardiovascular Disease: From Molecular Effects to Possible Future Clinic Application

edited by

Angelika Edyta Charkiewicz

submission deadline 31 Jul 2025 | 4 articles | Viewed by 3092 | Submission Open

Keywords: environmental factors; cardiovascular diseases; disease and chronic risk; health status; healthy eating; healthy lifestyle; physical activity; alcohol consumption reduction; tobacco cessation; public health; population health; psychosocial factors; dietary recommendations; nutrient intake; health outcomes

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Molecular Insights into Multifactorial Causes of Insulin Resistance in Obesity

edited by Bogdana Virgolici

submission deadline 31 Jul 2025 | 4 articles | Viewed by 2999 | Submission Open

Keywords: obesity; inflammation; oxidative stress; insulin resistance; caloric restriction

(This special issue belongs to the Section Molecular Medicine)

Epithelial Cancers: Molecular Mechanisms, Diagnostic Innovations, and Therapeutic Advances

edited by

Cristian Scheau

submission deadline 31 Jul 2025 | 1 articles | Viewed by 2633 | Submission Open

Keywords: epithelial cancers; molecular mechanisms; genetic alterations; epigenetics; tumor microenvironment; epithelial-mesenchymal transition; biomarkers; liquid biopsy; imaging technologies; targeted therapies; immunotherapies; personalized medicine; treatment resistance; cancer recurrence; translational research

(This special issue belongs to the Section Molecular Medicine)

Molecular Insights into Pathogenesis and Targeted Therapy of Gynaecological Cancers

edited by

Stergios Boussios

submission deadline 31 Jul 2025 | 2 articles | Viewed by 2217 | Submission Open

Keywords: ovarian cancers; cervical cancers; endometrial cancers; targeted therapy; molecular markers; immunotherapy

(This special issue belongs to the Section Molecular Medicine)

Molecular Mechanisms Underlying Fatty Liver Disease: From Pathogenesis to Treatment, 2nd Edition

edited by Haibo Dong and

Wei Guo

submission deadline 31 Jul 2025 | 3 articles | Viewed by 1729 | Submission Open

Keywords: non-alcoholic fatty liver disease (NAFLD); alcohol-associated liver disease (ALD); lipotoxicity; bile acid metabolism; novel biomarker identification; organelle dysfunction and communication; inflammation and oxidative stress; cell signaling and cell death pathways; lipid metabolism and dysregulation; epigenetic modifications (DNA/RNA/non-coding RNA); therapeutic targets and interventions

(This special issue belongs to the Section Molecular Medicine)

Angiogenesis in Diseases: Molecular Mechanism and Regulation

edited by

Alicia Rodríguez-Barbero

submission deadline 31 Jul 2025 | 1 articles | Viewed by 1443 | Submission Open

Keywords: blood vessels; angiogenic factors; trophic factors; angiogenesis biomarkers; cancers; heart diseases

(This special issue belongs to the Section Molecular Medicine)

Exploring Molecular Pathways in Skin Health and Diseases

edited by

Sullim Lee

submission deadline 31 Jul 2025 | 1 articles | Viewed by 1174 | Submission Open

Keywords: skin health; skin aging; skin disease; molecular pathways; oxidative stress; immune response; inflammatory skin diseases

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

The Molecular Basis of Immunotherapy in Cancer Treatment

edited by Hassan Dastsooz

submission deadline 31 Jul 2025 | 1 articles | Viewed by 1096 | Submission Open

Keywords: immunotherapy; cancer; CAR-T cell therapy; monoclonal antibodies; immunomodulation; cytokines; immune evasion mechanisms

(This special issue belongs to the Section Molecular Medicine)

Molecular Insights into Cancer Biomarkers: Identification and Practical Applications

edited by

Mihaela Chivu-Economescu

submission deadline 31 Jul 2025 | 2 articles | Viewed by 985 | Submission Open

Keywords: cancer biomarkers; liquid biopsy; early detection; progression; prognosis; treatment monitoring

(This special issue belongs to the Section Molecular Medicine)

Molecular Functions of Long Non-Coding RNAs: Implications for Diseases and Therapy

edited by

Bodhisattwa Banerjee

submission deadline 31 Jul 2025 | 1 articles | Viewed by 766 | Submission Open

Keywords: long non-coding RNAs (lncRNAs); gene regulation; molecular mechanisms; chromatin remodeling; epigenetic control; disease pathophysiology; biomarker discovery; therapeutic strategies; translational research

