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Current Oncology publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Novel Biomarkers and Liver Cancer

edited by

Panagiotis Papoutsoglou

and

Cédric Coulouarn

submission deadline 10 Oct 2025 | 2 articles | Viewed by 4806 | Submission Open

Keywords: biomarker; hepatocellular carcinoma; cholangiocarcinoma; prognosis; therapy response

(This special issue belongs to the Section Gastrointestinal Oncology)

Evolution of Treatments of Prostate Cancer: From Biology to Current Advanced Technologies

edited by

Fernando Munoz

submission deadline 31 Oct 2025 | 9 articles | Viewed by 20844 | Submission Open

Keywords: prostate cancer; combination therapy; radiation therapy; intensity-modulated radiotherapy; stereotactic radiotherapy; clinical advances; biological evolutions

(This special issue belongs to the Section Genitourinary Oncology)

Sarcoma Surgeries: Oncological Outcomes and Prognostic Factors

edited by Mai-Kim Gervais

submission deadline 31 Oct 2025 | 4 articles | Viewed by 3259 | Submission Open

Keywords: sarcoma; surgery; resection; prognostic factors; survival

(This special issue belongs to the Section Surgical Oncology)

The Evolving Role of Surgery in Multidisciplinary Care for Sarcoma Patients

edited by Russell G. Witt, Elizabeth Lilley and Heather Lyu

submission deadline 31 Oct 2025 | 3 articles | Viewed by 2805 | Submission Open

Keywords: soft tissue sarcoma; sarcoma; surgery; multidisciplinary approach; neoadjuvant therapy; adjuvant therapy; limb-sparing; histologic subtypes; oncologic outcomes

(This special issue belongs to the Section Bone and Soft Tissue Oncology)

Exploring Rare Gynecologic Tumors: A Cutting-Edge Perspective on Modern Diagnostic and Therapeutic Strategies

edited by

Brigida Anna Maiorano

and

Vera Loizzi

submission deadline 31 Oct 2025 | 1 articles | Viewed by 1256 | Submission Open

Keywords: vulvar cancer; rare gynecological tumor; Paget disease; uterine sarcoma; vaginal cancer; ovarian cancer; rare gynecological cancer; small cell carcinoma genital tract

(This special issue belongs to the Section Gynecologic Oncology)

Molecular Integrative Genomics in Cancer

edited by

Muhammad Kibriya

submission deadline 31 Oct 2025 | Viewed by 386 | Submission Open

Keywords: somatic mutation; cytogenetic abnormality; amplification; deletion; gene fusion; MSI; methylation; liquid biopsy; cell-free DNA; gene– environment interaction; targeted therapy; precision medicine

Advances in Melanoma: From Pathogenesis to Personalized Therapy

edited by

Patricia Tai

submission deadline 14 Nov 2025 | 1 articles | Viewed by 779 | Submission Open

Keywords: melanoma; clinical management; targeted therapy; immunotherapy; BRAF inhibitors; PD-1 blockade; predictive biomarkers; treatment resistance; combination therapy; liquid biopsy

(This special issue belongs to the Section Dermato-Oncology)

Combined Therapies for Hepatocellular Carcinoma

edited by

Hooman Yarmohammadi

submission deadline 15 Nov 2025 | 3 articles | Viewed by 4757 | Submission Open

Keywords: hepatocellular carcinoma; combined therapies; immunotherapy; locoregional therapy; external beam radiation

(This special issue belongs to the Section Gastrointestinal Oncology)

Feature Reviews in Section "Oncology Nursing"

edited by

Margaret Fitch

, Carmen Loiselle and

Doris Howell

submission deadline 30 Nov 2025 | 20 articles | Viewed by 36003 | Submission Open

Keywords: cancer care; survivor; oncology nursing

(This special issue belongs to the Section Oncology Nursing)

Hype or Hope—Combination Therapies for Lung Cancer

edited by Daniel Breadner

submission deadline 30 Nov 2025 | 5 articles | Viewed by 13968 | Submission Open

Keywords: NSCLC; chemo-immunotherapy; immunotherapy; chemoradiation; SCLC; combination therapies; duo-immunotherapy; targeted therapy

