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Current Oncology publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Cancer Rehabilitation: Innovations in Practice & Enhancing Survivorship Care

edited by

David M. Langelier

and Sara Parke

submission deadline 15 Feb 2026 | 4 articles | Viewed by 4722 | Submission Open

Keywords: cancer rehabilitation; physiatry; survivorship; symptom management; impairment; disability

(This special issue belongs to the Section Palliative and Supportive Care)

Adaptive Radiotherapy: Advanced Imaging for Personalised Treatment

edited by

Sweet Ping Ng

and Michael G. Jameson

submission deadline 15 Feb 2026 | 1 articles | Viewed by 956 | Submission Open

Keywords: adaptive radiotherapy; advanced imaging; personalized radiotherapy

Clinical Outcomes and New Treatments in Pediatric Brain Tumors

edited by Sébastien Perreault and Craig Erker

submission deadline 28 Feb 2026 | 7 articles | Viewed by 22867 | Submission Open

Keywords: pediatric neuro-oncology; central nervous system tumors; treatment approaches

(This special issue belongs to the Section Neuro-Oncology)

Bridging Borders: A Global Perspective on Colorectal Cancer Research and Prevention

edited by

Laith Alrubaiy

submission deadline 28 Feb 2026 | 1 articles | Viewed by 4896 | Submission Open

Keywords: colorectal cancer (CRC); global health; mass screening; early detection of cancer; artificial intelligence (AI); epidemiology; health disparities; diagnostic technologies; public health; therapeutics

(This special issue belongs to the Section Gastrointestinal Oncology)

Immunotherapy for Head and Neck Cancer: Biomarkers, Trials, and Transformative Outcomes

edited by

Jong Chul Park

submission deadline 28 Feb 2026 | Viewed by 271 | Submission Open

Keywords: immunotherapy; head and neck cancer; biomarkers; combination therapy; clinical outcomes

(This special issue belongs to the Section Head and Neck Oncology)

Future Perspectives for Treatment and Diagnosis of Acute Myeloid Leukemia (AML)

edited by

Mitchell Sabloff

and Brian Leber

submission deadline 1 Mar 2026 | 2 articles | Viewed by 6971 | Submission Open

Keywords: pathophysiology; biomarker; diagnosis/prognosis/predictive/monitoring (indication/limitations); treatment advances; intensive; less intensive; refractory leukemia; cellular therapies

(This special issue belongs to the Section Hematology)

Biliary Tract Cancer Updates: Advancements and Insights

edited by Kristen R. Spencer

submission deadline 15 Mar 2026 | 9 articles | Viewed by 28262 | Submission Open

Keywords: biliary tract cancer; intrahepatic cholangiocarcinoma; extrahepatic cholangiocarcinoma; gallbladder cancer; targeted therapy; immunotherapy; molecular profiling; clinical trials

(This special issue belongs to the Section Gastrointestinal Oncology)

An In-Depth Review of Desmoid Tumours

edited by

Lloyd Mack

submission deadline 15 Mar 2026 | 4 articles | Viewed by 11624 | Submission Open

Keywords: desmoid tumour; desmoid-like fibromatosis; active surveillance; molecular pathogenesis; surgery and margins; radiation therapy; chemotherapy; novel treatment options; functional outcomes; quality of life

(This special issue belongs to the Section Bone and Soft Tissue Oncology)

Cost Effectiveness vs. Affordability in the Age of Targeted Drug Therapies

edited by Ramy Saleh

submission deadline 15 Mar 2026 | 4 articles | Viewed by 11382 | Submission Open

Keywords: cost-effectiveness; affordability; drugs; financial; cancers; treatment; targeted drug therapies

(This special issue belongs to the Section Health Economics)

Clinical Advances and Therapeutic Challenges in Small-Cell Lung Cancer and Rare Thoracic Cancers

edited by

Tommaso Martino De Pas

submission deadline 20 Mar 2026 | 3 articles | Viewed by 6542 | Submission Open

Keywords: pleural mesothelioma; thymic cancer; neuroendocrine thoracic tumors; small-cell lung cancer; rare tumors; thoracic cancer

(This special issue belongs to the Section Thoracic Oncology)

