Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
5.2
2.8
Journals
Genes
Special Issues
Role of Gametes’ Genetics and Epigenetics in Reproduction
share announcement

Role of Gametes’ Genetics and Epigenetics in Reproduction

A special issue of Genes (ISSN 2073-4425). This special issue belongs to the section "Animal Genetics and Genomics".

Deadline for manuscript submissions: closed (20 March 2022) | Viewed by 2835

Special Issue Editors

Dr. Jordi Ribas-Maynou

E-Mail Website
Guest Editor
Biotechnology of Animal and Human Reproduction (TechnoSperm), Institute of Food and Agricultural Technology, University of Girona, Girona, Spain
Interests: sperm; chromatin; gamete; reproduction; genetics
Special Issues, Collections and Topics in MDPI journals
Dr. Isabel Barranco

E-Mail Website
Guest Editor
Department of Veterinary Medical Sciences, University of Bologna, Bologna, Italy
Interests: reproduction; pig; fertilization; extracellular vesicles
Special Issues, Collections and Topics in MDPI journals
Dr. Albert Salas-Huetos

E-Mail Website
Guest Editor
1. Biotechnology of Animal and Human Reproduction (TechnoSperm), Institute of Food and Agricultural Technology, University of Girona, Girona, Spain
2. Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, USA
Interests: sperm; human; miRNAs; genetics; epigenetics
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

We would like to invite you to participate in this Special Issue, “Role of Gametes’ Genetics and Epigenetics in Reproduction”.

The great advances in assisted reproduction techniques (ART) have improved both reproduction in farm animals such as pigs and cattle and also helped infertile human couples to conceive newborns. According to the latest European Society of Human Reproduction and Embryology (ESHRE) data, human ART are still far from being absolutely effective, showing an effectiveness of around 25–30% of initiated cycles. In animals, subfertile individuals still impair production, causing economic losses. Thus, there is a need to understand the causes of these impairments, in order to deliver more effective treatments.

As both gametes are responsible for providing not only genetic but also epigenetic markers to the embryo, their contribution is broader than initially thought. Therefore, new research in genetic and epigenetic biomarkers for individuals with higher fertility rates will be essential for leading the way to new personalized treatments. 

We invite you to participate in this Special Issue.

Dr. Jordi Ribas-Maynou
Dr. Isabel Barranco
Dr. Albert Salas-Huetos
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Genes is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • sperm
  • oocyte
  • reproduction
  • genetics
  • epigenetics

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.

Further information on MDPI's Special Issue polices can be found here.

Published Papers (1 paper)

Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Research

18 pages, 12866 KiB  
Article
Pou5f1 and Nanog Are Reliable Germ Cell-Specific Genes in Gonad of a Protogynous Hermaphroditic Fish, Orange-Spotted Grouper (Epinephelus coioides)
by Chaoyue Zhong, Meifeng Liu, Yuhao Tao, Xi Wu, Yang Yang, Tong Wang, Zining Meng, Hongyan Xu and Xiaochun Liu
Genes 2022, 13(1), 79; https://doi.org/10.3390/genes13010079 - 29 Dec 2021
Cited by 7 | Viewed by 2215
Abstract
Pluripotency markers Pou5f1 and Nanog are core transcription factors regulating early embryonic development and maintaining the pluripotency and self-renewal of stem cells. Pou5f1 and Nanog also play important roles in germ cell development and gametogenesis. In this study, Pou5f1 (EcPou5f1) and [...] Read more.
Pluripotency markers Pou5f1 and Nanog are core transcription factors regulating early embryonic development and maintaining the pluripotency and self-renewal of stem cells. Pou5f1 and Nanog also play important roles in germ cell development and gametogenesis. In this study, Pou5f1 (EcPou5f1) and Nanog (EcNanog) were cloned from orange-spotted grouper, Epinephelus coioides. The full-length cDNAs of EcPou5f1 and EcNanog were 2790 and 1820 bp, and encoded 475 and 432 amino acids, respectively. EcPou5f1 exhibited a specific expression in gonads, whereas EcNanog was expressed highly in gonads and weakly in some somatic tissues. In situ hybridization analyses showed that the mRNA signals of EcNanog and EcPou5f1 were exclusively restricted to germ cells in gonads. Likewise, immunohistofluorescence staining revealed that EcNanog protein was limited to germ cells. Moreover, both EcPou5f1 and EcNanog mRNAs were discovered to be co-localized with Vasa mRNA, a well-known germ cell maker, in male and female germ cells. These results implied that EcPou5f1 and EcNanog could be also regarded as reliable germ cell marker genes. Therefore, the findings of this study would pave the way for elucidating the mechanism whereby EcPou5f1 and EcNanog regulate germ cell development and gametogenesis in grouper fish, and even in other protogynous hermaphroditic species. Full article
(This article belongs to the Special Issue Role of Gametes’ Genetics and Epigenetics in Reproduction)
►▼ Show Figures

Figure 1

Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-1
Back to TopTop