(This special issue belongs to the Section Thoracic Oncology)

Innovative Therapeutic Strategies, Biomarkers, and Molecular Pathways in Gastrointestinal and Hepatobiliary Cancers

edited by Anwaar Saeed and

Azhar Saeed

submission deadline 30 Nov 2025 | 3 articles | Viewed by 3913 | Submission Open

Keywords: gastrointestinal cancers; hepatobiliary cancers; immunotherapy; targeted therapies; combination treatments; biomarkers; early diagnosis; prognosis; personalized medicine; molecular pathways; drug development targets

(This special issue belongs to the Section Gastrointestinal Oncology)

Resistance to Chemotherapy and Targeted Therapy in Cancer: Understanding the Pathogenesis and Identifying the Best Approaches to Overcome This Challenge

edited by Oudai Hassan

submission deadline 30 Nov 2025 | 2 articles | Viewed by 1919 | Submission Open

Keywords: chemotherapy; targeted therapy; resistance; microenvironment; immunotherapy

Therapeutic Studies from Pre-Clinical to Clinical (Phase I–IV) for Gastrointestinal Cancers

edited by Erica S. Tsang

submission deadline 30 Nov 2025 | 1 articles | Viewed by 1162 | Submission Open

Keywords: gastrointestinal cancers; novel treatments; targeted therapies; immunotherapies; vaccine therapies

(This special issue belongs to the Section Gastrointestinal Oncology)

Advancements in Thyroid Cancer Management

edited by

Leonardo Rossi

submission deadline 30 Nov 2025 | 1 articles | Viewed by 1121 | Submission Open

Keywords: thyroid cancer; active surveillance; targeted therapy; lymph node dissection; thyroid nodule ablation; remote-access thyroidectomy; minimally invasive thyroidectomy; medullary thyroid carcinoma; anaplastic thyroid carcinoma

(This special issue belongs to the Section Head and Neck Oncology)

Therapeutic Advances in Cystectomy for Bladder Cancer

edited by Saum B. Ghodoussipour

submission deadline 30 Nov 2025 | Viewed by 201 | Submission Open

Keywords: bladder cancer; cystectomy; therapeutic advances; surgical techniques; personalized treatment

(This special issue belongs to the Section Genitourinary Oncology)

Advancing Precision Medicine in Hepatocellular Carcinoma: The Role of Circulating Tumor Cells

edited by

Amy K. Kim

submission deadline 30 Nov 2025 | Viewed by 169 | Submission Open

Keywords: circulating tumor cells; hepatocellular carcinoma; precision medicine; tumor heterogeneity; early diagnosis; prognosis; personalized treatment

(This special issue belongs to the Section Cell Therapy)

Social Determinants of Health and Breast Cancer: Impacts on Diagnosis, Treatment, and Outcomes

edited by Charlotte Yong-Hing and Nathalie LeVasseur

submission deadline 15 Dec 2025 | 3 articles | Viewed by 5514 | Submission Open

Keywords: social determinants of health; breast cancer disparities; healthcare access; health equity; screening and diagnosis; treatment outcomes; socioeconomic factors; racial and ethnic disparities; healthcare policy; marginalized populations

(This special issue belongs to the Section Breast Cancer)

Advances in B-Cell Lymphoma: From Diagnostics to Cure

edited by

Leo I. Gordon

and Megan E. Melody

submission deadline 15 Dec 2025 | 2 articles | Viewed by 4174 | Submission Open

Keywords: B-cell lymphoma; treatment; molecular profiling; immunotherapies; cellular therapies

Recent Advances in Surgical Strategies for Managing Metastatic Colorectal Cancer

edited by Fabrizio D'Acapito and Marco Vaira

submission deadline 15 Dec 2025 | 2 articles | Viewed by 3111 | Submission Open

Keywords: metastatic colorectal cancer; liver metastases; parenchymal-sparing hepatectomy; staged hepatectomy; minimally invasive liver resection; cytoreductive surgery; HIPEC; PIPAC; peritoneal surface metastases; biomarker-based stratification

(This special issue belongs to the Section Gastrointestinal Oncology)

