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Current Oncology publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Hope Amidst Challenges: Therapies for Relapsed/Refractory Multiple Myeloma

edited by

Martha L. Louzada

submission deadline 10 Aug 2026 | Viewed by 335 | Submission Open

Keywords: RRMM; quadruplet therapy; CART-cell; bispecific antibodies; antibody drug conjugates (ADC); minimal residual disease (MRD)

(This special issue belongs to the Section Hematology)

Surgical Advances in the Management of Gastrointestinal Cancers

edited by Boris Luis Gala-López

submission deadline 15 Aug 2026 | 3 articles | Viewed by 4273 | Submission Open

Keywords: gastrointestinal cancers; surgical innovation; multimodal therapy; precision oncology; minimally invasive surgery

(This special issue belongs to the Section Gastrointestinal Oncology)

Glioblastoma: Symptoms, Causes, Treatment and Prognosis

edited by Giuseppe Lombardi and Alberto Bosio

submission deadline 30 Aug 2026 | 3 articles | Viewed by 3427 | Submission Open

Keywords: glioblastoma; molecular biomarkers; targeted therapy; immunotherapy; imaging; tumor microenvironment; prognosis

(This special issue belongs to the Section Neuro-Oncology)

The Evolving Landscape of Precision Medicine in Radiation Oncology

edited by

Fernando Munoz

submission deadline 31 Aug 2026 | 2 articles | Viewed by 7529 | Submission Open

Keywords: biomarkers; genomics; precision medicine; transcriptomics; radiotherapy response prediction

Advances in Endocrine Therapy for Breast Cancer

edited by

Sandeep Sehdev

, Arif Ali Awan and

Karen A. Gelmon

submission deadline 31 Aug 2026 | 3 articles | Viewed by 2801 | Submission Open

Keywords: endocrine therapy; breast cancer; endocrine resistance; CDK 4/6 inhibitor; biomarkers; selective endocrine receptor degraders (SERDs)

(This special issue belongs to the Section Breast Cancer)

Patient-Reported Outcomes Including Health-Related Quality of Life in Cancer Clinical Trials

edited by Caroline Hamm

submission deadline 31 Aug 2026 | 2 articles | Viewed by 2342 | Submission Open

Keywords: patient-reported outcomes; guidelines; health-related quality of life; clinical trials; ethical considerations; prognosis

(This special issue belongs to the Section Palliative and Supportive Care)

Radiation Therapy and Targeted Therapies for Pancreatic Cancer

edited by Aswin Abraham

submission deadline 31 Aug 2026 | 1 articles | Viewed by 1194 | Submission Open

Keywords: pancreatic cancer; radiation; chemo-radiation; SBRT; patterns of failure; radiobiology; radiation techniques; cell signaling; immunotherapy and radiation; targeted therapies

(This special issue belongs to the Section Gastrointestinal Oncology)

Advances in Implementation Science and Knowledge Mobilization for Cancer Control

edited by

Sarah Neil-Sztramko

submission deadline 31 Aug 2026 | Viewed by 721 | Submission Open

Keywords: evidence-based interventions; cancer control; cancer prevention; cancer treatment; survivorship; knowledge mobilization; implementation science

Treatment of High-Grade Glioma

edited by Chiara Valentini and Silvia Chiesa

submission deadline 31 Aug 2026 | Viewed by 426 | Submission Open

Keywords: high-grade glioma; treatment; surgery; radiation therapy; chemotherapy; targeted therapy; immunotherapy

(This special issue belongs to the Section Neuro-Oncology)

Role of Inflammation in Cancer

edited by

Li Yang

submission deadline 31 Aug 2026 | Viewed by 423 | Submission Open

Keywords: cancer; inflammation; immune cells; cytokines; anti-inflammatory; tumor microenvironment; immunotherapy; immune-related adverse events; targeted therapy; chemotherapy and chemoprevention

Glioblastoma: The Emerging Challenges in Rapidly Evolving Social Changes

edited by Andrea Talacchi and Andrea Pace

submission deadline 31 Aug 2026 | Viewed by 340 | Submission Open

Keywords: glioblastoma; glioma; social determinants; prognostic factors; clinical pathways; lifestyle; economic determinants; frailty; area deprivation; brain neoplasm; overall survival

