Advanced Soft Gels with Enhanced Functionality for Biomedical and Additive Manufacturing Applications

A special issue of Gels (ISSN 2310-2861). This special issue belongs to the section "Gel Processing and Engineering".

Deadline for manuscript submissions: 30 December 2024 | Viewed by 771

Special Issue Editors

Advanced Polymer and Composite Materials Laboratory, Department of Engineering, School of Computing, Engineering and Mathematical Sciences, La Trobe University, Bendigo, VIC 3552, Australia
Interests: biomaterials and scaffolds; biodegradable materials; composite and hybrid materials; chemistry and physics of hydrogels; nanomaterials; nanotechnology; tissue engineering
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Guest Editor
Advanced Polymer and Composite Materials Laboratory, Department of Engineering, School of Computing, Engineering and Mathematical Sciences, La Trobe University, Bendigo, VIC 3552, Australia
Interests: biomaterials and scaffolds; manufacturing process and technologies; tissue engineering and regenerative medicine; hydrogels; biodegradable materials

Special Issue Information

Dear Colleagues,

Soft gels, also known as hydrogels, microgels, and nanogels, are on the rise in the biomedical field. Their ability to be prepared under bio-friendly conditions and their promising properties are sparking enthusiasm. Soft gels, with their three-dimensional network and high water content, are not prone to disintegration or dissolution in excess water. They can be combined with cells to create two or three-dimensional scaffolds, eliminating the need for complicated fabrication processes or surgical procedures. Moreover, soft gels offer tunable mechanical properties, biodegradability, and biocompatibility, making them a beacon of hope for biomedical applications such as drug delivery, biosensors, 3D cell culture, tissue engineering, 3D bioprinting, and wound healing.

Despite the numerous advantages of soft gels, they still face significant challenges, particularly in terms of poor stability and mechanical properties. This underscores the urgent need for further research and development of new and advanced soft gels with significantly improved functionality and practical application, a need that is crucial for the medical field.

This Special Issue, a platform to showcase the latest advancements in soft gel technology, holds the potential to influence the field significantly. It encompasses natural, synthetic, and derivative gels applicable to advanced manufacturing techniques, drug delivery, and tissue engineering. We eagerly await submissions that delve into essential aspects of hydrogels, such as gel synthesis and development, physiochemical characterisation, biocompatibility, and practical application research.

Dr. Ing Kong
Dr. Akesh Babu Kakarla
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Gels is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2100 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • synthesis
  • characterisation
  • physiochemical properties
  • biodegradation
  • synthetic and natural polymers
  • biopolymers
  • physical and chemical crosslinking
  • composite gels
  • self-healing gels
  • cell culture
  • drug delivery
  • 3D printing and bioprinting
  • tissue engineering
  • hydrogels
  • microgels
  • nanogels

Published Papers (1 paper)

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Research

11 pages, 2081 KiB  
Article
Adsorption Capacity of Activated Carbon-Encapsulated Hollow-Type Spherical Bacterial Cellulose Gels for Uremic Toxins in a Simulated Human Gastrointestinal Environment
by Aya Hirai, Masashige Suzuki, Kaito Sato, Toru Hoshi and Takao Aoyagi
Gels 2024, 10(7), 417; https://doi.org/10.3390/gels10070417 - 25 Jun 2024
Viewed by 579
Abstract
To reduce the risk of the adsorption of granular activated carbon in the gastrointestinal tract, we successfully produced a hollow-type spherical bacterial cellulose (HSBC) gel containing activated carbon with a particle size of 6 μm. In this study, the aim of which was [...] Read more.
To reduce the risk of the adsorption of granular activated carbon in the gastrointestinal tract, we successfully produced a hollow-type spherical bacterial cellulose (HSBC) gel containing activated carbon with a particle size of 6 μm. In this study, the aim of which was to develop an effective formulation, we evaluated the stability of activated-carbon-encapsulating HSBC gels under various pH conditions. Activated-carbon-encapsulating HSBC gels (ACEGs) retained the activated carbon without leaking when subjected to agitation in acidic or basic environments. The saturated adsorption amount, calculated using the Langmuir adsorption isotherm, was affected by the target adsorbate and pH conditions. These results indicate that ACEGs can adsorb uremic toxins and their precursors similarly to conventional uremic toxin adsorbents while preventing direct contact between the encapsulated activated carbon and the gastrointestinal tract. Compared to powdered activated carbon, the ACEG is less likely to be adsorbed in the gastrointestinal tract. Therefore, the proposed ACEG is a promising new formulation that will contribute to the treatment of renal failure and improve patients’ compliance with medication. Full article
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