The Impact of Tumor Microenvironment on Therapeutic Resistance

edited by

Ziqing Chen

submission deadline 15 Dec 2025 | Viewed by 259 | Submission Open

Keywords: tumor microenvironment; therapeutic resistance; stromal– immune crosstalk

Advances in Radiation Treatment for Brain Tumors

edited by Andra Krauze

submission deadline 15 Dec 2025 | Viewed by 211 | Submission Open

Keywords: personalized treatment; artificial intelligence; automation; segmentation; adaptive treatment; immune modulation; fed-erated learning; multi-omics

(This special issue belongs to the Section Neuro-Oncology)

Novel Therapies for B-Cell Lymphomas

edited by David MacDonald

submission deadline 15 Dec 2025 | Viewed by 142 | Submission Open

Keywords: B-cell lymphomas; non-Hodgkin lymphomas; targeted therapy; CAR-T cell therapy; bispecific antibodies; biomarker-driven treatment; translational research; clinical trials

(This special issue belongs to the Section Hematology)

Pathways to Recovery and Resilience in Breast Cancer Survivorship

edited by Nazanin Derakhshan

submission deadline 31 Dec 2025 | 4 articles | Viewed by 12511 | Submission Open

Keywords: breast cancer; intervention; mixed methods; digital health; personalized care; AI; resilience; anxiety; depression; neuroscience

(This special issue belongs to the Section Psychosocial Oncology)

New and Emerging Trends in Prostate Cancer

edited by

Tamim Niazi

and Steven Tisseverasinghe

submission deadline 31 Dec 2025 | 7 articles | Viewed by 10651 | Submission Open

Keywords: prostate SBRT; recurrent prostate cancer; treatment intensification with ARPIs; PARP inhibitors; lutetium-177; immunotherapy; oligometastases

(This special issue belongs to the Section Genitourinary Oncology)

Optimizing Surgical Management for Gynecologic Cancers

edited by Jacob D. McGee

submission deadline 31 Dec 2025 | 3 articles | Viewed by 5163 | Submission Open

Keywords: pre-operative optimization; de-escalation; surgical approach; risk stratification; quality of Life; novel techniques

(This special issue belongs to the Section Gynecologic Oncology)

Advanced Research on Breast Cancer Genes in Cancers

edited by Andrea Eisen

submission deadline 31 Dec 2025 | 3 articles | Viewed by 4414 | Submission Open

Keywords: breast cancer genes; BRCA1/2 mutations; cancer genomics; targeted therapies; precision medicine; genetic counseling

(This special issue belongs to the Section Oncology Biomarkers)

2nd Edition—Haematological Neoplasms: Diagnosis and Management

edited by

Stefano Ascani

Magda Zanelli

and

Francesca Sanguedolce

submission deadline 31 Dec 2025 | 2 articles | Viewed by 3211 | Submission Open

Keywords: myeloid neoplasms; lymphoid neoplasms; pathology; molecular biology; precision medicine; biomarkers

(This special issue belongs to the Section Hematology)

Recent Advances in Immune Checkpoint Inhibition and Antibody Drug Conjugates in Urothelial Carcinoma

edited by Qian Janie Qin

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1664 | Submission Open

Keywords: immune checkpoint inhibition; antibody drug conjugates; urothelial carcinoma; therapeutic combinations; biomarkers; resistance mechanisms; treatment efficacy; cancer immunotherapy

(This special issue belongs to the Section Genitourinary Oncology)

Clinical Advances in Thyroid Cancer: Biomarker-Driven Diagnosis, Oncogenesis Insights, and Translational Therapies

edited by Salma Khan

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1085 | Submission Open

Keywords: thyroid cancer; oncogenesis; translational therapies; fine-needle aspiration (FNA); precision medicine; targeted therapy

(This special issue belongs to the Section Head and Neck Oncology)

Combining Radiotherapy and Immunotherapy for Cancer Treatment

edited by Yufei Liu

submission deadline 31 Dec 2025 | Viewed by 356 | Submission Open

Keywords: radiation oncology; immunotherapy; immunomodulation; immune checkpoint inhibitors; abscopal effect; stereotactic body ra-diation therapy; antibody– drug conjugate; CAR-T cell therapy; tumor-infiltrating lymphocytes

