Multi-Omics and Precision Medicine in Chronic Complex Diseases
A special issue of Genes (ISSN 2073-4425). This special issue belongs to the section "Human Genomics and Genetic Diseases".
Deadline for manuscript submissions: closed (5 November 2024) | Viewed by 343
Special Issue Editor
Special Issue Information
Dear Colleagues,
This Special Issue on "Multi-omics and Precision Medicine in Chronic Complex Multi-System Diseases" addresses the urgent need to understand and combat the rising prevalence of complex, chronic multi-system conditions worldwide. With diseases like neurological and metabolic diseases, and infection-induced sequelae such as ME/CFS, post-treatment Lyme disease, and long COVID on the rise, it is crucial to enhance medical practice and healthcare by providing biomarkers for early diagnosis and effective treatment. This approach aims not only to enhance the quality of life for patients but also to identify risk factors for preventive measures.
Advancements in biological and computer sciences now enable real-time precision medicine. Through integrative multi-omics approaches including genomics, transcriptomics, proteomics, metabolomics, microbiome analysis, antibody profiling, and epigenomics, alongside clinical and health data, we can understand the molecular mechanisms underlying these diseases, including their etiology, progression, and heterogeneity.
In this Special Issue, we aim to showcase cutting-edge research and innovative methodologies that shed light on the complex interplay between genetic, environmental, and physiological factors in chronic complex multi-system diseases. Our goal is to foster the development of personalized treatment strategies and targeted therapies tailored to individual patients based on multi-omics profiling. By identifying biomarkers for early diagnosis and effective therapeutics, we aim to deliver a healthier lifespan to patient populations worldwide.
We invite original research articles, reviews, and perspectives addressing various key themes, including biomarker identification, integration of multi-omics data, precision medicine approaches, novel technologies for data analysis, understanding disease pathophysiology, and exploring comorbidities in chronic complex multi-system diseases, alongside those resulting from post-infection or environmental trauma.
By bringing together contributions from researchers and clinicians across diverse disciplines, this Special Issue aims to advance our understanding of chronic complex multi-system diseases and accelerate the translation of multi-omics discoveries into clinical practice. Together, we can pave the way for personalized interventions and improved outcomes for patients affected by these challenging conditions.
We look forward to your valuable contributions to this Special Issue.
Dr. Fereshteh Jahanbani
Guest Editor
Manuscript Submission Information
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Keywords
- multi-omics
- precision medicine
- chronic complex multi-system diseases
- biomarkers
- health outcomes
- targeted therapies
- disease mechanisms
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