Oral Microbiology and Immunology: Present Research, Challenges and Development

Dear Colleagues,

The oral cavity is a complex environment with constant challenges from various antigens from the food, the air, and the oral microbiome. The mouth is the habitat of many commensal microbial species, but also of certain opportunistic pathogens. Under specific conditions, exogenous pathogens may colonize oral sites and cause disease. The immune system, especially the mucosal immune system, protects the oral cavity from pathogens and contributes to the local homeostasis. The complex interplay between the microbiome and the host defense involves several mechanisms that contribute to the system's overall function. Our modern understanding of the etiopathogenesis of the most prevalent oral diseases, caries and periodontal diseases, focuses on ecological changes as the important factors for disease development. The role of the defense system as a double-edge sword is recognized in the pathogenesis of periodontal diseases.

Undoubtfully, our knowledge in the field of oral microbiology and immunology significantly increased during the past years. However, there is more to be discovered and we need to conduct more studies to better understand the nature of oral diseases and to improve their treatment and prevention.

This Special Issue will publish new information on oral microbiology and immunology. All reviews, research articles, and clinical articles are welcome.

Prof. Dr. Sotirios Kalfas
Guest Editor

Manuscript Submission Information

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• oral microbiology
• dental plaque
• oral mucosa
• oral diseases
• immunology
• periodontitis
• dental caries
• oral infections
• biofilm