Psychological Interventions for Cancer Survivors

edited by Christian Schulz-Quach

submission deadline 31 Dec 2025 | Viewed by 269 | Submission Open

Keywords: cancer survivors; psychological interventions; mental health; quality of life; existential– phenomenological approaches; relational frameworks; resilience; evidence-based therapies; post-treatment care

(This special issue belongs to the Section Psychosocial Oncology)

2nd Edition—Chronic Lymphocytic Leukemia: Therapy and Outcome

edited by

Andrea Visentin

submission deadline 31 Dec 2025 | Viewed by 181 | Submission Open

Keywords: chronic lymphocytic leukemia; microenvironment; BTK inhibitors; BCL2 inhibitors; PI3K inhibitors; infection; prognostic factors; predictive factors; richter syndrome

(This special issue belongs to the Section Hematology)

REAL Canadian Breast Cancer Alliance Collection

edited by Katarzyna J. Jerzak, Nathalie LeVasseur,

Nathaniel Bouganim

and

Mita Manna

submission deadline 31 Dec 2025 | Viewed by 19 | Submission Open

Keywords: HER2-positive; hormone receptor-positive; triple-negative; metastatic breast cancer; early-stage breast cancer; Canadian consensus recommendations; evidence-based; REAL Alliance

(This special issue belongs to the Section Breast Cancer)

Clinical Progression and Treatment Outcome of Multiple Myeloma

edited by Guido Lancman, Alissa Visram and Rayan Kaedbey

submission deadline 15 Jan 2026 | 2 articles | Viewed by 4214 | Submission Open

Keywords: multiple myeloma; real-world predictors of response; sequencing; treatment selection; resistance mechanisms

(This special issue belongs to the Section Hematology)

Estrogen-Receptor Low Positive (ER-Low) Breast Cancer: A New (or Old?) World to Discover

edited by Eleonora Lai and

Gavino Faa

submission deadline 15 Jan 2026 | Viewed by 416 | Submission Open

Keywords: breast cancer; estrogen receptor low positive; treatment implications; endocrine treatment; immunotherapy; chemotherapy; translational research; clinical research

(This special issue belongs to the Section Breast Cancer)

Surgical Advances in the Management of Gastrointestinal Cancers

edited by Boris Luis Gala-López

submission deadline 15 Jan 2026 | Viewed by 197 | Submission Open

Keywords: gastrointestinal cancers; surgical innovation; multimodal therapy; precision oncology; minimally invasive surgery

(This special issue belongs to the Section Gastrointestinal Oncology)

Self-Management/Patient Activation and Self-Management Support Interventions for Cancer Survivors

edited by

Doris Howell

submission deadline 31 Jan 2026 | 3 articles | Viewed by 5019 | Submission Open

Keywords: self-management interventions; supported self-management; health coaching; patient activation; healthy lifestyle behaviors; patient activation; cancer and cancer survivorship

(This special issue belongs to the Section Oncology Nursing)

Routine Screening for Distress, Depression and Anxiety in Oncology: Where Are We Now?

edited by Daniel C. McFarland and Lee A. Kehoe

submission deadline 31 Jan 2026 | 1 articles | Viewed by 737 | Submission Open

Keywords: psychological distress; depression; anxiety; oncology; routine screening; cancer care; patient outcomes

(This special issue belongs to the Section Psychosocial Oncology)

Advances in Multiparametric MRI and Artificial Intelligence for Bladder Cancer: From Diagnosis to Personalized Treatment Strategies

edited by

Thierry Boellaard

submission deadline 31 Jan 2026 | Viewed by 209 | Submission Open

Keywords: multiparametric MRI; artificial intelligence; bladder cancer; diagnosis; personalized treatment strategies; prognosis

(This special issue belongs to the Section Genitourinary Oncology)

Basal Cell Carcinoma: Diagnosis, Treatment and Prognosis

edited by Andrzej Bieniek

submission deadline 31 Jan 2026 | Viewed by 165 | Submission Open

Keywords: basal cell carcinoma; skin cancer; diagnostic techniques; surgical and non-surgical treatment modalities; targeted therapies; long-term management and prevention

