Smart Hydrogel System
A special issue of Gels (ISSN 2310-2861).
Deadline for manuscript submissions: closed (28 January 2022) | Viewed by 2234
Special Issue Editor
Special Issue Information
Dear Colleagues,
Over the last decade, smart hydrogels have been extensively investigated for tissue engineering and regenerative medicine applications. With smart characteristics such as in situ crosslinking, multi-responsiveness, tunable stiffness, and a controllable degradation rate, this type of biomaterial can overcome the functional limitations of conventional hydrogel systems. An ideal smart hydrogel system can crosslink in situ after injection into the human body or can be delivered directly to the application site through a sol-to-gel transition. A biologically benign process is required to fabricate smart hydrogels for biomedical applications. Thus, reactions that can proceed under physiological conditions with high biocompatibility, such as Michael addition, click chemistry, Schiff base reaction, photo-crosslink reaction, and host–guest interaction are ideal for smart hydrogel fabrication. Moreover, multi-responsive properties under external stimuli including pH, thermo, light, shear force, and ionic strength are desired to be incorporated in the smart hydrogel system to meet a variety of application requirements. Development in this subject necessitates a continuous effort to achieve a more detailed understanding of complex smart hydrogel systems for real applications.
Dr. Sigen Asigen
Guest Editor
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Keywords
- responsive hydrogels
- methodology of smart hydrogel fabrication
- evaluation of novel smart hydrogels
- translational applications of smart hydrogels
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