(This special issue belongs to the Section Neuro-Oncology)

Emphasis on Cardiovascular Health from Cancer Therapy: Incidence, Mechanisms, and Management

edited by Brijesh D. Patel

submission deadline 10 Sep 2026 | 1 articles | Viewed by 1465 | Submission Open

Keywords: cardiotoxicity; cancer therapy-related cardiac dysfunction (CTRCD); arrhythmia; cardiomyopathy; disparity; innovation; prevention

2nd Edition: Stereotactic Radiosurgery for Brain Tumors

edited by Dante Amelio,

Piera Navarria

and Giuseppe Minniti

submission deadline 15 Sep 2026 | 1 articles | Viewed by 1247 | Submission Open

Keywords: stereotactic radiosurgery; gamma knife; cyber knife; particle therapy; brain tumors; skull base tumors

Health-Related Quality of Life of Pediatric Cancer Survivors

edited by

John T. Lucas, Jr.

and

I-Chan Huang

submission deadline 15 Sep 2026 | Viewed by 458 | Submission Open

Keywords: pediatric oncology; cancer survivorship; health-related quality of life (HRQoL); patient-reported outcomes (PROs); late effects of treatment; psychosocial oncology; neurocognitive functioning; long-term follow-up care

(This special issue belongs to the Section Childhood, Adolescent and Young Adult Oncology)

Pathways to Recovery and Resilience in Breast Cancer Survivorship

edited by Nazanin Derakhshan

submission deadline 30 Sep 2026 | 5 articles | Viewed by 25590 | Submission Open

Keywords: breast cancer; intervention; mixed methods; digital health; personalized care; AI; resilience; anxiety; depression; neuroscience

(This special issue belongs to the Section Psychosocial Oncology)

Palliative Care in Oncology: Current Advances

edited by Olav F. Dajani,

Arne Westgaard

and Martin Kummen

submission deadline 30 Sep 2026 | 5 articles | Viewed by 5804 | Submission Open

Keywords: palliative care; oncology; cancers; pain; support; well-being

(This special issue belongs to the Section Palliative and Supportive Care)

Systemic Therapy in Hepatocellular Carcinoma: Current Challenges and Future Directions

edited by Andrea Martini and

Alessandro Vitale

submission deadline 30 Sep 2026 | 1 articles | Viewed by 2297 | Submission Open

Keywords: immunotherapy; conversion therapy; hepatocellular carcinoma; surgical therapy: transplantation

(This special issue belongs to the Section Gastrointestinal Oncology)

Evolving Role of Surgical Resection in Pancreatic Cancer

edited by Eran Sadot, Oran Zlotnik and

Nasser Abdul Halim

submission deadline 30 Sep 2026 | 1 articles | Viewed by 887 | Submission Open

Keywords: pancreatic cancer; surgical resection; pancreaticoduodenectomy; distal pancreatectomy; vascular resection; borderline resectable disease; neoadjuvant therapy; minimally invasive surgery; oncologic outcomes; prognostic factors

(This special issue belongs to the Section Surgical Oncology)

Treatment Strategies for Advanced Urothelial Carcinoma

edited by Manojkumar Bupathi

submission deadline 30 Sep 2026 | Viewed by 442 | Submission Open

Keywords: advanced urothelial carcinoma; metastatic bladder cancer; FGFR-targeted therapy; immune checkpoint inhibitors; PD-L1 expression; therapeutic sequencing; combination therapy; treatment resistance; clinical outcomes; personalized oncology

(This special issue belongs to the Section Genitourinary Oncology)

Oncovascular Surgery: Blood Vessel Reconstruction and Tumor Resection

edited by Pirkka J. Vikatmaa and

Federica Campana

submission deadline 30 Sep 2026 | Viewed by 409 | Submission Open

Keywords: oncovascular surgery; vascular reconstruction; tumor resection; inferior vena cava thrombus; portomesenteric re-construction; sarcoma surgery; multidisciplinary cancer surgery; arterial reconstruction; venous reconstruction; complex oncologic surgery

(This special issue belongs to the Section Surgical Oncology)

