Diagnosis and Treatment of Inherited Breast Cancer

Dear Colleagues,

This Special Issue, "Diagnosis and Treatment of Inherited Breast Cancer", aims to provide a comprehensive overview of the latest advancements in understanding, diagnosing, and managing breast cancer predisposition due to germline mutations. It will delve into the genetic landscape of inherited breast cancer, exploring the roles of well-established high-penetrance genes (e.g., BRCA1/2, TP53, and PTEN) and emerging moderate-penetrance genes, and will cover cutting-edge diagnostic approaches, including multigene panel testing, risk stratification models, and the implications of genetic findings for screening and prevention strategies. Furthermore, it will address the evolving landscape of treatment options for individuals with inherited breast cancer, encompassing targeted therapies (e.g., PARP inhibitors), surgical considerations, and radiation approaches, while also highlighting the importance of personalized medicine and genetic counseling in this context.

Dr. Maja Prutki
Dr. Ivo Dumić-Čule
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Genes is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.