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Molecular and Pharmacological Insights into Bioactive Compounds: Pathways to Therapeutics

edited by

Mosharraf Sarker

and

Talat Nasim

submission deadline 31 Jul 2025 | 1 articles | Viewed by 620 | Submission Open

Keywords: bioactive compounds; natural products; drug discovery; pharmacology; therapeutic pathways; molecular mechanisms; signal transduction; medicinal chemistry; target identification

(This special issue belongs to the Section Molecular Pharmacology)

Tumor Microenvironment: Crosstalk Between Epigenetics, Metabolism and Immunity

edited by

Liang Chen

submission deadline 31 Jul 2025 | 1 articles | Viewed by 577 | Submission Open

Keywords: tumor microenvironment; epigenetic modifications; metabolic reprogramming; immune escape; tumor metastasis; therapeutic resistance

(This special issue belongs to the Section Molecular Medicine)

The Molecular Basis of Genetic and Epigenetic Changes in Cancer

edited by Su Yon Jung

submission deadline 31 Jul 2025 | Viewed by 316 | Submission Open

Keywords: next-generation sequencing (NGS); genetic variation; epigenome; DNA methylation; biomarkers; gene expression; proteomics; cancer(s); prediction; prevention; screening; prognosis; treatment; infection; COVID-19; interaction with the environment; occupational hazard

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Advances in piRNA Biology and Processing: Mechanisms and Applications

edited by

Yicheng Luo

submission deadline 31 Jul 2025 | Viewed by 296 | Submission Open

Keywords: piRNA; Piwi; transposable elements; epigenetics; genetics; development; cancer

(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)

Molecular and Real-World Evidence Research of Respiratory Diseases and Infections, 2nd Edition

edited by

Chingyuan Wu

submission deadline 31 Jul 2025 | Viewed by 235 | Submission Open

Keywords: respiratory diseases; pathogenesis; vaccines; therapies; COVID-19

(This special issue belongs to the Section Molecular Medicine)

Advances in Molecular Therapies and Disease Associations in Diabetes

edited by

Hongbao Cao

and Shaolei Teng

submission deadline 31 Jul 2025 | Viewed by 206 | Submission Open

Keywords: diabetes; molecular therapies; comorbidities; genomics; proteomics; metabolomics; multi-omics; precision medicine

(This special issue belongs to the Section Molecular Medicine)

Autophagy and the Ubiquitin–Proteasome System: Regulators of Protein Homeostasis, Cell Death, and Disease Pathogenesis

edited by

Lei Dong

submission deadline 31 Jul 2025 | 1 articles | Viewed by 200 | Submission Open

Keywords: autophagy; ubiquitin– proteasome system; protein homeostasis; autophagosome; cell death regulation; cancer; Alzheimer's disease

(This special issue belongs to the Section Molecular Medicine)

Design and Synthesis of Bioactive Peptides and Molecular Conjugates for Targeted Drug Delivery

edited by

Ashmeet Singh

submission deadline 31 Jul 2025 | Viewed by 160 | Submission Open

Keywords: peptides; non-covalent synthesis; fluorescent probes; biomaterials; stimuli-responsive; hydrogels; site specific; drug delivery

(This special issue belongs to the Section Bioorganic Chemistry and Medicinal Chemistry)

Omics Technologies and Genomic Studies Unraveling Alzheimer’s Disease Heterogeneity

edited by

Perry G. Ridge

submission deadline 31 Jul 2025 | Viewed by 107 | Submission Open

Keywords: Alzheimer; multi-omics approaches; heterogeneity; genetic loci and biomarkers; neurodegenerative disease research

(This special issue belongs to the Section Bioinformatics and Systems Biology)

Epigenetics and Chromatin Remodeling in Cancer

edited by

Gianluca Tedaldi

submission deadline 31 Jul 2025 | Viewed by 86 | Submission Open

Keywords: epigenetics; chromatin remodeling; DNA methylation; histone modifications; non-coding RNAs; circulating tumor DNA; liquid biopsy; epigenetic therapy

(This special issue belongs to the Section Molecular Medicine)

Phagocytosis in Neurological Disorders: Molecular Mechanisms and Therapeutic Targets

edited by