Molecular Biology of Viral Replication and Associated Disease Outcomes
A special issue of Current Issues in Molecular Biology (ISSN 1467-3045). This special issue belongs to the section "Molecular Microbiology".
Deadline for manuscript submissions: 20 November 2024 | Viewed by 87
Special Issue Editor
Interests: molecular virology; host–virus interaction; viral pathogenesis; viral innate immunology; antivirals; RNA biology; serology of viral infections; virus evolution
Special Issue Information
Dear Colleagues,
I am pleased to invite you to submit articles on molecular insights into viral replication and associated disease outcomes. Viral replication involves a series of intricate steps, beginning with the virus attaching to and entering the host cell, then uncoating its genome, replicating and transcribing its genetic material, synthesizing viral proteins, assembling new virions, and finally releasing these virions to infect new cells. During replication, viruses exhibit diverse strategies depending on their type, such as DNA viruses using a host's nuclear machinery and RNA viruses, frequently relying on specialized viral enzymes like RNA-dependent RNA polymerase. In response to viral replication, disease outcomes vary widely and can range from acute, self-limiting illnesses to chronic and persistent infections. The host immune response plays a decisive role during infections, where innate immunity provides immediate, non-specific defense, whereas adaptive immunity offers a defined, long-term protective response. Understanding these processes is essential for establishing effective vaccines, antiviral therapies, and public health strategies to mitigate the burden of viral diseases in humans and animals.
In this Special Issue, original articles and reviews are welcome. Research may include, but is not limited to, the following:
- Mechanisms of viral ingress and egress from host cells.
- Mechanisms of viral replication (the transcription and translation of viral genes).
- Immunity to viral infections.
- Mechanisms of virus-mediated disease pathogenesis and disease outcomes.
- Therapeutic interventions to inhibit virus replication and mitigate disease outcomes.
I look forward to receiving your contributions.
Dr. Usama Ashraf
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Current Issues in Molecular Biology is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- viruses
- replication
- immunity
- pathogenesis
- antivirals
- immune modulator