Liver Transplantation in Oncology: Perspectives on Medical and Surgical Aspects

edited by

Paul J. Gaglio

and Keri E. Lunsford

submission deadline 30 Sep 2026 | Viewed by 309 | Submission Open

Keywords: liver transplantation; hepatocellular carcinoma; cholangiocarcinoma; liver cancer surgery; loco-regional therapies; downstaging; adjunctive therapies; metastatic liver tumors; transplant eligibility; transplant outcomes

(This special issue belongs to the Section Surgical Oncology)

Supportive Care in Cancer

edited by

Jeffrey R. Hanna

and

Cherith J. Semple

submission deadline 30 Sep 2026 | Viewed by 101 | Submission Open

Keywords: supportive care; psychosocial; cancer; intersectionality; rehabilitation; communication; survivorship

(This special issue belongs to the Section Palliative and Supportive Care)

Future Perspectives for Treatment and Diagnosis of Acute Myeloid Leukemia (AML)

edited by

Mitchell Sabloff

and Brian Leber

submission deadline 31 Oct 2026 | 5 articles | Viewed by 11477 | Submission Open

Keywords: pathophysiology; biomarker; diagnosis/prognosis/predictive/monitoring (indication/limitations); treatment advances; intensive; less intensive; refractory leukemia; cellular therapies

(This special issue belongs to the Section Hematology)

AI-Powered Oncologic Nuclear Medicine in Clinical Translation: Advanced Assessment of Tumor Load and Microenvironment

edited by

Christian Furth

submission deadline 31 Oct 2026 | 3 articles | Viewed by 3108 | Submission Open

Keywords: AI in nuclear medicine; PET- and SPECT-imaging; radiomics and deep learning; tumor microenvironment; tumor burden quantification; theranostics; precision oncology; immuno-oncology imaging; clinical translation; predictive modeling

Innovations in Patient-Centred Palliative Radiotherapy in Oncology: From Clinical Trials to Real-World Practice

edited by Alysa Fairchild

submission deadline 31 Oct 2026 | 2 articles | Viewed by 2322 | Submission Open

Keywords: palliative radiotherapy; palliative radiation oncology program; interdisciplinary team; quality of life; patient-centred care; radiotherapy delivery model; patient-reported outcomes; palliative care

(This special issue belongs to the Section Palliative and Supportive Care)

Quality of Life in Surgical Oncology Patients

edited by Neil Merrett

submission deadline 31 Oct 2026 | 3 articles | Viewed by 1961 | Submission Open

Keywords: PROMS; quality of life; health economics; surgical oncology; precision medicine; robotic surgery

(This special issue belongs to the Section Surgical Oncology)

Genomic and Molecular Profiling in Genitourinary Oncology: Shaping the Future of Diagnosis and Treatment

edited by

Ricardo Fernandes

and Lilian Hanna

submission deadline 31 Oct 2026 | 1 articles | Viewed by 1377 | Submission Open

Keywords: genito-urinary malignancies; molecular profiling; genomics; biomarkers; targeted therapy; precision oncology; liquid biopsy; translational research

(This special issue belongs to the Section Genitourinary Oncology)

Advances in the Orthopaedic Oncology

edited by

Hisaki Aiba

submission deadline 31 Oct 2026 | 2 articles | Viewed by 1282 | Submission Open

Keywords: limb sparing surgery; personalized surgery; mechanisms of tumor progression; radiotherapy; chemotherapy; immunotherapy; targeted therapy

(This special issue belongs to the Section Bone and Soft Tissue Oncology)

Desmoid Tumor: Challenging and Conquerable Rare Disease

edited by Kelly Mercier and Alessandra Maleddu

submission deadline 31 Oct 2026 | Viewed by 524 | Submission Open

Keywords: desmoid tumors; aggressive fibromatosis; β-catenin; patient-reported outcomes; rare disease advocacy

(This special issue belongs to the Section Bone and Soft Tissue Oncology)

Modern Perspectives on Non-Melanoma Skin Cancer

edited by

Soo J. Park

submission deadline 31 Oct 2026 | Viewed by 400 | Submission Open

Keywords: non-melanoma skin cancers; merkel cell carcinoma; basal cell carcinoma; cutaneous squamous cell carcinoma; diagnosis; prognosis; therapeutic strategies

(This special issue belongs to the Section Dermato-Oncology)

