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Dentistry Journal
Special Issues
Oral and Dental Clinical Trials
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Oral and Dental Clinical Trials

A special issue of Dentistry Journal (ISSN 2304-6767).

Deadline for manuscript submissions: closed (31 October 2022) | Viewed by 8370

Special Issue Editor

Dr. Ana Andabak Rogulj

E-Mail Website
Guest Editor
Department of Oral Medicine, School of Dental Medicine University of Zagreb, 10000 Zagreb, Croatia
Interests: oral mucosal diseases; oral potentially malignant lesions; oral health care of medically compromised patients

Special Issue Information

Dear Colleagues,

Clinical studies are a very important, as well as an indispensable, part of modern medicine, disease management and health care. A type of research study that tests how well new medical approaches work on human health is urgently needed. These studies test new methods of screening, prevention, diagnosis, or treatment of a disease.

As we all know, clinical studies are much more than routine clinical work with a patient. So, in order to conduct a proper clinical study with quality, additional time, knowledge, an organized study team, space and equipment are required.

With this Special Issue, I am inviting you to present your best current clinical studies with particular attention on the prevention, diagnosis and treatment of oral mucosal diseases and conditions affecting the maxillofacial region. Furthermore, any clinical study which provides new data (prevention, diagnostics and treatment) on oral health improvement, in general, are welcomed.

Dr. Ana Andabak Rogulj
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Dentistry Journal is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • oral mucosal diseases
  • oral health
  • prevention
  • diagnostics
  • treatment
  • clinical study

Published Papers (2 papers)

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Research

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8 pages, 383 KiB  
Article
Lipid Profiles and Cardiovascular Risk in Patients with Oral Lichen Planus
by Tomislav Radic, Livia Cigic, Ana Glavina, Ana Hrboka, Ana Druzijanic, Ivona Musa Leko and Dolores Biocina-Lukenda
Dent. J. 2022, 10(4), 61; https://doi.org/10.3390/dj10040061 - 6 Apr 2022
Cited by 4 | Viewed by 2295
Abstract
Background: It has been reported that dyslipidemia prevalence and cardiovascular disease risk were increased in subjects with oral lichen planus diagnose. On the other hand, so far, there is no available data on the topic of cardiovascular risk (CVR) in subjects with oral [...] Read more.
Background: It has been reported that dyslipidemia prevalence and cardiovascular disease risk were increased in subjects with oral lichen planus diagnose. On the other hand, so far, there is no available data on the topic of cardiovascular risk (CVR) in subjects with oral lichen planus (OLP). The main aim of this study, due to lack of any other study covering this topic, was to investigate lipid profile and assess CVR in patients with OLP. Materials and Methods: To create a routine lipid profile, we collected triglyceride serum levels, total cholesterol, low-density lipoprotein cholesterol, and high-density lipoprotein cholesterol from 63 OLP patients and 63 healthy people representing control subjects. For every patient their individual cardiovascular risk was measured. Results: In comparison with the tested control subjects, patients with OLP had all parameters of the lipid profile elevated, with no differences of statistical importance. Furthermore, the experimental (OLP) and control groups shared similar mean values of the lipid profile parameters. Conclusions: The association of OLP with cardiovascular risk was not established and further studies with more subjects involved are required to validate this connection. Full article
(This article belongs to the Special Issue Oral and Dental Clinical Trials)
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Review

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17 pages, 2410 KiB  
Review
Osteonecrosis of the Jaw
by Božana Lončar Brzak, Lorena Horvat Aleksijević, Ema Vindiš, Iva Kordić, Marko Granić, Danica Vidović Juras and Ana Andabak Rogulj
Dent. J. 2023, 11(1), 23; https://doi.org/10.3390/dj11010023 - 9 Jan 2023
Cited by 7 | Viewed by 5316
Abstract
Osteonecrosis of the jaw is a condition in which bone cells die due to various causes. It is classified as drug-induced jaw osteonecrosis, osteoradionecrosis, traumatic, non-traumatic, and spontaneous osteonecrosis. Antiresorptive or antiangiogenic drugs cause drug-induced osteonecrosis. The combination of medications, microbial contamination, and [...] Read more.
Osteonecrosis of the jaw is a condition in which bone cells die due to various causes. It is classified as drug-induced jaw osteonecrosis, osteoradionecrosis, traumatic, non-traumatic, and spontaneous osteonecrosis. Antiresorptive or antiangiogenic drugs cause drug-induced osteonecrosis. The combination of medications, microbial contamination, and local trauma induces this condition. Osteoradionecrosis is a severe radiation therapy side effect that can affect people with head and neck cancer. It is described as an exposed bone area that does not heal for longer than three months after the end of radiation treatment with the absence of any indications of an original tumor, recurrence, or metastasis. Trauma (tooth extraction), tumor site, radiation dose that the patient receives, the area of the bone which is irradiated, oral hygiene, and other factors are risk factors for the development of osteonecrosis. Less frequently, osteonecrosis can also be induced by non-traumatic and traumatic causes. Non-traumatic osteonecrosis is brought on by infections, acquired and congenital disorders, as well as the impact of chemicals. Traumatic osteonecrosis is brought on by thermal, mechanical, or chemical damage. The treatment of osteonecrosis can be conservative, which aims to be beneficial for the patient’s quality of life, and surgical, which involves debridement of the necrotic bone. Full article
(This article belongs to the Special Issue Oral and Dental Clinical Trials)
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