Clinical Management of Cervical Cancer

edited by Vanessa Samouëlian

submission deadline 31 Mar 2026 | 5 articles | Viewed by 8891 | Submission Open

Keywords: cervical cancer; surgical treatments; de-escalation; systemic treatments; immunotherapy; biomarkers; personalized treatment

(This special issue belongs to the Section Gynecologic Oncology)

Neurofibromatosis Type 1 (NF1) Tumor Spectrum

edited by Jay Pundavela, Kyle B. Williams and R. Taylor Sundby

submission deadline 31 Mar 2026 | 2 articles | Viewed by 3543 | Submission Open

Keywords: neurofibromatosis type 1 (NF1); malignant tumors; tumor spectrum; molecular and cellular mechanisms; malignant peripheral nerve sheath tumors (MPNSTs); targeted therapies; immunotherapies; prognostic factors; survival outcomes

(This special issue belongs to the Section Neuro-Oncology)

Surgical Management of Patients with Hepatobiliary and Pancreatic Malignancies

edited by Cameron E Gaskill and Jessica E. Maxwell

submission deadline 31 Mar 2026 | 2 articles | Viewed by 2463 | Submission Open

Keywords: surgical management; hepatobiliary malignancies; pancreatic malignancies; surgical techniques; postoperative outcomes; survival rates; regional disparities; minimally invasive surgery; long-term survival; adjuvant therapies

(This special issue belongs to the Section Surgical Oncology)

Quality of Life and Management of Pediatric Cancer

edited by

Luca Giacomelli

and

Momcilo Jankovic

submission deadline 30 Apr 2026 | 4 articles | Viewed by 9532 | Submission Open

Keywords: pediatric palliative care; oncology; quality of life; early management

(This special issue belongs to the Section Childhood, Adolescent and Young Adult Oncology)

Advances in Geriatric Oncology: Toward Optimized Cancer Care

edited by Michael J. Lind

submission deadline 30 Apr 2026 | 6 articles | Viewed by 7379 | Submission Open

Keywords: oncogeriatrics; clinical trials; prehabilitation; elderly cancer patients; cancer care

(This special issue belongs to the Section Palliative and Supportive Care)

Health Disparities and Outcomes in Cancer Survivors

edited by

Claire Jungyoun Han

submission deadline 30 Apr 2026 | 3 articles | Viewed by 5358 | Submission Open

Keywords: cancer survivorship; quality of life; social behavioral determinants of health (SBDH); health disparities; symptom management

(This special issue belongs to the Section Psychosocial Oncology)

Health Economics in Oncology: Addressing Financial Toxicity, Value-Based Care, and Equity

edited by Marcell Csanádi

submission deadline 30 Apr 2026 | 1 articles | Viewed by 1214 | Submission Open

Keywords: financial toxicity; cost-effectiveness; value-based care; cancer care; economic sustainability; health policy; treatment affordability; underserved populations; digital health; oncology economics

(This special issue belongs to the Section Health Economics)

AI-Powered Oncologic Nuclear Medicine in Clinical Translation: Advanced Assessment of Tumor Load and Microenvironment

edited by

Christian Furth

submission deadline 30 Apr 2026 | 1 articles | Viewed by 808 | Submission Open

Keywords: AI in nuclear medicine; PET- and SPECT-imaging; radiomics and deep learning; tumor microenvironment; tumor burden quantification; theranostics; precision oncology; immuno-oncology imaging; clinical translation; predictive modeling

Surgery in Locally Advanced Non-Small Cell Lung Cancer

edited by Marc Boada

submission deadline 30 Apr 2026 | 1 articles | Viewed by 672 | Submission Open

Keywords: lung cancer; pancoast tumor; locally advanced tumor; thoracic surgery; oligometastatic disease; salvage surgery

(This special issue belongs to the Section Thoracic Oncology)

Microsurgical Management of Chronic Cancer-Related Lymphedema

edited by Elisabeth A. Kappos and

Adriano Fabi

submission deadline 30 Apr 2026 | Viewed by 224 | Submission Open

Keywords: microsurgery; chronic cancer-related lymphedema; lymphatic reconstruction; surgical techniques; quality of life

(This special issue belongs to the Section Surgical Oncology)

