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Advances in Laser-Assisted Techniques for Biomedical Applications
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Advances in Laser-Assisted Techniques for Biomedical Applications

A special issue of Coatings (ISSN 2079-6412). This special issue belongs to the section "Laser Coatings".

Deadline for manuscript submissions: closed (31 December 2023) | Viewed by 5092

Special Issue Editors

Prof. Dr. Roberto Teghil

E-Mail Website
Guest Editor
Università degli Studi della Basilicata, Dipartimento di Scienze, Potenza, Italy
Interests: thin film deposition; laser ablation; ultra-short pulse lasers; plasma techniques; nanotechnologies; ceramic materials
Prof. Dr. Angela De Bonis

E-Mail Website
Guest Editor
Università degli Studi della Basilicata, Dipartimento di Scienze, Potenza, Italy
Interests: thin films and nanotechnology; thin film deposition; optics; laser; solid state physics; physical chemistry; experimental physics; plasma; Raman spectroscopy; femtosecond lasers laser ablation; ultrashort lasers; pulsed laser deposition; laser-induced breakdown spectroscopy; laser ablation in liquids; SERS Photo:
Dr. Mariangela Curcio

E-Mail Website
Guest Editor
Department of Science, University of Basilicata, Potenza, Italy
Interests: physical chemistry; material science; thin films and nanotechnology; thin film deposition; pulsed laser deposition; laser ablation in liquid; microbattery; bioactive materials

Special Issue Information

Dear Colleagues,

Laser assisted techniques have been proven to be versatile and powerful for the preparation, coating and surface modification of alloyed, metallic and polimeric biomedical materials. Selective laser sintering or melting (SLS or SLM) were proposed for the development of bone-like structures that exhibit improved tribological and mechanical properties. Pulsed laser deposition (PLD) has been used to deposit thin ceramic and glasses coatings whose biocompatibility benefits the typical micro-nanostructures of the laser deposited films. With a different approach, the irradiation of a metal surface in calcium salts solution was used for the nucleation and growth of hydroxyapatite layers in a laser assisted biomimetic process. Recently, the possibility of modulating tribological, hydrophobic–hydrophilic or antibacterial properties of metallic or polymeric implants by surface structuring with high repetition ultra-short lasers has opened new prospectives to the use of laser sources in the preparation of biomedical materials.

The topics of interest of this Special Issue include, but are not limited to:

  • ns and fs PLD of thin films of bioactive glasses.
  • ns and fs PLD of thin films of ceramics for biological applications.
  • PLD of biogenic apatite.
  • Applications of laser texturing of metal implants.
  • Superhydrophobic–superhydrophilic surfaces by laser structuring.
  • Laser surface structuring of thermoplastics.
  • Selective laser sintering of composites and coatings.
  • Laser assisted techniques to improve tribological, mechanical and biomedical properties of biomedical materials.
  • Laser assisted biomimetic coating of metal implants
  • Laser ablation in liquid.

Prof. Dr. Roberto Teghil
Prof. Dr. Angela De Bonis
Dr. Mariangela Curcio
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Coatings is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • pulsed laser deposition
  • selective laser melting
  • laser assisted biomimetic process
  • laser assisted micro-nano structuring of surfaces
  • laser ablation in liquid

Published Papers (3 papers)