(This special issue belongs to the Section Dermato-Oncology)

Patient-Reported Outcomes Including Health-Related Quality of Life in Cancer Clinical Trials

edited by Caroline Hamm

submission deadline 31 Jan 2026 | Viewed by 157 | Submission Open

Keywords: patient-reported outcomes; guidelines; health-related quality of life; clinical trials; ethical considerations; prognosis

(This special issue belongs to the Section Palliative and Supportive Care)

Cancer Rehabilitation: Innovations in Practice & Enhancing Survivorship Care

edited by

David M. Langelier

and Sara Parke

submission deadline 15 Feb 2026 | 1 articles | Viewed by 731 | Submission Open

Keywords: cancer rehabilitation; physiatry; survivorship; symptom management; impairment; disability

(This special issue belongs to the Section Palliative and Supportive Care)

Adaptive Radiotherapy: Advanced Imaging for Personalised Treatment

edited by

Sweet Ping Ng

and Michael G. Jameson

submission deadline 15 Feb 2026 | Viewed by 147 | Submission Open

Keywords: adaptive radiotherapy; advanced imaging; personalized radiotherapy

Clinical Outcomes and New Treatments in Pediatric Brain Tumors

edited by Sébastien Perreault and Craig Erker

submission deadline 28 Feb 2026 | 6 articles | Viewed by 12240 | Submission Open

Keywords: pediatric neuro-oncology; central nervous system tumors; treatment approaches

(This special issue belongs to the Section Neuro-Oncology)

Bridging Borders: A Global Perspective on Colorectal Cancer Research and Prevention

edited by

Laith Alrubaiy

submission deadline 28 Feb 2026 | 1 articles | Viewed by 2746 | Submission Open

Keywords: colorectal cancer (CRC); global health; mass screening; early detection of cancer; artificial intelligence (AI); epidemiology; health disparities; diagnostic technologies; public health; therapeutics

(This special issue belongs to the Section Gastrointestinal Oncology)

Immunotherapy for Head and Neck Cancer: Biomarkers, Trials, and Transformative Outcomes

edited by

Jong Chul Park

submission deadline 28 Feb 2026 | Viewed by 90 | Submission Open

Keywords: immunotherapy; head and neck cancer; biomarkers; combination therapy; clinical outcomes

(This special issue belongs to the Section Head and Neck Oncology)

Innovations in the Clinical Research of Chronic Myeloid Leukemia: From Targeted Therapies to Allogeneic Stem Cell Transplantation

edited by Jeffrey H. Lipton

submission deadline 28 Feb 2026 | Viewed by 82 | Submission Open

Keywords: chronic myeloid leukemia; tyrosine kinase inhibitors; treatment resistance; allogeneic stem cell transplantation; stem cell persistence; treatment-free remission; targeted therapies

(This special issue belongs to the Section Hematology)

Future Perspectives for Treatment and Diagnosis of Acute Myeloid Leukemia (AML)

edited by

Mitchell Sabloff

and Brian Leber

submission deadline 1 Mar 2026 | 2 articles | Viewed by 3354 | Submission Open

Keywords: pathophysiology; biomarker; diagnosis/prognosis/predictive/monitoring (indication/limitations); treatment advances; intensive; less intensive; refractory leukemia; cellular therapies

(This special issue belongs to the Section Hematology)

Biliary Tract Cancer Updates: Advancements and Insights

edited by Kristen R. Spencer

submission deadline 15 Mar 2026 | 8 articles | Viewed by 14532 | Submission Open

Keywords: biliary tract cancer; intrahepatic cholangiocarcinoma; extrahepatic cholangiocarcinoma; gallbladder cancer; targeted therapy; immunotherapy; molecular profiling; clinical trials

(This special issue belongs to the Section Gastrointestinal Oncology)

Cost Effectiveness vs. Affordability in the Age of Targeted Drug Therapies

edited by Ramy Saleh

submission deadline 15 Mar 2026 | 4 articles | Viewed by 6649 | Submission Open

Keywords: cost-effectiveness; affordability; drugs; financial; cancers; treatment; targeted drug therapies

(This special issue belongs to the Section Health Economics)

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