Management of Orbital Tumors

edited by

Peerooz Saeed

submission deadline 30 Apr 2026 | Viewed by 210 | Submission Open

Keywords: orbital tumor; diagnostic; multidisciplinary approaches; personalized treatment; imaging techniques

Shaping the Future of Oncology: The Role of Generative AI in Clinical and Research Environments

edited by

Matthias May

, Emily Rinderknecht and Maximilian Haas

submission deadline 31 May 2026 | 7 articles | Viewed by 11996 | Submission Open

Keywords: generative AI in oncology; AI-driven cancer diagnostics; personalized cancer treatment; AI in clinical decision making; oncology research innovation; AI-assisted therapeutic strategies; cancer care technology; patient-centered AI tools and apps; translational oncology and AI; future of oncology; artificial intelligence

Innovative Therapeutic Strategies, Biomarkers, and Molecular Pathways in Gastrointestinal and Hepatobiliary Cancers

edited by Anwaar Saeed and

Azhar Saeed

submission deadline 31 May 2026 | 5 articles | Viewed by 10452 | Submission Open

Keywords: gastrointestinal cancers; hepatobiliary cancers; immunotherapy; targeted therapies; combination treatments; biomarkers; early diagnosis; prognosis; personalized medicine; molecular pathways; drug development targets

(This special issue belongs to the Section Gastrointestinal Oncology)

Feature Advancements in Section "Childhood, Adolescent and Young Adult Oncology"

edited by

Katrin Scheinemann

and Maria Otth

submission deadline 31 May 2026 | 2 articles | Viewed by 7598 | Submission Open

Keywords: childhood; adolescent and young adult cancer; survivorship; care models; transition; rehabilitation

(This special issue belongs to the Section Childhood, Adolescent and Young Adult Oncology)

Surgical and Medical Management of Pancreatic Tumors: Indication, Techniques, and Prognostic Factors

edited by

Michele Tedeschi

, Antonella Delvecchio and Riccardo Memeo

submission deadline 31 May 2026 | 1 articles | Viewed by 670 | Submission Open

Keywords: pancreatic tumors; pancreatic surgery; neoadjuvant therapy; adjuvant therapy; short- and long-term outcomes; pancreatic diseases; surgical complication; recurrence rate; medical management; prognostic factors

(This special issue belongs to the Section Surgical Oncology)

Innovation in Gynecologic Cancer Surgery

edited by

Sarfraz Ahmad

submission deadline 31 May 2026 | 1 articles | Viewed by 508 | Submission Open

Keywords: hysterectomy; gynecologic cancers; surgical oncology; minimally invasive surgery; fertility preservation; survivorship; cost-effectiveness

(This special issue belongs to the Section Gynecologic Oncology)

Hypofractionated Radiotherapy for Prostate Cancer: Emerging Evidence and Clinical Practice

edited by

Hiromichi Ishiyama

submission deadline 31 May 2026 | Viewed by 208 | Submission Open

Keywords: hypofractionated radiotherapy; prostate cancer; ultra-hypofractionation; image-guided radiotherapy (IGRT); toxicity and outcomes; patient selection; radiotherapy techniques; combined modality therapy

(This special issue belongs to the Section Genitourinary Oncology)

Gastrointestinal Tumors: Prevention, Screening and Predictive Analytics

edited by Mohamed I. Elsaid,

Electra D. Paskett

and Vinod Rustgi

submission deadline 1 Jun 2026 | 1 articles | Viewed by 337 | Submission Open

Keywords: gastrointestinal and hepatobiliary cancers; prevention and screening; chemoprevention; risk stratification; biomarkers and liquid biopsy (ctDNA); imaging and radiomics; predictive analytics and machine learning; causal inference; population-based studies; implementation science and health equity

(This special issue belongs to the Section Gastrointestinal Oncology)

Recent Advances in Surgical Strategies for Managing Metastatic Colorectal Cancer

edited by Fabrizio D'Acapito and Marco Vaira

submission deadline 15 Jun 2026 | 3 articles | Viewed by 5542 | Submission Open

Keywords: metastatic colorectal cancer; liver metastases; parenchymal-sparing hepatectomy; staged hepatectomy; minimally invasive liver resection; cytoreductive surgery; HIPEC; PIPAC; peritoneal surface metastases; biomarker-based stratification

