Skeletal Muscle Modifications and Rehabilitation
A special issue of International Journal of Environmental Research and Public Health (ISSN 1660-4601). This special issue belongs to the section "Exercise and Health".
Deadline for manuscript submissions: closed (3 July 2023) | Viewed by 7440
Special Issue Editors
Interests: cancer rehabilitation; osteoporosis; sarcopenia; aging; physical exercise; pain management; sports medicine
Interests: rehabilitation; physical exercise; osteoporosis; sarcopenia; osteoarthritis; sports medicine; pain management; fractures; musculoskeletal disorders
Special Issues, Collections and Topics in MDPI journals
Interests: rehabilitation; osteoporosis; sarcopenia; osteoarthritis; pain management; breast cancer related lymphedema; stroke; physical exercise
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
In recent years, growing attention is rising on skeletal muscle modifications induced by inflammatory and biochemical phenomena characterizing several pathological conditions, and the consequences in terms of muscle catabolism and skeletal muscle system impairment affecting functional independence and quality of life in these patients. These issues have crucial consequences in terms of disabling sequelae, functional impairment and direct/indirect sanitary costs and the set up of effective therapeutic rehabilitative interventions is a crucial clinical priority.
Skeletal muscle modifications are a pathological feature shared by several conditions, including the aging process. Several mechanisms promoting these modifications have been proposed in the current literature, including mechanical factors, oxidative stress, nutritional status, bioenergetic metabolism, cytokines pathways and organelle turnover. However, new insights about this complex framework are continuously emerging with a specific focus on rehabilitation interventions.
On the other hand, a deeper understanding of the mechanisms underpinning skeletal muscle pathological modifications plays a key role in the complex management of rehabilitation interventions. In this context, novel paradigms like the translational approach and rapid technological advances combined with the concomitant increase in life expectancy put in light the need for new tailored and effective strategies to counter this detrimental issue.
Nevertheless, different limitations were reported in the current literature with a large gap of knowledge in specific treatment monitoring in order to optimize functional improvement. Moreover, specific rehabilitation-induced skeletal muscle modifications are far from being fully characterized.
Therefore, this Special Issue aims to provide a broad overview of the evidence supporting rehabilitation in improving skeletal muscle alterations, in order to pave the way to the future concept of precise and tailored rehabilitation programs based on specific biological features characterizing patients' pathological conditions.
Dr. Lorenzo Lippi
Prof. Dr. Alessandro de Sire
Prof. Dr. Marco Invernizzi
Guest Editors
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Keywords
- muscle
- sarcopenia
- osteoporosis
- elderly
- physical exercise
- precision medicine
- rehabilitation
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