Bone Regeneration and Tissue Reconstruction in Dentistry

A special issue of Dentistry Journal (ISSN 2304-6767).

Deadline for manuscript submissions: 31 January 2025 | Viewed by 1227

Special Issue Editor


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Guest Editor
1. Päijät-Häme Joint Authority for Health and Wellbeing, Department of Oral and Maxillofacial Surgery, Central Hospital, 15850 Lahti, Finland
2. Clinicum, Faculty of Medicine, University of Helsinki, 00014 Helsinki, Finland
3. Cleft Palate and Craniofacial Center, Department of Plastic Surgery, HUS Helsinki University Hospital and University of Helsinki, 00029 Helsinki, Finland
Interests: maxillo-facial surgery; orthognathic surgery; virtual surgical planning; deformity surgery; CAD-CAM; patient-specific implants; medical modeling; facial trauma

Special Issue Information

Dear Colleagues,

Oral and maxillo-facial deformities, trauma, and various diseases can lead to impaired function and facial aesthetics. Long-lasting and functional reconstructions of facial structures often require a multidisciplinary approach and, sometimes, various operations with a focus on both bone and soft tissue reconstruction. Virtual surgical planning and medical modeling assistance through collaborations among all specialties in the field of dentistry represent everyday practice in most offices. Additionally, the development of bone and soft tissue substitutes and alloplastic materials, as well as surgical techniques, are rendering the reconstruction toolkit more and more versatile. However, a proper understanding of the basics of tissue reconstruction, deformity surgery, and a combination of surgical, periodontal, and prosthodontic techniques is essential and should be based on scientific background knowledge.

We welcome submissions of papers addressing the topics listed above for this Special Issue, including in vitro and animal models, clinical studies, epidemiological surveys, clinical trials, reviews, and meta-analyses. The Special Issue will focus on novel technigues such as additive manufacturing. It will also feature reports on novel materials and novel imaging and modeling techniques.

Dr. Juho Suojanen
Guest Editor

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Keywords

  • bone grafting
  • bone substitutes
  • soft tissue regeneration
  • orthognathic surgery
  • virtual surgical planning
  • deformity surgery
  • CAD-CAM structures
  • patient-specific implants
  • additive manufacturing
  • implantology

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Published Papers (1 paper)

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13 pages, 1522 KiB  
Systematic Review
Hyaluronic Acid in Bone Regeneration: Systematic Review and Meta-Analysis
by Claudia Lorenzi, Andrea Leggeri, Ilaria Cammarota, Paolo Carosi, Vincenzo Mazzetti and Claudio Arcuri
Dent. J. 2024, 12(8), 263; https://doi.org/10.3390/dj12080263 - 19 Aug 2024
Viewed by 964
Abstract
Aim: The aim of this systematic review and meta-analysis was to assess possible histomorphometric differences in new bone formation and in remaining graft particles when hyaluronic acid (HA) was added and mixed with graft materials in bone regeneration. Materials and methods: This review [...] Read more.
Aim: The aim of this systematic review and meta-analysis was to assess possible histomorphometric differences in new bone formation and in remaining graft particles when hyaluronic acid (HA) was added and mixed with graft materials in bone regeneration. Materials and methods: This review was registered at the International Prospective Register of Systematic Reviews (PROSPERO) of the National Institute of Health Research (registration number CRD42024530030). Electronic research was performed, and involved studies published up to 29 February 2024 using a specific word combination. The primary outcome was to assess possible histomorphometric differences in new bone formation and in remaining graft particles when HA was added and mixed with graft materials in bone regeneration. The search resulted in 138 potential studies. Meta-analyses were performed using the fixed and random effects model to identify significant changes in new bone formation and in the remaining graft particles. Results: After screening procedures, only three randomized controlled trials fulfilled the inclusion criteria and were selected for qualitative and quantitative analysis. The effect size of HA in the new bone formation was not statistically significant at 95% CI (Z = 1.734, p-value = 0.083, 95 % CI -,399; 6516). The effect size of HA in the remaining graft particles was not statistically significant at 95% CI (Z = −1.042, p-value = 0.297, CI -,835; 255). Conclusions: Within the limitations of the present systematic review and meta-analysis, the addition of HA to bone graft did not result in significant changes in bone regeneration procedures in terms of new bone formation and residues, even if the included studies showed encouraging and promising results. Full article
(This article belongs to the Special Issue Bone Regeneration and Tissue Reconstruction in Dentistry)
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