(This special issue belongs to the Section Gastrointestinal Oncology)

The Impact of Tumor Microenvironment on Therapeutic Resistance

edited by

Ziqing Chen

submission deadline 15 Jun 2026 | Viewed by 587 | Submission Open

Keywords: tumor microenvironment; therapeutic resistance; stromal– immune crosstalk

Advances in Novel Biomarkers for Kidney Cancer

edited by Brittney Hanerhoff Cotta

submission deadline 15 Jun 2026 | Viewed by 171 | Submission Open

Keywords: kidney cancer; renal cell carcinoma; biomarkers; genomics; risk stratification; prognosis

(This special issue belongs to the Section Genitourinary Oncology)

Targeted Molecular Therapeutics for Urologic Cancers: Advances, Emerging Strategies, and the Road Ahead

edited by

Carolina D'elia

submission deadline 15 Jun 2026 | Viewed by 163 | Submission Open

Keywords: urologic neoplasm; circRNA; molecular targeted therapy; therapeutic resistance; precision medicine

(This special issue belongs to the Section Genitourinary Oncology)

Surgery and Beyond: The Evolving Landscape of Glioma Management

edited by

Andrea Landi

submission deadline 15 Jun 2026 | Viewed by 160 | Submission Open

Keywords: neurosurgery; CNS tumor; surgery; therapeutic innovations; diagnostic innovations

(This special issue belongs to the Section Neuro-Oncology)

BCMA-Directed CAR-T Therapy in Relapsed or Refractory Multiple Myeloma

edited by Al-Ola A. Abdallah

submission deadline 30 Jun 2026 | 1 articles | Viewed by 3069 | Submission Open

Keywords: BCMA-directed CAR-T therapy; multiple myeloma; relapsed multiple myeloma; refractory multiple myeloma; B-cell maturation antigen; immunotherapy; treatment outcomes

(This special issue belongs to the Section Hematology)

Recent Advances in Immune Checkpoint Inhibition and Antibody Drug Conjugates in Urothelial Carcinoma

edited by Qian Janie Qin

submission deadline 30 Jun 2026 | 2 articles | Viewed by 3020 | Submission Open

Keywords: immune checkpoint inhibition; antibody drug conjugates; urothelial carcinoma; therapeutic combinations; biomarkers; resistance mechanisms; treatment efficacy; cancer immunotherapy

(This special issue belongs to the Section Genitourinary Oncology)

Advances in PET/CT for Predicting Cancer Outcomes

edited by Ahmad Shariftabrizi

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1464 | Submission Open

Keywords: FDG PET/CT; PSMA PET/CT; dotatate PET/CT; tumor heterogeneity; radiomics; CAR T-cell therapy; rare tumors; radiogenomics; immunotherapy; targeted therapy; PET physics; radiotracer metabolism

Prevention, Early Detection and Management of Skin Cancer

edited by

Patricia Tai

and

Kurian Joseph

submission deadline 30 Jun 2026 | 1 articles | Viewed by 573 | Submission Open

Keywords: skin cancer; dermato-oncology; cutaneous oncology; melanoma; non-melanomatous skin cancers; basal cell carcinoma; squamous cell carcinoma; Merkel cell carcinoma; sebaceous carcinoma and other adnexal carcinomas; prevention and detection; treatment; biomarkers; immunotherapy and radiotherapy; precision medicine; UV radiation; surgery; targeted therapies

Recent Advancements in the Surgical Treatment of Brain Tumors—2nd Edition

edited by

Patrick Schuss

and Florian Gessler

submission deadline 30 Jun 2026 | 1 articles | Viewed by 450 | Submission Open

Keywords: brain tumors; intraoperative imaging; supramarginal resection; fluorescence-guided surgery; awake craniotomy; complication management; neurooncology; functional mapping; neuronavigation; intraoperative radiotherapy

(This special issue belongs to the Section Neuro-Oncology)

Therapeutic Advances in Cystectomy for Bladder Cancer

edited by Saum B. Ghodoussipour

submission deadline 30 Jun 2026 | Viewed by 408 | Submission Open

Keywords: bladder cancer; cystectomy; therapeutic advances; surgical techniques; personalized treatment