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Research

13 pages, 3623 KiB  
Article
Double Substituted with Manganese and Strontium Tricalcium Phosphate Coatings on Zinc-Lithium Biodegradable Alloys for Biomedical Implant Applications
by Julietta V. Rau, Angela De Bonis, Roberto Teghil, Mariangela Curcio, Inna V. Fadeeva, Katia Barbaro, Massimo Di Menno Di Bucchianico, Marco Fosca and Yufeng Zheng
Coatings 2023, 13(1), 36; https://doi.org/10.3390/coatings13010036 - 25 Dec 2022
Cited by 2 | Viewed by 1533
Abstract
To address the clinical needs for biodegradable implant materials, in this work, zinc-lithium (Zn-Li) biodegradable alloy was coated with double-doped manganese and strontium resorbable tricalcium phosphate (Mn,Sr-TCP). The Pulsed Laser Deposition method was applied for coating preparation. For coating characterization, Fourier Transform Infrared [...] Read more.
To address the clinical needs for biodegradable implant materials, in this work, zinc-lithium (Zn-Li) biodegradable alloy was coated with double-doped manganese and strontium resorbable tricalcium phosphate (Mn,Sr-TCP). The Pulsed Laser Deposition method was applied for coating preparation. For coating characterization, Fourier Transform Infrared Spectroscopy, X-ray Diffraction, Scanning Electron Microscopy coupled with Energy Dispersive X-ray, and X-ray Photoelectron Spectroscopy were used. The microbiology experiments were performed, testing the inhibition of growth of Gram-positive (Staphylococcus aureus, Enterococcus faecalis) and Gram-negative (Salmonella typhimurium, Escherichia coli) bacteria strains and Candida albicans fungus. The obtained results evidenced about 10% of inhibition of all four bacteria strains by the Mn,Sr-TCP-coated Zn-Li samples, exerting the most pronounced effect on C. albicans fungus (about 50% of inhibition of growth). The prepared coatings can be useful for improving the degradation behavior and biological characteristics of Zn-Li alloys. Full article
(This article belongs to the Special Issue Advances in Laser-Assisted Techniques for Biomedical Applications)
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11 pages, 6128 KiB  
Article
Mn-Doped Glass–Ceramic Bioactive (Mn-BG) Thin Film to Selectively Enhance the Bioactivity of Electrospun Fibrous Polymeric Scaffolds
by Mariangela Curcio, Brigida Bochicchio, Antonietta Pepe, Antonio Laezza, Adriana De Stefanis, Julietta V. Rau, Roberto Teghil and Angela De Bonis
Coatings 2022, 12(10), 1427; https://doi.org/10.3390/coatings12101427 - 29 Sep 2022
Cited by 2 | Viewed by 1634
Abstract
In recent years, significant progress has been made in the development of new technologies to meet the demand for engineered interfaces with appropriate properties for osteochondral unit repair and regeneration. In this context, we combined two methodologies that have emerged as powerful approaches [...] Read more.
In recent years, significant progress has been made in the development of new technologies to meet the demand for engineered interfaces with appropriate properties for osteochondral unit repair and regeneration. In this context, we combined two methodologies that have emerged as powerful approaches for tissue engineering application: electrospinning to fabricate a nanofibrous polymeric scaffold and pulsed laser deposition to tune and control the composition and morphology of the scaffold surface. A multi-component scaffold composed of synthetic and natural polymers was proposed to combine the biocompatibility and suitable mechanical properties of poly(D,L-lactic acid) with the hydrophilicity and cellular affinity of gelatin. As part of a biomimetic strategy for the generation of bi-functional scaffolds, we coated the electrospun fibers with a thin film of a bioactive glass–ceramic material supplemented with manganese ions. The physico-chemical properties and composition of the bi-layered scaffold were investigated, and its bioactivity, in terms of induced mineralization, was tested by incubation in a simulated body fluid buffer. The processes of the inorganic film dissolution and the calcium phosphate phases growth were followed by microscopic and spectroscopic techniques, confirming that a combination of bioactive glass–ceramics and nanofibrous scaffolds has promising potential in the regeneration of osteochondral tissue due to its ability to induce mineralization in connective tissues. Full article
(This article belongs to the Special Issue Advances in Laser-Assisted Techniques for Biomedical Applications)
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24 pages, 3819 KiB  
Article
Characterization of KrF Excimer Laser Ablation of Cadmium in Different Liquids for Biomedical and Industrial Applications
by Umm-i-Kalsoom, Nisar Ali, Shazia Bashir, Ali Mohammad Alshehri and Narjis Begum
Coatings 2022, 12(8), 1193; https://doi.org/10.3390/coatings12081193 - 16 Aug 2022
Cited by 3 | Viewed by 1474
Abstract
Liquid-assisted laser ablation (LALA) has gained substantial attention as a method that can achieve desired chemical and physical properties. The fabrication of carbides (CdCO3), oxides (CdO), and hydro-oxides (Cd(OH)2) on Cd surfaces make them more useful in industrial and [...] Read more.
Liquid-assisted laser ablation (LALA) has gained substantial attention as a method that can achieve desired chemical and physical properties. The fabrication of carbides (CdCO3), oxides (CdO), and hydro-oxides (Cd(OH)2) on Cd surfaces make them more useful in industrial and biomedical applications due to the enhancement of their physical properties. For this purpose, LALA of Cadmium (Cd) is performed using a KrF Excimer laser (248 nm, 20 ns) at varying numbers of pulses from 500 to 2000 at constant fluence (3.6 Jcm−2) in deionized water (DI) and ethanol. A comparison of the ablation behavior of Cd in DI water and alcohol (ethanol) environments is discussed in the present work. The surface structuring and enhancement of mechanical properties are also discussed in correlation with the changes produced in its crystallinity due to the increase in the chemical reactivity of Cd in both ambient environments. The surface features, chemical composition, structural and compositional analysis, and mechanical properties of irradiated targets are evaluated using a Scanning Electron Microscope (SEM), X-ray Diffraction (XRD), Fast Fourier Transform Infrared spectroscopic (FTIR), Energy Dispersive X-ray Spectroscopy (EDS), and a Nano-hardness tester. Pores, cavities, hillocks, wave-like ridges, nanoparticles, flake-like structures, and periodic surface structures are distinguished features on the Cd surface after irradiation. However, the density and size of pores and cavities are higher in water, whereas ethanol is favorable for the growth of craters and ripples. These features are attributable to various thermal and chemical phenomena induced by laser heating at the solid–liquid interface. Ethanol-assisted ablation is more favorable for enhancing the hardness of Cd as compared to DI water-assisted ablation due to the presence of maximum compressive stresses and minimum crystallite size (C.S.) caused by the diffusion of carbon into the target surface. Full article
(This article belongs to the Special Issue Advances in Laser-Assisted Techniques for Biomedical Applications)
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