Enhancing Sexual Health as a Core Component of Cancer Survivorship

edited by Trustin S. Domes

submission deadline 31 Oct 2026 | Viewed by 316 | Submission Open

Keywords: cancer survivorship; sexual health; sexual dysfunction; quality of life; biopsychosocial approach; psychosexual well-being; oncology care; cancer-related treatment effects; access to sexual health care

(This special issue belongs to the Section Psychosocial Oncology)

Behavioural Interventions and Patient-Centred Approaches in Skin Cancer

edited by

Ivan V. Litvinov

and

Sandra Peláez

submission deadline 31 Oct 2026 | Viewed by 278 | Submission Open

Keywords: patient-centred care; behavioural interventions; patient perspectives and emotions; self-management and treatment adherence; public health strategies

(This special issue belongs to the Section Dermato-Oncology)

Sentinel Lymph Node Mapping in Breast Cancer: Applications and Outcomes

edited by Yasuyuki Kojima and Yasue Tsuchida

submission deadline 31 Oct 2026 | Viewed by 269 | Submission Open

Keywords: sentinel lymph node biopsy; axillary management; magnetic tracer; neoadjuvant chemotherapy; axillary reverse mapping (ARM); targeted axillary dissection (TAD); lymphedema prevention; lymphatic mapping; de-escalation surgery; minimal invasive surgery

(This special issue belongs to the Section Surgical Oncology)

Personalized Medicine and Multidisciplinary Approaches to Thoracic Malignancies

edited by Sara Kuruvilla

submission deadline 10 Nov 2026 | 1 articles | Viewed by 1160 | Submission Open

Keywords: personalized medicine; precision oncology; thoracic malignancies; lung cancer; multidisciplinary team; targeted therapy; immunotherapy; biomarkers; artificial intelligence; treatment resistance

(This special issue belongs to the Section Thoracic Oncology)

Clinical Advances and Therapeutic Challenges in Small-Cell Lung Cancer and Rare Thoracic Cancers

edited by

Tommaso Martino De Pas

submission deadline 15 Nov 2026 | 4 articles | Viewed by 10031 | Submission Open

Keywords: pleural mesothelioma; thymic cancer; neuroendocrine thoracic tumors; small-cell lung cancer; rare tumors; thoracic cancer

(This special issue belongs to the Section Thoracic Oncology)

Cancer Rehabilitation: Innovations in Practice & Enhancing Survivorship Care

edited by

David M. Langelier

and Sara Parke

submission deadline 15 Nov 2026 | 6 articles | Viewed by 9683 | Submission Open

Keywords: cancer rehabilitation; physiatry; survivorship; symptom management; impairment; disability

(This special issue belongs to the Section Palliative and Supportive Care)

Clinical Progression and Treatment Outcome of Multiple Myeloma

edited by Guido Lancman, Alissa Visram and Rayan Kaedbey

submission deadline 15 Nov 2026 | 2 articles | Viewed by 6940 | Submission Open

Keywords: multiple myeloma; real-world predictors of response; sequencing; treatment selection; resistance mechanisms

(This special issue belongs to the Section Hematology)

Advances in Surgical Treatment of Children with Bone Tumors

edited by

Costantino Errani

and

Shinji Tsukamoto

submission deadline 15 Nov 2026 | Viewed by 656 | Submission Open

Keywords: bone tumors; children; limb salvage surgery; massive bone allograft; prosthetic reconstruction; vascu-larized fibula; massive bone autograft

(This special issue belongs to the Section Bone and Soft Tissue Oncology)

Advances in Thoracic Oncology: From Surgical Innovation to Outcome Optimization

edited by Silvia Novello and

Francesco Leo

submission deadline 30 Nov 2026 | 3 articles | Viewed by 3504 | Submission Open

Keywords: lung cancer; multimodality treatment; thoracic surgery; target therapy; immunotherapy

(This special issue belongs to the Section Thoracic Oncology)

Immunotherapy for Melanoma: Systemic and Locoregional Approaches, Mechanisms, and Future Directions

edited by Russell G. Witt and Sarah Bateni

submission deadline 30 Nov 2026 | 3 articles | Viewed by 2982 | Submission Open

Keywords: melanoma; immunotherapy; checkpoint blockade; tumor microenvironment; resistance; biomarkers; intratumoral therapy; adoptive cell therapy; cancer vaccines

(This special issue belongs to the Section Dermato-Oncology)