(This special issue belongs to the Section Genitourinary Oncology)

PD-1 and PD-L1 in Cancer Immunotherapy

edited by

Aleksandar Obradovic

submission deadline 30 Jun 2026 | Viewed by 351 | Submission Open

Keywords: PD-1; PD-L1; cancer immunotherapy; immune checkpoint inhibitors; resistance mechanisms; combination therapies

Advancing Precision Medicine in Hepatocellular Carcinoma: The Comprehensive Role of Liquid Biopsy

edited by

Amy K. Kim

submission deadline 30 Jun 2026 | Viewed by 318 | Submission Open

Keywords: circulating tumor cells; hepatocellular carcinoma; precision medicine; tumor heterogeneity; early diagnosis; prognosis; personalized treatment

(This special issue belongs to the Section Cell Therapy)

Pain and Symptom Management in Cancer Patients

edited by Lynn R. Gauthier

submission deadline 30 Jun 2026 | Viewed by 244 | Submission Open

Keywords: cancer patients; pain management; symptom management; supportive care

Clinical Management of Lung Cancer Brain Metastases

edited by Shrinivas Rathod

submission deadline 30 Jun 2026 | Viewed by 240 | Submission Open

Keywords: lung cancer brain metastases; clinical management; radiotherapy techniques; targeted therapy; immunotherapy; multidisciplinary management; clinical trials

Recent Advances in Artificial Intelligence-Based Approaches for Breast Cancer

edited by

Ashirbani Saha

submission deadline 30 Jun 2026 | Viewed by 233 | Submission Open

Keywords: breast cancer; artificial intelligence; multimodal data; breast cancer datasets; AI model validation; benchmarking; literature appraisal; explainable AI for breast cancer; personalized medicine; generative AI for breast cancer

(This special issue belongs to the Section Breast Cancer)

Targeting KRAS in Lung Cancer: Current Status and Future Directions

edited by Sally Lau

submission deadline 30 Jun 2026 | Viewed by 184 | Submission Open

Keywords: KRAS mutations; non-small cell lung cancer; targeted therapy; KRAS G12C inhibitors; translational research; combination therapy; clinical outcomes

(This special issue belongs to the Section Thoracic Oncology)

Transforming Pancreatic Cancer Treatment: Innovations in Molecular Diagnostics and Treatment Advances

edited by Nicola Normanno,

Michele Zanoni

and

Ilario Giovanni Rapposelli

submission deadline 30 Jun 2026 | Viewed by 175 | Submission Open

Keywords: pancreatic cancer; liquid biopsy; organoids; therapy resistance; predictive biomarkers

(This special issue belongs to the Section Oncology Biomarkers)

From Innovation to Impact: Age-Adaptive Oncology for Just and Precision-Driven Care

edited by Tanyanika Phillips

submission deadline 30 Jun 2026 | Viewed by 170 | Submission Open

Keywords: age-adaptive; oncology; older adults; aging; cancer; precision medicine; biological aging; functional aging; accelerated aging; biomarkers; therapeutics

(This special issue belongs to the Section Palliative and Supportive Care)

Advances in Targeted Therapies and Pharmacogenomics of Leukemia

edited by Nicolas N Nassar

submission deadline 30 Jun 2026 | Viewed by 136 | Submission Open

Keywords: blood cancer; targeted therapy; immunotherapy; primary and secondary resistance; pharmacogenetics; combination therapy; tumor microenvironment

The Role of Targeted Therapy in Head and Neck Cancers

edited by

Rikki A.M. Brown

submission deadline 30 Jun 2026 | Viewed by 132 | Submission Open

Keywords: cancer; head and neck squamous cell carcinoma (HNSCC); targeted therapy; molecular drug targets; cancer biomarkers; personalized medicine; resistance mechanisms; combination therapies; translation oncology

(This special issue belongs to the Section Head and Neck Oncology)

Brain Metastases: Biomarkers, Diagnosis, Treatment, Prognosis and Survival

edited by Katarzyna Jerzak

submission deadline 30 Jun 2026 | Viewed by 131 | Submission Open

Keywords: brain metastases; biomarkers; diagnosis and imaging; targeted and immunotherapy; prognosis and survival

(This special issue belongs to the Section Neuro-Oncology)

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