Molecular Studies of Control of Platelet Gene Expression
A special issue of Genes (ISSN 2073-4425). This special issue belongs to the section "Molecular Genetics and Genomics".
Deadline for manuscript submissions: closed (25 November 2021) | Viewed by 1972
Special Issue Editor
Interests: molecular cell biology; platelet; microRNAs; hemostasis and thrombosis; thromboinflammation
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Background: Platelets are the principal cellular agents of hemostasis by inducing clot formation, which in pathological states causes thrombosis, accounting for significant morbidity and mortality worldwide. Although platelets, derived from megakaryocyte precursors, are anucleate, control of platelet gene expression at the molecular level in both platelets and megakaryocytes has emerged as a major regulatory mode for platelet physiological functions.
Aims and scope: This article series will focus on molecular control of platelet and megakaryocyte gene expression at the mRNA and protein levels, as well as non-coding RNA expression and regulation, and developmental, cellular, physiological, and pathophysiological outcomes.
History: Though broadly overlooked for many years, recent literature has unearthed a wealth of new data and ideas indicating substantial roles for molecular control of platelet gene expression in their cellular and physiologic responses. The ability of platelets to translate new protein from existing mRNAs and to modulate translation such as through RNAi mediated by non-coding RNAs and the presence of transcription factors all point to the importance of these processes in platelet response.
Cutting-edge research: Studies in human platelets and animal models, including -omics studies, as well as molecular regulation in megakaryocytes, are at the forefront of this burgeoning field.
Manuscripts sought: Primary research articles, review articles, clinical studies, or clinical data reviews if they directly reflect the overall aims and scope of the article series.
Dr. Lawrence E. Goldfinger
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Genes is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- Platelets
- mRNA
- Megakaryocytes
- Transcription
- Translation
- Hemostasis
- Thrombosis