Innovation in Gynecologic Cancer Surgery

edited by

Sarfraz Ahmad

submission deadline 30 Nov 2026 | 3 articles | Viewed by 2381 | Submission Open

Keywords: hysterectomy; gynecologic cancers; surgical oncology; minimally invasive surgery; fertility preservation; survivorship; cost-effectiveness

(This special issue belongs to the Section Gynecologic Oncology)

Artificial Intelligence Applications in Stereotactic Radiosurgery and Neurosurgical Oncology

edited by

Maleeha Ahmad

and Susan C. Pannullo

submission deadline 30 Nov 2026 | Viewed by 356 | Submission Open

Keywords: stereotactic radiosurgery; cranial neurosurgical oncology; artificial intelligence; machine learning; radiomics and radiogenomics; precision medicine; predictive modeling and outcome prediction; treatment planning and workflow optimization; translational neurosurgery; clinical integration and implementation science

(This special issue belongs to the Section Neuro-Oncology)

Oncofertility and Therapeutic Modalities

edited by

Luke D. E. Witherspoon

submission deadline 30 Nov 2026 | Viewed by 305 | Submission Open

Keywords: oncofertility; fertility preservation; cancer survivorship; reproductive health; gonadotoxicity; hormonal dysfunction; pediatric and adolescent oncology; reproductive endocrinology

Sleep Disturbance and Fatigue During Cancer: Incidence, Impact, Intervention, and Innovation

edited by

Hannah Fisher

and Alexandria Muench

submission deadline 30 Nov 2026 | Viewed by 231 | Submission Open

Keywords: sleep disturbance; cancer trajectory; cancer-related fatigue; assessment methodologies; cancer outcomes; circadian and homeostatic regulation; behavioral intervention; care delivery innovation

(This special issue belongs to the Section Psychosocial Oncology)

Neoadjuvant Endocrine Therapy in Breast Cancer

edited by Covadonga Martí

submission deadline 30 Nov 2026 | Viewed by 198 | Submission Open

Keywords: breast cancer; neoadjuvant endocrine therapy; hormone receptor–positive; aromatase inhibitors; ki67; breast-conserving surgery; endocrine responsiveness

(This special issue belongs to the Section Breast Cancer)

Advanced Research on Breast Cancer Genes in Cancers

edited by Andrea Eisen

submission deadline 31 Dec 2026 | 8 articles | Viewed by 17649 | Submission Open

Keywords: breast cancer genes; BRCA1/2 mutations; cancer genomics; targeted therapies; precision medicine; genetic counseling

(This special issue belongs to the Section Oncology Biomarkers)

Advances in Geriatric Oncology: Toward Optimized Cancer Care

edited by Michael J. Lind

submission deadline 31 Dec 2026 | 8 articles | Viewed by 15030 | Submission Open

Keywords: oncogeriatrics; clinical trials; prehabilitation; elderly cancer patients; cancer care

(This special issue belongs to the Section Palliative and Supportive Care)

U.S. Myeloma Innovations Research Collaborative (USMIRC) Collection

edited by Al-Ola A. Abdallah

submission deadline 31 Dec 2026 | 6 articles | Viewed by 13609 | Submission Open

Keywords: multiple myeloma; immunotherapy; cellular therapy; CAR-T; T-cell engagers; TCE; multispecifics; BCMA; GPRC5D; plasmacytoma

(This special issue belongs to the Section Hematology)

REAL Canadian Breast Cancer Alliance Collection

edited by Katarzyna J. Jerzak, Nathalie LeVasseur,

Nathaniel Bouganim

and

Mita Manna

submission deadline 31 Dec 2026 | 4 articles | Viewed by 11830 | Submission Open

Keywords: HER2-positive; hormone receptor-positive; triple-negative; metastatic breast cancer; early-stage breast cancer; Canadian consensus recommendations; evidence-based; REAL Alliance

(This special issue belongs to the Section Breast Cancer)

Microsurgical Management of Chronic Cancer-Related Lymphedema

edited by Elisabeth A. Kappos and

Adriano Fabi

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1573 | Submission Open

Keywords: microsurgery; chronic cancer-related lymphedema; lymphatic reconstruction; surgical techniques; quality of life

(This special issue belongs to the Section Surgical Oncology)

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