Hydrogel-Based Scaffolds with a Focus on Medical Use (2nd Edition)

Dear Colleagues,

The development of scaffolds with optimal characteristics is more readily achievable in polymeric scaffolds. There is currently great research interest in hydrogel-based scaffolds. 

Hydrogel-based scaffolds have recently emerged as the most promising substrates for cell cultures to generate well-defined 3D biofabricated tissue, attracting significant research attention for their potential in medical applications.

These scaffolds act as bioactive substrates and structural supports, providing topographical and chemical stimuli for cell spreading, proliferation and differentiation in vivo. Among the specific scaffold characteristics, high porosity and interconnectivity to facilitate scaffold/cell interactions, nutrient and oxygen infiltration and vascularization aim to obtain specific cellular responses. Scaffolds have sufficient mechanical properties to temporarily substitute the missing tissue and permit essential physiological functions.

This Special Issue is dedicated to the design and development of advanced polymeric scaffolds and their applications for bone/cartilage/skin regeneration in vitro and in vivo.

Dr. Federica Re
Dr. Elisa Borsani
Guest Editors

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• hydrogel-based scaffolds
• resorbable scaffolds
• synthesis of biomaterials
• mesenchymal stromal cells
• bioengineered models
• bone regeneration
• cartilage regeneration
• skin regeneration

• Hydrogel-Based Scaffolds with a Focus on Medical Use in Gels (9 articles)

1.
Type of Paper: Article

Tentative Title: Antimicrobial Polyvinyl Alcohol-Nanolignin Composite Hydrogel Scaffold for Potential Surgical Sponge Applications

Authors: Resmi Anand, Delphine Collard Jean-Sébastien Thomann and David Duday

Affiliations: Department of Materials Research and Technology, Luxembourg Institute of Science and Technology, L-4362 Esch-Sur-Alzette, Luxembourg

2.

Type of Paper: Review
Tentative Title: Bioprinting by Design for in-situ Skin Tissue Engineering 
Authors: Alisa Douglas(1,2), Yufei Chen(2), Margarita Elloso(2), Adam Levschuk(2,3), Marc. G Jeschke(2,4)
Affiliations: (1) School of Biomedical Engineering, McMaster University
(2) Hamilton Health Sciences
(3) Schulich School of Medicine and Dentistry, Western University
(4) Department of Surgery, McMaster University

3.

Type of Paper:Article
Tentative Title: Cellulose structuring effect on engineered chitosan scaffolds for bone regeneration
Authors: Laura Furlan1, Annj Zamuner1,2, Antonio Gloria3,4, Teresa Russo3, Gabriella D’Auria5, Lucia Falcigno5, Lucia Manni6, Loriano Ballarin6, Elisabetta Schievano7, Paola Brun8, Monica Dettin1,*

Affiliations:

1: Department of Industrial Engineering, University of Padova, 35131 Padova, Italy
2: Department of Civil, Architectural and Environmental Engineering, University of Padova, 35131 Padova, Italy
3: Department of Industrial Engineering, University of Naples Federico II, 80125 Naples, Italy
4: Institute of Polymers, Composites and Biomaterials, National Research Council of Italy, 80125 Naples, Italy
5: Department of Pharmacy, University Federico II of Naples, 80131 Naples, Italy
6: Department of Biology, University of Padova, 35131 Padova, Italy
7: Department of Chemical Sciences, University of Padova, 35131 Padova, Italy
8: Department of Molecular Medicine, University of Padova, 35121 Padua, Italy