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Dentistry Journal
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Editorial Board Members’ Collection Series: Laser in Oral Surgery, Diagnosis...
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Editorial Board Members’ Collection Series: Laser in Oral Surgery, Diagnosis and Oncology

A special issue of Dentistry Journal (ISSN 2304-6767). This special issue belongs to the section "Lasers in Dentistry".

Deadline for manuscript submissions: 25 July 2025 | Viewed by 4322

Special Issue Editors

Prof. Dr. Umberto Romeo

E-Mail Website
Guest Editor
Department of Oral and Maxillofacial Sciences, Sapienza University of Rome, 00161 Rome, Italy
Interests: oral pathology; oral medicine; oral cancer; oral surgery; laser
Special Issues, Collections and Topics in MDPI journals
Prof. Dr. Paolo Vescovi

E-Mail Website
Guest Editor
Department of Medicine and Surgery, Oral Medicine and Laser Surgery Unit, University of Parma, 43100 Parma, Italy
Interests: biphosphonate inducing oral bone necrosis; oral cancer managements; oral pathology; oral laser surgery
Prof. Dr. Eiichiro Ariji

E-Mail Website
Guest Editor
Department of Oral and Maxillofacial Radiology, School of Dentistry, Aichi Gakuin University, Nagoya 464-8651, Japan
Interests: radiology; diagnostic imaging; computed tomography; ultrasound imaging; radiotherapy of oral cancer

Special Issue Information

Dear Colleagues,

We are pleased to announce this Special Issue titled “Editorial Board Members’ Collection Series: Laser in Oral Surgery, Diagnosis and Oncology”.

The aim is to provide a venue for networking and communication between Dentistry Journal and scholars in the field of laser in oral surgery, diagnosis, and oncology. All papers will be fully open access upon publication after peer review.

Feel free to contact the Managing Editor Ms. Adele Min (adele.min@mdpi.com) or our editorial office (dentistry@mdpi.com) if you have any requests.

We look forward to receiving your excellent work.

Prof. Dr. Umberto Romeo
Prof. Dr. Paolo Vescovi
Prof. Dr. Eiichiro Ariji
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Dentistry Journal is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

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Further information on MDPI's Special Issue policies can be found here.

Published Papers (2 papers)

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14 pages, 9800 KiB  
Article
Photobiomodulation in Patients Taking Denosumab: Case Report and Literature Review
by Gianluigi Caccianiga, Antonio Barbarisi, Paolo Caccianiga, Dorina Lauritano and Saverio Ceraulo
Dent. J. 2025, 13(3), 128; https://doi.org/10.3390/dj13030128 - 13 Mar 2025
Viewed by 440
Abstract
Background: Denosumab is a human monoclonal antibody playing a central role in bone resorption. The impaired bone healing observed in patients on denosumab is linked to the drug’s inhibition of osteoclast activity. Photobiomodulation (PBM) has garnered attention as a potential adjunctive therapy for [...] Read more.
Background: Denosumab is a human monoclonal antibody playing a central role in bone resorption. The impaired bone healing observed in patients on denosumab is linked to the drug’s inhibition of osteoclast activity. Photobiomodulation (PBM) has garnered attention as a potential adjunctive therapy for managing oral complications in patients on denosumab therapy. The aim of this study is to provide a review of the literature regarding the benefits of photobiomodulation therapy in patients taking denosumab while providing a case report of a patient treated with this therapy. Materials and Methods: Key terms were used to search PubMed (MEDLINE), Scopus, and Web of Science, and at last, 25 articles were compared. Following the proposed review, a case of a patient is illustrated. Results: Based on our literature findings, there are no papers regarding the benefits of photobiomodulation therapy in patients taking denosumab specifically, but there are articles regarding photobiomodulation therapy and MRONJ osteonecrosis patients, which can be caused by denosumab. Discussion: Despite all the limitations of the data in the literature, it can be deduced that there are evident benefits of photobiomodulation therapy in patients taking denosumab. The integration of laser-assisted techniques and photobiomodulation into MRONJ management protocols represents a significant evolution in treatment strategies. Conclusions: Further studies are needed to better understand a potential association between odontoclasts (which can cause external root resorption) and neoplastic disease or medication, as well as to explore the role of photobiomodulation in the therapeutic rehabilitation process. Full article
(This article belongs to the Special Issue Editorial Board Members’ Collection Series: Laser in Oral Surgery, Diagnosis and Oncology)
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Review

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24 pages, 1388 KiB  
Review
The Impact of Laser Thermal Effect on Histological Evaluation of Oral Soft Tissue Biopsy: Systematic Review
by Gianluca Tenore, Ahmed Mohsen, Alessandro Nuvoli, Gaspare Palaia, Federica Rocchetti, Cira Rosaria Tiziana Di Gioia, Andrea Cicconetti, Umberto Romeo and Alessandro Del Vecchio
Dent. J. 2023, 11(2), 28; https://doi.org/10.3390/dj11020028 - 18 Jan 2023
Cited by 14 | Viewed by 3100
Abstract
The aim of the study is to review the literature to observe studies that evaluate the extent of the thermal effect of different laser wavelengths on the histological evaluation of oral soft tissue biopsies. An electronic search for published studies was performed on [...] Read more.
The aim of the study is to review the literature to observe studies that evaluate the extent of the thermal effect of different laser wavelengths on the histological evaluation of oral soft tissue biopsies. An electronic search for published studies was performed on the PubMed and Scopus databases between July 2020 and November 2022. After the selection process, all the included studies were subjected to quality assessment and data extraction processes. A total of 28 studies met the eligibility criteria. The most studied laser was the carbon dioxide (CO2) laser, followed by the diode laser 940 nm–980 nm. Six studies were focused on each of the Erbium-doped Yttrium Aluminium Garnet (Er:YAG), Neodymium-doped Yttrium Aluminum Garnet (Nd:YAG) lasers, and diode lasers of 808 nm and 445 nm. Three studies were for the Potassium Titanyl Phosphate (KTP) laser, and four studies were for the Erbium, Chromium-doped Yttrium, Scandium, Gallium, and Garnet (Er,Cr:YSGG) laser. The quality and bias assessment revealed that almost all the animal studies were at a low risk of bias (RoB) in the considered domains of the used assessment tool except the allocation concealment domain in the selection bias and the blinding domain in the performance bias, where these domains were awarded an unclear or high score in almost all the included animal studies. For clinical studies, the range of the total RoB score in the comparative studies was 14 to 23, while in the non-comparative studies, it was 11 to 15. Almost all the studies concluded that the thermal effect of different laser wavelengths did not hinder the histological diagnosis. This literature review showed some observations. The thermal effect occurred with different wavelengths and parameters and what should be done is to minimize it by better adjusting the laser parameters. The extension of margins during the collection of laser oral biopsies and the use of laser only in non-suspicious lesions are recommended because of the difficulty of the histopathologist to assess the extension and grade of dysplasia at the surgical margins. The comparison of the thermal effect between different studies was impossible due to the presence of methodological heterogeneity. Full article
(This article belongs to the Special Issue Editorial Board Members’ Collection Series: Laser in Oral Surgery, Diagnosis and Oncology)
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